Results 41 to 50 of about 114,195,449 (202)

The Dynamics of the Ferret Immune Response During H7N9 Influenza Virus Infection

Frontiers in Immunology, 2020
As the recent outbreak of SARS-CoV-2 has highlighted, the threat of a pandemic event from zoonotic viruses, such as the deadly influenza A/H7N9 virus subtype, continues to be a major global health concern.
William S. J. Horman, William S. J. Horman, Thi H. O. Nguyen, Katherine Kedzierska, Jeffrey Butler, Songhua Shan, Rachel Layton, John Bingham, Jean Payne, Andrew G. D. Bean, Daniel S. Layton   +10 more
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Use of fractional factorial design to study the compatibility of viral ribonucleoprotein gene segments of human H7N9 virus and circulating human influenza subtypes [PDF]

Influenza and Other Respiratory Viruses, 2014
Avian H7N9 influenza viruses may pose a further threat to humans by reassortment with human viruses, which could lead to generation of novel reassortants with enhanced polymerase activity. We previously established a novel statistical approach to study the polymerase activity of reassorted vRNPs (Influenza Other Respir Viruses. 2013;7:969‐78). Here, we
Chin, AWH, Mok, CKP, Zhu, H, Poon, LLM, Peiris, JSM, Guan, Y   +5 more
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Infection with Possible Precursor of Avian Influenza A(H7N9) Virus in a Child, China, 2013

Emerging Infectious Diseases, 2014
During the early stage of the avian influenza A(H7N9) epidemic in China in March 2013, a strain of the virus was identified in a 4-year-old boy with mild influenza symptoms.
Lili Ren, Xuelian Yu, Baihui Zhao, Fan Wu, Qi Jin, Xi Zhang, Jianwei Wang   +6 more
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Virus Adaptation Following Experimental Infection of Chickens with a Domestic Duck Low Pathogenic Avian Influenza Isolate from the 2017 USA H7N9 Outbreak Identifies Polymorphic Mutations in Multiple Gene Segments

Viruses, 2021
In March 2017, highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) subtype H7N9 were detected from poultry farms and backyard birds in several states in the southeast United States.
Klaudia Chrzastek, Karen Segovia, Mia Torchetti, Mary Lee Killian, Mary Pantin-Jackwood, Darrell R. Kapczynski   +5 more
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Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells [PDF]

, 2008
Background: The hemagglutinin (HA) glycoprotein is the principal target of protective humoral immune responses to influenza virus infections but such antibody responses only provide efficient protection against a narrow spectrum of HA antigenic variants ...
Poon Leo L. M., Carsetti Rita, van der Meulen, J., Cinatl, J, Cox Freek, Guan, Yi, Ignace Lasters, Brink, Edward van den, van Deventer, W.B.E., Jongeneelen, M, ter Meulen Jan, Edward van den Brink, de Kruijf, C.G., de Kruif John, van Deventer, Els, Cinatl Jindrich, van Deventer, E, Peiris, M, Jaap Goudsmit, Carsetti, Rita, Throsby, Mark, Carsetti, R., Leo L M Poon, Cornelissen, L., Arjen Bakker, Kruijf, C.G., de, Throsby Mark, Lasters, I., Rita Carsetti, de Kruif, J, van den Brink, E., Poon, L.L.M., Freek Cox, Yi Guan, Goudsmit, J., Lisette Cornelissen, Els van Deventer, Cornelissen Lisette, de Kruif, John, Jongeneelen Mandy, Alard Philippe, Goudsmit Jaap, Guan Yi, Guan, Y, Alard, P., Brink, E., van den, ter Meulen, Jan, Peiris Malik, Deventer, Els van, Kruif, John de, Cinatl, J., John de Kruif, Jan ter Meulen, Cornelissen, L, Cox, F, Cox, Freek, Goudsmit, J, Cox, F., Poon, LLM, Bakker, A.B.H., Jindrich Cinatl, Lasters, Ignace, Jongeneelen, M., van Deventer Els, Mandy Jongeneelen, Poon, Leo L. M., Meulen, J., van der, Bakker, Arjen, Cinatl, Jindrich, van den Brink, E, Malik Peiris, Peiris, Malik, van den Brink Edward, Deventer, W.B.E., van, Bakker, A, van den Brink, Edward, Bakker Arjen, Mark Throsby, Throsby, M., Lasters, I, Guan, Y., Alard, Philippe, ter Meulen, J, Carsetti, R, Philippe Alard, Cornelissen, Lisette, Goudsmit, Jaap, Jongeneelen, Mandy, Peiris, M., Throsby, M, Meulen, Jan ter, Alard, P, Lasters Ignace   +92 more
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Surveillance and response systems for elimination of tropical diseases : summary of a thematic series in infectious diseases of poverty [PDF]

