Results 21 to 30 of about 114,195,449 (202)

AS03-adjuvanted H7N9 inactivated split virion vaccines induce cross-reactive and protective responses in ferrets

npj Vaccines, 2021
Human infections with avian H7N9 subtype influenza viruses are a major public health concern and vaccines against H7N9 are urgently needed for pandemic preparedness.
Daniel Stadlbauer, Leon de Waal, Edith Beaulieu, Shirin Strohmeier, Edwin J. B. Veldhuis Kroeze, Philippe Boutet, Albert D. M. E. Osterhaus, Florian Krammer, Bruce L. Innis, Raffael Nachbagauer, Koert J. Stittelaar, Corey P. Mallett   +11 more
doaj   +1 more source

Avian-to-Human Receptor-Binding Adaptation of Avian H7N9 Influenza Virus Hemagglutinin

Cell Reports, 2019
Summary: Since 2013, H7N9 avian influenza viruses (AIVs) have caused more than 1,600 human infections, posing a threat to public health. An emerging concern is whether H7N9 AIVs will cause pandemics among humans. Molecular analysis of hemagglutinin (HA),
Ying Xu, Ruchao Peng, Wei Zhang, Jianxun Qi, Hao Song, Sheng Liu, Haiyuan Wang, Min Wang, Haixia Xiao, Lifeng Fu, Zheng Fan, Yuhai Bi, Jinghua Yan, Yi Shi, George F. Gao   +14 more
doaj   +1 more source

Development of a Reverse Transcription Loop-Mediated Isothermal Amplification Method for the Rapid Detection of Subtype H7N9 Avian Influenza Virus [PDF]

BioMed Research International, 2014
A novel influenza A (H7N9) virus has emerged in China. To rapidly detect this virus from clinical samples, we developed a reverse transcription loop-mediated isothermal amplification (RT-LAMP) method for the detection of the H7N9 virus. The minimum detection limit of the RT-LAMP assay was 0.01 PFU H7N9 virus, making this method 100-fold more sensitive ...
Bao, Hongmei, Zhao, Yuhui, Wang, Yunhe, Xu, Xiaolong, Shi, Jianzhong, Zeng, Xianying, Wang, Xiurong, Chen, Hualan   +7 more
openaire   +2 more sources

Single Dose of Bivalent H5 and H7 Influenza Virus-Like Particle Protects Chickens Against Highly Pathogenic H5N1 and H7N9 Avian Influenza Viruses

Frontiers in Veterinary Science, 2021
Both H5N1 and H7N9 subtype avian influenza viruses cause enormous economic losses and pose considerable threats to public health. Bivalent vaccines against both two subtypes are more effective in control of H5N1 and H7N9 viruses in poultry and novel egg ...
Jiao Hu, Jiao Hu, Jiao Hu, Peipei Peng, Peipei Peng, Peipei Peng, Jun Li, Jun Li, Jun Li, Qi Zhang, Qi Zhang, Qi Zhang, Rumeng Li, Rumeng Li, Rumeng Li, Xiaoquan Wang, Xiaoquan Wang, Xiaoquan Wang, Min Gu, Min Gu, Min Gu, Zenglei Hu, Zenglei Hu, Zenglei Hu, Shunlin Hu, Shunlin Hu, Shunlin Hu, Xiaowen Liu, Xiaowen Liu, Xiaowen Liu, Xinan Jiao, Xinan Jiao, Daxin Peng, Daxin Peng, Daxin Peng, Xiufan Liu, Xiufan Liu, Xiufan Liu   +37 more
doaj   +1 more source

Avian Influenza A(H7N9) Virus Infection in 2 Travelers Returning from China to Canada, January 2015

Emerging Infectious Diseases, 2016
In January 2015, British Columbia, Canada, reported avian influenza A(H7N9) virus infection in 2 travelers returning from China who sought outpatient care for typical influenza-like illness.
Danuta Skowronski, Catharine Chambers, Reka Gustafson, Dale B. Purych, Patrick Tang, Nathalie Bastien, Mel Krajden, Yan Li   +7 more
doaj   +1 more source

Characterization of Humoral Responses Induced by an H7N9 Influenza Virus-Like Particle Vaccine in BALB/C Mice

Viruses, 2015
In April 2013, human infections with a novel avian influenza (H7N9) virus emerged in China. It has caused serious concerns for public health throughout the world.
Li Zhang, Jing Lu, Yin Chen, Fengjuan Shi, Huiyan Yu, Chao Huang, Lunbiao Cui, Zhiyang Shi, Yongjun Jiao, Yuemei Hu   +9 more
doaj   +1 more source

An Investigational Antiviral Drug, DAS181, Effectively Inhibits Replication of Zoonotic Influenza A Virus Subtype H7N9 and Protects Mice From Lethality [PDF]

The Journal of Infectious Diseases, 2014
Human infections caused by avian influenza A virus type subtype H7N9 have been associated with substantial morbidity and mortality. Emergence of virus variants carrying markers of decreased susceptibility to neuraminidase inhibitors was reported.
Marjuki, Henju, Mishin, Vasiliy P., Chesnokov, Anton P., De La Cruz, Juan A., Fry, Alicia M., Villanueva, Julie, Gubareva, Larisa V.   +6 more
openaire   +2 more sources

Development of an Influenza Rapid Diagnostic Kit Specific for the H7 Subtype

Frontiers in Microbiology, 2018
Since the spring of 2013, human infections with H7N9 viruses have been detected in China. Some of these viruses have become highly pathogenic. Highly and low pathogenic avian influenza H7N9 viruses are currently co-circulating with the seasonal influenza
Kiyoko Iwatsuki-Horimoto, Jianzhong Shi, Xiurong Wang, Yuko Sakai-Tagawa, Mutsumi Ito, Kazushi Murakami, Tiago J. da Silva Lopes, Tiago J. da Silva Lopes, Kazunari Nakaishi, Seiya Yamayoshi, Satoshi Watabe, Hualan Chen, Yoshihiro Kawaoka, Yoshihiro Kawaoka, Yoshihiro Kawaoka   +14 more
doaj   +1 more source

Early responses to H7N9 in southern mainland China [PDF]

, 2014
This article is made available through the Brunel Open Access Publishing Fund. © 2014 Goodwin and Sun; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http ...
Sun, S, Goodwin, R, Shaojing Sun, Robin Goodwin   +3 more
core   +2 more sources

A Replication-Defective Influenza Virus Vaccine Confers Complete Protection against H7N9 Viral Infection in Mice

, 2020
Avian influenza H7N9 viruses continue to pose a great threat to public health, which is evident by their high case-fatality rates. Although H7N9 was first isolated in humans in China in 2013, to date, there is no commercial vaccine available against this
Kannupriya Pandey, Yan Zhou, Yao Lu, Shelby Landreth   +3 more
core   +1 more source