Results 51 to 60 of about 25,700 (224)

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source

Targets of influenza human T-cell response are mostly conserved in H5N1

mBio
Frequent recent spillovers of subtype H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI) virus into poultry and mammals, especially dairy cattle, including several human cases, increased concerns over a possible future pandemic.
John Sidney, A-Reum Kim, Rory D. de Vries, Bjoern Peters, Philip S. Meade, Florian Krammer, Alba Grifoni, Alessandro Sette   +7 more
doaj   +1 more source

Predicting Hotspots for Influenza Virus Reassortment

Emerging Infectious Diseases, 2013
The 1957 and 1968 influenza pandemics, each of which killed ≈1 million persons, arose through reassortment events. Influenza virus in humans and domestic animals could reassort and cause another pandemic.
Trevon L. Fuller, Marius Gilbert, Vincent Martin, Julien Cappelle, Parviez Hosseini, Kevin Y. Njabo, Soad Abdel Aziz, Xiangming Xiao, Peter Daszak, Thomas B. Smith   +9 more
doaj   +1 more source

Investigating poultry trade patterns to guide avian influenza surveillance and control: a case study in Vietnam [PDF]

, 2016
Live bird markets are often the focus of surveillance activities monitoring avian influenza viruses (AIV) circulating in poultry. However, in order to ensure a high sensitivity of virus detection and effectiveness of management actions, poultry ...
A Bouma, A Delabouglise, AS Dean, DU Pfeiffer, E de Vries, G Fournié, G Fournié, G Fournié, HR Kim, J Chen, J Truscott, KF Shortridge, KM Pepin, LL Bulaga, M Gilbert, M Kang, NJ Savill St., NY Kung, ON Poetri, PC Pinto, R Indriani, RJ Soares Magalhaes, S Burgos, T Opsahl, YK Choi   +24 more
core   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Advances in Avian Diagnostic Pathology: Current Trends, Challenges and Future Directions: A Review

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Advances in avian diagnostic pathology integrate histopathology, immunohistochemistry, molecular diagnostics and digital pathology to enhance the detection and management of poultry diseases. Emerging tools, including machine learning and artificial intelligence, further improve diagnostic accuracy, disease surveillance and outbreak prediction.
Gebyaw Menge Getnet, Mengesha Ayehu Getnet, Ayenalem Shibabaw Atenaf   +2 more
wiley   +1 more source

Pandemic Influenza: Warning, Children At-Risk [PDF]

, 2007
Identifies gaps in U.S. preparedness for treating and caring for children during a potential pandemic flu outbreak. Makes recommendations for appropriate doses of vaccine and medications and the management and treatment of children who become ...

core  

A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale [PDF]

, 2017
Almost all human infections by avian influenza viruses (AIVs) are transmitted from poultry. A systematic review was conducted to identify practices associated with human infections, their prevalence, and rationale.
Ahad, Ai, Allen, Areechokchai, Aunger, Barennes, Barennes, Barnett, Barnett, Biran, Bridges, Cavailler, Claas, Costard, DerSimonian, Dinh, Dirk U. Pfeiffer, Edirne, Erling Høg, Fang, Fournié, Freidl, Fuller, Gomaa, Guillaume Fournié, He, Higgins, Hill, Huo, Kawaoka, Khan, Lai, Li, Li, Li, Liao, Liu, Lucas, Ma, Moher, Mounts, Negro-Calduch, Offeddu, Punam Mangtani, Rabinowitz, Rimi, Russell, Shortridge, Smith, Sterne, Sultana, Sultana, Sutanto, Tellier, Tony Barnett, Van Kerkhove, Viechtbauer, Vong, Wang, Webster, Webster, Wu, Yang, Yu, Yu, Yupiana, Zhou   +66 more
core   +2 more sources

Aggregation of Single Nucleotide Polymorphisms in a Human H5N1 Clade 2.2 Hemagglutinin [PDF]

, 2007
The evolution of H5N1 has attracted significant interest 1-4 due to linkages with avian 5,6 and human infections 7,8. The basic tenets of influenza genetics 9 attribute genetic drift to replication errors caused by a polymerase complex that lacks a ...
Abdelattar Arafa, Ahmed E. Nayel, Ahmed S. Abdelghani, Bruce R. Boynton, Ehab A. Ayoub, Emad M. Labib, Gregory A. Raczniak, Hala M. Esmat, Henry L. Niman, Jeffery Tjaden, Kenneth C. Earhart, Magdi D. Saad, Marshall R. Monteville, Mensah Agyen-Frempong, Mona M. Aly, Moustafa M. Mansour, Nasr El-Sayed, William K. Ampofo   +17 more
core   +6 more sources

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules.

PLoS ONE, 2011
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (
Anna Hultberg, Nigel J Temperton, Valérie Rosseels, Mireille Koenders, Maria Gonzalez-Pajuelo, Bert Schepens, Lorena Itatí Ibañez, Peter Vanlandschoot, Joris Schillemans, Michael Saunders, Robin A Weiss, Xavier Saelens, José A Melero, C Theo Verrips, Steven Van Gucht, Hans J de Haard   +15 more
doaj   +1 more source