, 2016
The peer-reviewed journal Infectious Diseases of Poverty provides a new platform to engage with, and disseminate in an open-access format, science outside traditional disciplinary boundaries.
Zhou, Xiao-Nong, Xiao-Nong Zhou (92570), Yap, Peiling, Utzinger, Jürg, Robert Bergquist (377449), Xia Zhou (291729), Zhou, Xia, Bergquist, Robert, Peiling Yap (596280), Marcel Tanner (33894), JĂźrg Utzinger (3428396), Tanner, Marcel   +11 more
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Cocirculation of Three Hemagglutinin and Two Neuraminidase Subtypes of Avian Influenza Viruses in Huzhou, China, April 2013: Implication for the Origin of the Novel H7N9 Virus [PDF]

Journal of Virology, 2014
ABSTRACT We detected three avian influenza hemagglutinin (HA) subtypes (H7, H9, and H5) and two neuraminidase (NA) subtypes (N9 and N2), as well as H7N9-related H9N9 reassortant intermediates, cocirculating among poultry in Huzhou, China, during April 2013.
Jiankang, Han, Lili, Wang, Jia, Liu, Meihua, Jin, Fangyuan, Hao, Peng, Zhang, Zhao, Zhang, Dong, Wen, Xiaofang, Wu, Guangtao, Liu, Lei, Ji, Deshun, Xu, Dongming, Zhou, Qibin, Leng, Ke, Lan, Chiyu, Zhang   +15 more
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Simultaneous detection of influenza A subtypes of H3N2 virus, pandemic (H1N1) 2009 virus and reassortant avian H7N9 virus in humans by multiplex one-step real-time RT-PCR assay [PDF]

SpringerPlus, 2016
Influenza A virus is a leading causative pathogen of human acute respiratory infection. Recently, the co-circulation of pandemic (H1N1) 2009 and seasonal H3N2 viruses was reported, and sporadic cases with reassortant avian H7N9 virus are continually reported in China. We aimed to establish a multiplex one-step real-time reverse transcription-polymerase
Cui, Dawei, Zhao, Dejian, Xie, Guoliang, Yang, Xianzhi, Huo, Zhaoxia, Zheng, Shufa, Yu, Fei, Chen, Yu   +7 more
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An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response [PDF]

, 2014
Influenza A viruses counteract the cellular innate immune response at several steps, including blocking RIG I-dependent activation of interferon (IFN) transcription, IFN-dependent upregulation of IFN-stimulated genes (ISGs) and the activity of various ...
Fernández, Yolanda, Oliveros, JC, Randall, Richard E, Asensio, Víctor J, Killip, Marian J., Randall, RE, Oliveros, Juan Carlos, Killip, Marian J, Asensio, Víctor J., Bengoechea, Jose Antonio, Oliveros, Juan C., Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Bengoechea, JA, Bengoechea, José A; id_orcid, Ortín, Juan, Killip, MJ, Ortín, J, Asensio, Víctor José, Randall, Richard E., Bengoechea, José A., Asensio, VJ, Oliveros, Juan C, Fernández, Y   +23 more
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The transmembrane replacement H7N9-VLP vaccine displays high levels of protection in mice

Frontiers in Microbiology, 2022
The incidence of infections caused by the H7N9 subtype of the influenza virus has expanded rapidly in China in recent decades, generating massive economic loss and posing a significant threat to public health.
Jianru Qin, Bing Hu, Qiqi Song, Ruijuan Wang, Xiangfei Zhang, Yaqi Yu, Jian-Hua Wang   +6 more
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