Results 21 to 30 of about 114,208,328 (217)

Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells

Respiratory Research, 2005
Background Fatal human respiratory disease associated with influenza A subtype H5N1 has been documented in Hong Kong, and more recently in Vietnam, Thailand and Cambodia. We previously demonstrated that patients with H5N1 disease had unusually high serum
Poon LLM, Long HT, Chan RWY, Chan YO, Nicholls JM, Tsao SW, Chui WH, Cheung CY, Chan MCW, Guan Y, Peiris JSM   +10 more
doaj   +1 more source

Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. [PDF]

, 2011
Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1 ...
Michaelis, Martin, Sithisarn, Patchima, Leutz, Anke, Cinatl, Jindrich, Martin Michaelis, Geiler Janina, Patrizia Naczk, Geiler, Janina, Doerr, Hans Wilhelm, Naczk, Patrizia, Sithisarn Patchima, Anke Leutz, Janina Geiler, Patchima Sithisarn, Hans Wilhelm Doerr, Jindrich Cinatl, Doerr Hans Wilhelm, Naczk Patrizia, Cinatl Jindrich, Leutz Anke, Michaelis Martin   +20 more
core   +2 more sources

Active Surveillance for Avian Influenza Virus, Egypt, 2010–2012

Emerging Infectious Diseases, 2014
Continuous circulation of influenza A(H5N1) virus among poultry in Egypt has created an epicenter in which the viruses evolve into newer subclades and continue to cause disease in humans.
Ghazi Kayali, Ahmed Kandeil, Rabeh El-Shesheny, Ahmed S. Kayed, Mokhtar M. Gomaa, Asmaa M. Maatouq, Mahmoud M. Shehata, Yassmin Moatasim, Ola Bagato, Zhipeng Cai, Adam Rubrum, Mohamed A. Kutkat, Pamela P. McKenzie, Robert G. Webster, Richard J. Webby, Mohamed A. Ali   +15 more
doaj   +1 more source

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo, García-Sastre, A., Rong Hai, Hale Benjamin G., Pena, Lindomar, Hai, Rong, John Steel, Manicassamy Balaji, Daniel R. Pérez, Pérez Daniel R., Manicassamy, Balaji, Pena, L., Benjamin G. Hale, Sutton, T., Zsuzsanna T Varga, Troy Sutton, Sutton Troy, Varga Zsuzsanna T., Hale, B.G., Varga, Zsuzsanna T, Pena Lindomar, Zsuzsanna T. Varga, Hale, Benjamin G, Balaji Manicassamy, Adolfo García-Sastre, Schmolke, M., Hai Rong, Hai, R., Daniel R Pérez, Pérez, D.R., Sutton, Troy, Steel, John, Pérez, Daniel R, Steel, J., Steel John, García-Sastre Adolfo, Manicassamy, B., Mirco Schmolke, Lindomar Pena, Benjamin G Hale, Schmolke, Mirco, Varga, Z.T., Schmolke Mirco   +42 more
core   +2 more sources

Higher titers of some H5N1 and recent human H1N1 and H3N2 influenza viruses in Mv1 Lu vs. MDCK cells

Virology Journal, 2011
Background The infectivity of influenza A viruses can differ among the various primary cells and continuous cell lines used for such measurements. Over many years, we observed that all things equal, the cytopathic effects caused by influenza A subtype ...
Daniels Deirdre E, Morrissey Jane M, O'Dowd Maureen K, Wahlgren Brett T, Wyatt Diane E, Hamilton Sara B, Lednicky John A   +6 more
doaj   +1 more source

Immunogenicity of a Multi-Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness. [PDF]

Influenza Other Respir Viruses
ABSTRACT Background The emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by the 2009 swine flu pandemic and the ongoing threat of an H5N1 avian flu pandemic.
Rikhi N, Sei CJ, Fraser KA, Muema K, Assiaw-Dufu A, Schuman RF, Fischer GW.   +6 more
europepmc   +2 more sources

A Single Immunization with Soluble Recombinant Trimeric Hemagglutinin Protects Chickens against Highly Pathogenic Avian Influenza Virus H5N1 [PDF]

