Results 51 to 60 of about 10,711 (202)

Simultaneous detection of influenza A subtypes of H3N2 virus, pandemic (H1N1) 2009 virus and reassortant avian H7N9 virus in humans by multiplex one-step real-time RT-PCR assay [PDF]

SpringerPlus, 2016
Influenza A virus is a leading causative pathogen of human acute respiratory infection. Recently, the co-circulation of pandemic (H1N1) 2009 and seasonal H3N2 viruses was reported, and sporadic cases with reassortant avian H7N9 virus are continually reported in China. We aimed to establish a multiplex one-step real-time reverse transcription-polymerase
Cui, Dawei, Zhao, Dejian, Xie, Guoliang, Yang, Xianzhi, Huo, Zhaoxia, Zheng, Shufa, Yu, Fei, Chen, Yu   +7 more
openaire   +2 more sources

Virus Adaptation Following Experimental Infection of Chickens with a Domestic Duck Low Pathogenic Avian Influenza Isolate from the 2017 USA H7N9 Outbreak Identifies Polymorphic Mutations in Multiple Gene Segments

Viruses, 2021
In March 2017, highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) subtype H7N9 were detected from poultry farms and backyard birds in several states in the southeast United States.
Klaudia Chrzastek, Karen Segovia, Mia Torchetti, Mary Lee Killian, Mary Pantin-Jackwood, Darrell R. Kapczynski   +5 more
doaj   +1 more source

Characterization of a reassortant H11N9 subtype avian influenza virus isolated from spot-billed duck in China

Virus genes, 2023
H11N9 viruses in wild birds might have provided the NA gene of human H7N9 virus in early 2013 in China, which evolved with highly pathogenic strains in 2017 and caused severe fatalities.
Bo Wang, Yanyi Huang, Bin Hu, Heng-jiao Zhang, Shuyi Han, Ziwen Yang, Qianqian Su, Hongxuan He   +7 more
semanticscholar   +1 more source

The transmembrane replacement H7N9-VLP vaccine displays high levels of protection in mice

Frontiers in Microbiology, 2022
The incidence of infections caused by the H7N9 subtype of the influenza virus has expanded rapidly in China in recent decades, generating massive economic loss and posing a significant threat to public health.
Jianru Qin, Bing Hu, Qiqi Song, Ruijuan Wang, Xiangfei Zhang, Yaqi Yu, Jian-Hua Wang   +6 more
doaj   +1 more source

Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle

PLoS Pathogens, 2022
Annual influenza vaccination is recommended to update the variable hemagglutinin antigens. Here, we first designed a virus-like particle (VLP) displaying consensus multi-neuraminidase (NA) subtypes (cN1, cN2, B cNA) and M2 ectodomain (M2e) tandem repeat (
Ki-hye Kim, Zhuo Li, Noopur Bhatnagar, Jeeva Subbiah, Bo Ryoung Park, C. Shin, P. Pushko, Bao-Zhong Wang, Sang-Moo Kang   +8 more
semanticscholar   +1 more source

Enhancing Immune Response and Heterosubtypic Protection Ability of Inactivated H7N9 Vaccine by Using STING Agonist as a Mucosal Adjuvant

Frontiers in Immunology, 2019
Influenza vaccines for H7N9 subtype have shown low immunogenicity in human clinical trials. Using novel adjuvants might represent the optimal available option in vaccine development.
Jian Luo, Jian Luo, Xu-ping Liu, Fei-fei Xiong, Fei-xia Gao, Ying-lei Yi, Min Zhang, Ze Chen, Wen-song Tan   +8 more
doaj   +1 more source

The diversity of avian influenza virus subtypes in live poultry markets before and during the second wave of A(H7N9) infections in Hangzhou, China

Emerging Microbes & Infections, 2015
The diversity of avian influenza virus subtypes in live poultry markets before and during the second wave of A(H7N9) infections in Hangzhou ...
Li, Jun, Yu, Xinfen, Pu, Xiaoying, Yang, Xuhui, Kou, Yu, Zhou, Yinyan, Qian, Xin, Xie, Li, Pan, Jingcao   +8 more
openaire   +2 more sources

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

A field‐deployable insulated isothermal RT‐PCR assay for identification of influenza A (H7N9) shows good performance in the laboratory

, 2019
Background: Avian influenza A (H7N9) remains circulating in China. For countries at risk of introduction of H7N9, such as Vietnam, early detection of H7N9 virus is essential for the early containment of the virus.
Yun‐Long Tsai, Guan, Y, Hsin‐Jou Tseng, Pawin Padungtod, Inui, K, Simon Chung, Filip Claes, Ken Inui, ChuanFu Mark Tsai, Huachen Zhu, Chung, S, Zhu, H, Padungtod, P, Wantanee Kalpravidh, Tseng, HJ, Nguyen, T, Tung Nguyen, Tsai, CM, Claes, F, Yi Guan, Kalpravidh, W, Tsai, YL   +21 more
core   +1 more source

Human cytotoxic T lymphocytes directed to seasonal influenza A viruses cross-react with the newly emerging H7N9 virus

, 2014
In February 2013, zoonotic transmission of a novel influenza A virus of the H7N9 subtype was reported in China. Although at present no sustained human-to-human transmission has been reported, a pandemic outbreak of this H7N9 virus is feared.
Albert D. M. E. Osterhaus, Vogelzang-van Trierum, S.E. (Stella ), Osterhaus, A.D.M.E. (Albert), Gerrie de Mutsert, Ron A. M. Fouchier, Carolien E. van de Sandt, Martina M. Geelhoed-Mieras, Fouchier, R.A.M. (Ron), Marine L. B. Hillaire, Hillaire, M.L.B. (Marine), Joost H. C. M. Kreijtz, Geelhoed-Mieras, M.M. (Martina), Guus F. Rimmelzwaan, Kreijtz, J.H.C.M. (Joost), Sandt, C.E. (Carolien) van de, Stella E. Vogelzang-van Trierum, Rimmelzwaan, G.F. (Guus), Mutsert, G. (Gerrie) de   +17 more
core   +2 more sources