Results 71 to 80 of about 114,208,328 (217)

A replication-deficient H9N2 influenza virus carrying H5 hemagglutinin conferred protection against H9N2 and H5N1 influenza viruses in mice

Frontiers in Microbiology, 2022
H5N1 and H9N2 influenza viruses have been reported to cause human infections and are believed to have pandemic potential. The vaccine is an effective tool to prevent influenza virus infection.
Weigang Ren, Shuli Pei, Wenming Jiang, Meixia Zhao, Le Jiang, Honggang Liu, Yongxiang Yi, Yongxiang Yi, Mizhou Hui, Junwei Li, Junwei Li   +10 more
doaj   +1 more source

The Involvement of the Cryptococcal Yeast Kexin Protease in the Proteolytic Activation of the Uncleaved Influenza Virus Hemagglutinin Glycoprotein

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
A haemagglutinin mimetic fluorogenic peptide assay revealed that recombinant Cryptococcus neoformans Kex2p exhibits strong haemagglutinin‐cleaving activity, suggesting a possible role for cryptococcal proteases in influenza virus activation. ABSTRACT Infectious diseases typically involve a single pathogen harming its host. However, in clinical settings,
Nolwazi F. Ntshangase, Khwezi Mdana, Nozethu Mjokane, Winschau F. van Zyl, Jacobus Albertyn, Olihile M. Sebolai   +5 more
wiley   +1 more source

Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]

, 2012
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda, Dimmock Nigel J., Dove, Brian K., Scott, P. D. (Paul D.), Carroll, Miles W., Linda Cheung, Miles W Carroll, Brian K Dove, Dove Brian K., Taylor Irene, Bassam Hallis, Meng, Bo, Easton, A. J. (Andrew J.), Marriott, Anthony C., Hallis, Bassam, Miles W. Carroll (111071), Dimmock, N. J., Linda Cheung (71020), Andrew J. Easton (111072), Irene Taylor (111066), Scott Paul D., Bo Meng (111065), Hallis Bassam, Taylor, Irene, Andrew J Easton, Paul D Scott, Bo Meng, Brian K. Dove (111063), Meng Bo, Paul D. Scott (111064), Nigel J Dimmock, Marriott Anthony C., Irene Taylor, Anthony C Marriott, Nigel J. Dimmock (111061), Carroll Miles W., Cheung Linda, Bassam Hallis (111069), Easton Andrew J., Anthony C. Marriott (111070)   +39 more
core   +2 more sources

Between‐species contagion drives HPAI transmission and mass mortality in seabirds

Journal of Animal Ecology, Volume 95, Issue 8, Page 1488-1503, August 2026.
Modelling the unprecedented avian panzootic caused by High‐Pathogenicity Avian Influenza (HPAI) across the Northeast Atlantic gannet breeding metapopulation, we estimated 28% (95% CI: 21%–34%) HPAI‐related mortality. Large‐scale outbreak initiation was best explained by external infection sources, most likely, other seabird species.
Jason Matthiopoulos, Stephen Votier, Sarah Wanless, Emma Cunningham, Jude V. Lane, Jana W. E. Jeglinski   +5 more
wiley   +1 more source

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]

, 2012
© 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Shui-Ling Chu, Béatrice Nal, Tang, D, Chi-Hong Lam, Yuen-Man Lam, Tang Dong-Jiang, Lam Chi-Hong, Lam Yuen-Man, Bruzzone Roberto, Peiris, JS, Buchy Philippe, Siu, YL, Dong-Jiang Tang, Chu Shui-Ling, Tang, DJ, Yu-Lam Siu, Nal, B, Peiris J. S. Malik, J S Malik Peiris, Peiris, J S Malik, Siu Yu-Lam, Bruzzone, R, Chu, SL, Lam, CH, Philippe Buchy, Buchy, Philippe, Tang, Dong-Jiang, Bruzzone, Roberto, Nal Béatrice, Lam, YM, Chu, Shui-Ling, Siu, Yu-Lam, Lam, Chi-Hong, Roberto Bruzzone, Peiris, JSM, Nai, B, Buchy, P, Nal, Béatrice, Lam, Yuen-Man   +38 more
core   +2 more sources

Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Despite the presence of licensed vaccines and therapeutics, influenza viruses remain a major public health concern, as they cause seasonal respiratory infections and pose a pandemic threat through the emergence of zoonotic strains. Although neutralizing antibodies elicited by seasonal vaccination constitute a primary defense against infection,
Yu Adachi, Yoshimasa Takahashi
wiley   +1 more source

Concurrent Acquisition of a Single Nucleotide Polymorphism in Diverse Influenza H5N1 Clade 2.2 Sub-clades [PDF]

, 2008
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1,2. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 3.
Hala M. Esmat, Henry Niman, Mona M. Aly, William K. Ampofo, Nasr El-Sayed, Bruce R. Boynton, Abdel-Satar Arafa, Gregory A. Raczniak, Ahmed S. Abdelghani, Ahmed E. Nayel, Mensah Agyen-Frempong   +10 more
core  

Protection and Virus Shedding of Falcons Vaccinated against Highly Pathogenic Avian Influenza A Virus (H5N1)

Emerging Infectious Diseases, 2007
Because fatal infections with highly pathogenic avian influenza A (HPAI) virus subtype H5N1 have been reported in birds of prey, we sought to determine detailed information about the birds’ susceptibility and protection after vaccination.
Michael Lierz, Hafez M. Hafez, Robert Klopfleisch, Dörte Lüschow, Christine Prusas, Jens P. Teifke, Miriam Rudolf, Christian Grund, Donata Kalthoff, Thomas C. Mettenleiter, Martin Beer, Timm Harder   +11 more
doaj   +1 more source

Prevalence of Avian Influenza Virus Subtype H5n1 in Waterfowl in West Java Province of Indonesia [PDF]

International Journal of Infectious Diseases, 2008
are commonly associated with neonatal diarrhea and dysentery in calves. It is important to determine minimal inhibitory concentrations(MICs) for the treatment of animals including human with E. coli infections. A total of 160 strains from 158 diarrheic cattle(1 day to 11 years old) were examined between April 1999 and December 2001 in Japan.
Susanti, R., Soejoedono, R.D., Mahardika, I.G.N., Wibawan, I.W.T.   +3 more
openaire   +1 more source

Determining the Environmental and Ecological Factors Associated With Poultry Farm Spillover of Highly Pathogenic Avian Influenza (H5N1) in British Columbia, Canada

Zoonoses and Public Health, Volume 73, Issue 5, Page 439-450, August 2026.
ABSTRACT Introduction Highly pathogenic avian influenza (HPAI) H5N1, clade 2.3.4.4b is a global threat causing widespread outbreaks on poultry farms and high mortality among wild bird populations in Canada. Wild aquatic birds are generally recognised as key reservoir hosts for avian influenza viruses (AIV's).
Riley Oremush, Pascale Aubry, E. Jane Parmley, Zvonimir Poljak, Amy Greer   +4 more
wiley   +1 more source