, 2010
Background: The highly pathogenic avian influenza (HPAI) virus H5N1 causes multi-organ disease and death in poultry, resulting in significant economic losses in the poultry industry.
Dep Infectieziekten Immunologie, Robert P de Vries, Vries, R.P., de, Rigter, A., Rottier, P.J.M., Cornelissen, A.H.M., de Vries, R.P., Cornelissen, L.A.H.M., Alan Rigter, Cornelis A M de Haan, Strategic Infection Biology, de Haan, C.A.M., Haan, C.A.M., de, de Boer-Luijtze, E.A., Boer-Luijtze, E.A., de, Lisette A H M Cornelissen, Els A de Boer-Luijtze, Peter J M Rottier   +17 more
core   +3 more sources

Purification of neuraminidase from Influenza virus subtype H5N1

Jurnal Ilmu Ternak dan Veteriner, 2013
Influenza-virus neuraminidase plays vital role in the survival of the organisms. Vaccination of animals with this glycoprotein confers immune responses so that enable it to protect the animals from incoming infection. Supplementation of conventional vaccines with this glycoprotein increases the protection and longevity of the vaccine.
Simson Tarigan, Risa Indryani, Darminto ., Jagoda Ignjatovic   +3 more
openaire   +1 more source

Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells [PDF]

, 2008
Background: The hemagglutinin (HA) glycoprotein is the principal target of protective humoral immune responses to influenza virus infections but such antibody responses only provide efficient protection against a narrow spectrum of HA antigenic variants ...
Poon Leo L. M., Carsetti Rita, van der Meulen, J., Cinatl, J, Cox Freek, Guan, Yi, Ignace Lasters, Brink, Edward van den, van Deventer, W.B.E., Jongeneelen, M, ter Meulen Jan, Edward van den Brink, de Kruijf, C.G., de Kruif John, van Deventer, Els, Cinatl Jindrich, van Deventer, E, Peiris, M, Jaap Goudsmit, Carsetti, Rita, Throsby, Mark, Carsetti, R., Leo L M Poon, Cornelissen, L., Arjen Bakker, Kruijf, C.G., de, Throsby Mark, Lasters, I., Rita Carsetti, de Kruif, J, van den Brink, E., Poon, L.L.M., Freek Cox, Yi Guan, Goudsmit, J., Lisette Cornelissen, Els van Deventer, Cornelissen Lisette, de Kruif, John, Jongeneelen Mandy, Alard Philippe, Goudsmit Jaap, Guan Yi, Guan, Y, Alard, P., Brink, E., van den, ter Meulen, Jan, Peiris Malik, Deventer, Els van, Kruif, John de, Cinatl, J., John de Kruif, Jan ter Meulen, Cornelissen, L, Cox, F, Cox, Freek, Goudsmit, J, Cox, F., Poon, LLM, Bakker, A.B.H., Jindrich Cinatl, Lasters, Ignace, Jongeneelen, M., van Deventer Els, Mandy Jongeneelen, Poon, Leo L. M., Meulen, J., van der, Bakker, Arjen, Cinatl, Jindrich, van den Brink, E, Malik Peiris, Peiris, Malik, van den Brink Edward, Deventer, W.B.E., van, Bakker, A, van den Brink, Edward, Bakker Arjen, Mark Throsby, Throsby, M., Lasters, I, Guan, Y., Alard, Philippe, ter Meulen, J, Carsetti, R, Philippe Alard, Cornelissen, Lisette, Goudsmit, Jaap, Jongeneelen, Mandy, Peiris, M., Throsby, M, Meulen, Jan ter, Alard, P, Lasters Ignace   +92 more
core   +1 more source

Blood Screening for Influenza

Emerging Infectious Diseases, 2007
Influenza viruses, including highly pathogenic avian influenza virus (H5N1), could threaten blood safety. We analyzed 10,272 blood donor samples with a minipool nucleic acid amplication technique.
Michael Kai Hourfar, Anna Themann, Markus Eickmann, Pilaipan Puthavathana, Thomas Laue, Erhard Seifried, Michael Schmidt   +6 more
doaj   +1 more source