Results 1 to 10 of about 114,195,449 (202)

A System Based-Approach to Examine Host Response during Infection with Influenza A Virus Subtype H7N9 in Human and Avian Cells [PDF]

Cells, 2020
Although the influenza A virus H7N9 subtype circulates within several avian species, it can also infect humans with a severe disease outcome. To better understand the biology of the H7N9 virus we examined the host response to infection in avian and human
Hui Chen, Boon Huan Tan, Biruhalem Taye   +2 more
exaly   +6 more sources

Virus subtype-specific suppression of MAVS aggregation and activation by PB1-F2 protein of influenza A (H7N9) virus

PLoS Pathogens, 2020
Human infection with avian influenza A (H5N1) and (H7N9) viruses causes severe respiratory diseases. PB1-F2 protein is a critical virulence factor that suppresses early type I interferon response, but the mechanism of its action in relation to high ...
Honglin Chen, Chi Ping Chan, Kwok-Yung Yuen   +2 more
exaly   +5 more sources

Accelerated Evolution of H7N9 Subtype Influenza Virus under Vaccination Pressure [PDF]

Virologica Sinica, 2021
No avian H7N9 outbreaks have occurred since the introduction of H7N9 inactivated vaccine in the fall of 2017. However, H7N9 is still prevalent in poultry. To surveil the prevalence, genetic characteristics, and antigenic changes of H7N9, over 7000 oropharyngeal and cloaca swab specimens were collected from live poultry markets and farms in 15 provinces
Yifan Wu, Weixin Jia, Wenbao Qi
exaly   +3 more sources

Development of an Inactivated H7N9 Subtype Avian Influenza Serological DIVA Vaccine Using the Chimeric HA Epitope Approach

Microbiology Spectrum, 2021
H7N9 avian influenza virus (AIV) is an emerging zoonotic pathogen, and it is necessary to develop a differentiating infected from vaccinated animals (DIVA) vaccine for the purpose of eradication. H7N9 subtype AIV hemagglutinin subunit 2 glycoprotein (HA2)
Daxin Peng, Juan Li, Tao Qin
exaly   +3 more sources

Visual detection of human infection with influenza A (H7N9) virus by subtype-specific reverse transcription loop-mediated isothermal amplification with hydroxynaphthol blue dye [PDF]

Clinical Microbiology and Infection, 2013
A rapid and sensitive H7 and N9 subtype-specific reverse transcription loop-mediated isothermal amplification assay was developed respectively for visual detection of human-infected influenza A (H7N9) virus. The reaction was performed in one step in a single tube at 63°C for 60 min with the addition of hydroxynaphthol blue dye before amplification. The
Xiong Ding
exaly   +3 more sources

Cardiac complications associated with the influenza viruses A subtype H7N9 or pandemic H1N1 in critically ill patients under intensive care

Brazilian Journal of Infectious Diseases, 2017
Background and objective: The clinical presentations and disease courses of patients hospitalized with either influenza A virus subtype H7N9 (H7N9) or 2009 pandemic H1N1 influenza virus were compared in a recent report, but associated cardiac ...
Jiajia Wang, Xinjing Yang
exaly   +3 more sources

Development of Rapid Immunochromatographic Test for Hemagglutinin Antigen of H7 Subtype in Patients Infected with Novel Avian Influenza A (H7N9) Virus

PLoS ONE, 2014
Since human infection with the novel H7N9 avian influenza virus was identified in China in March 2013, the relatively high mortality rate and possibility of human-to-human transmission have highlighted the urgent need for sensitive and specific assays for diagnosis of H7N9 infection.We developed a rapid diagnostic test for the novel avian influenza A ...
Xiao-Chun Luo, Cheng-Feng Qin, Emmanuel Enoch Dzakah   +2 more
exaly   +5 more sources

Prior immunity to seasonal influenza A(H3N2) virus confers varying levels of cross-protection against challenge with clade 2.3.4.4b A(H5N1), A(H7N9), or A(H9N2) virus in a ferret model [PDF]

Microbiology Spectrum
Evaluating how prior immunity to seasonal influenza viruses influences subsequent zoonotic influenza A virus (IAV) infection in animal models is critical for pandemic preparedness.
Xiangjie Sun, Jessica A. Belser, Zhu-Nan Li, Feng Liu, Nicole Brock, Joanna A. Pulit-Penaloza, Troy J. Kieran, Claudia Pappas, Hui Zeng, Jessie C. Chang, Paul J. Carney, Brandon L. Bradley-Ferrell, James Stevens, Min Z. Levine, Terrence M. Tumpey, Taronna R. Maines   +15 more
doaj   +2 more sources

Direct airway delivery of a humanized anti-H7N9 neutralizing antibody broadly protects against divergent H7 influenza viruses in the mouse model [PDF]

Journal of Virology
Passive administration of broadly neutralizing anti-influenza monoclonal antibodies (mAbs) before or after virus infection can prevent or alleviate disease.
Wang Yu, Xiaozheng He, Jiangyan Zhao, Yunlong Dou, Tingyu Hu, Xia Chen, Xuran Ma, Xiaoquan Wang, Shunlin Hu, Jiao Hu, Xiufan Liu, Zenglei Hu   +11 more
doaj   +2 more sources

A cross-sectional study of avian influenza in one district of Guangzhou, 2013. [PDF]

PLoS ONE, 2014
Since Feb, 2013, more than 100 human beings had been infected with novel H7N9 avian influenza virus. As of May 2013, several H7N9 viruses had been found in retail live bird markets (LBMs) in Guangdong province of southern China where several human cases ...
Haiming Zhang, Cong Peng, Xiaodong Duan, Dan Shen, Guanghua Lan, Wutao Xiao, Hai Tan, Ling Wang, Jialei Hou, Jiancui Zhu, Riwen He, Haibing Zhang, Lilan Zheng, Jianyu Yang, Zhen Zhang, Zhiwei Zhou, Wenhua Li, Mailing Hu, Jinhui Zhong, Yuhua Chen   +19 more
doaj   +1 more source