Results 11 to 20 of about 12,863 (219)

The Protective Effects of the A/ZJU01/ PR8/2013 Split H7N9 Avian Influenza Vaccine Against Highly Pathogenic H7N9 in BALB/c Mice

Cellular Physiology and Biochemistry, 2018
Background/Aims: Since the first case of novel H7N9 infection was reported, China has experienced five epidemics of H7N9. During the fifth wave, a highly pathogenic H7N9 strain emerged. In order to assess whether the H7N9 vaccine based on A/Zhejiang/DTID-
Xiao-Xin Wu, Xi-Long Deng, Dong-Shan Yu, Wei Yao, Hui-Lin Ou, Tian-Hao Weng, Chen-Yu Hu, Feng-Yu Hu, Nan-Ping Wu, Hangping Yao, Fu-Chun Zhang, Lan-Juan Li   +11 more
doaj   +3 more sources

Early responses to H7N9 in southern Mainland China [PDF]

BMC Infectious Diseases, 2014
H7N9 posed potentially serious health challenges for Chinese society. The previous SARS outbreak in this country was accompanied by contradictory information, while worries about wide-spread influenza led to discrimination worldwide. Early understanding of public threat perceptions is therefore important for effective public health communication and ...
Goodwin, R, Sun, S
openaire   +6 more sources

Immune Enhancement by the Tetra-Peptide Hydrogel as a Promising Adjuvant for an H7N9 Vaccine against Highly Pathogenic H7N9 Virus

Vaccines, 2022
Background: Short peptide hydrogel was reported as a possible adjuvant for vaccines. In order to evaluate whether the Tetra-Peptide Hydrogel can be a promising adjuvant for an H7N9 vaccine against the highly pathogenic H7N9 virus, we conducted this study.
Xiaoxin Wu, Songjia Tang, Zhehua Wang, Xiaoyun Ma, Lingjian Zhang, Fen Zhang, Lanlan Xiao, Shuai Zhao, Qian Li, Ying Wang, Qingjing Wang, Keda Chen   +11 more
doaj   +2 more sources

Risk assessment of the newly emerged H7N9 avian influenza viruses

Emerging Microbes and Infections, 2023
Since the first human case in 2013, H7N9 avian influenza viruses (AIVs) have caused more than 1500 human infections with a mortality rate of approximately 40%.
Pengxiang Chang, Jean-Remy Sadeyen, Sushant Bhat, Rebecca Daines, Altaf Hussain, Huseyin Yilmaz, Munir Iqbal   +6 more
doaj   +2 more sources

A live attenuated vaccine prevents replication and transmission of H7N9 highly pathogenic influenza viruses in mammals

Emerging Microbes and Infections, 2018
H7N9 influenza viruses emerged in 2013 and have caused severe disease and deaths in humans in China. Some H7N9 viruses circulating in chickens have mutated to highly pathogenic viruses that have caused several disease outbreaks in chickens.
Wenyu Yang, Xin Yin, Lizheng Guan, Mei Li, Shujie Ma, Jianzhong Shi, Guohua Deng, Yasuo Suzuki, Hualan Chen   +8 more
doaj   +2 more sources

Pathogenicity of the Novel A/H7N9 Influenza Virus in Mice

mBio, 2013
A novel avian-origin influenza A/H7N9 virus infecting humans was first identified in March 2013 and, as of 30 May 2013, has caused 132 human infections leading to 33 deaths.
Chris Ka Pun Mok, Horace Hok Yeung Lee, Michael Chi Wai Chan, Sin Fun Sia, Maxime Lestra, John Malcolm Nicholls, Huachen Zhu, Yi Guan, Joseph Malik Sriyal Peiris   +8 more
doaj   +2 more sources

Effectiveness of Whole, Inactivated, Low Pathogenicity Influenza A(H7N9) Vaccine against Antigenically Distinct, Highly Pathogenic H7N9 Virus

Emerging Infectious Diseases, 2018
The recent emergence of highly pathogenic influenza A(H7N9) variants poses a great risk to humans. We show that ferrets vaccinated with low pathogenicity H7N9 virus vaccine do not develop severe symptoms after infection with an antigenically distinct ...
Masato Hatta, Gongxun Zhong, Shiho Chiba, Tiago J.S. Lopes, Gabriele Neumann, Yoshihiro Kawaoka   +5 more
doaj   +2 more sources

Comparative Pathogenicity and Transmissibility of the H7N9 Highly Pathogenic Avian Influenza Virus and the H7N9 Low Pathogenic Avian Influenza Virus in Chickens

Viruses, 2019
There were five outbreaks of H7N9 influenza virus in humans in China since it emerged in 2013, infecting >1000 people. The H7N9 low pathogenic influenza virus was inserted into four amino acids in the HA protein cleavage site to mutate into the H7N9 ...
Hao Yu, Kunpeng Zhang, Xumeng Ye, Wenqing Wang, Wenbo Wu, Xia Wang, Yun Guan, Zhuoliang He, Yong Wang, Peirong Jiao   +9 more
doaj   +2 more sources

Comparative effectiveness of H7N9 vaccines in healthy individuals

Human Vaccines & Immunotherapeutics, 2019
Background: Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 vaccines have been completed.
Dan Zheng, Feixia Gao, Cheng Zhao, Yahong Ding, Yemin Cao, Tianhan Yang, Xuesong Xu, Ze Chen   +7 more
doaj   +2 more sources

Saliva as a source of reagent to study human susceptibility to avian influenza H7N9 virus infection

Emerging Microbes and Infections, 2018
Avian influenza H7N9 viruses are an important public health concern due to their high mortality rate and potentials for future pandemics. We investigated human susceptibility to H7N9 viruses using recombinant H7N9 hemagglutinin (HA) proteins as a probe ...
Ming Tan, Lunbiao Cui, Xiang Huo, Ming Xia, Fengjuan Shi, Xiaoyan Zeng, Pengwei Huang, Weiming Zhong, Weiwei Li, Ke Xu, Liling Chen, Minghao Zhou, Xi Jiang   +12 more
doaj   +2 more sources