Results 31 to 40 of about 12,863 (219)

Influenza A (H7N9) and the Importance of Digital Epidemiology [PDF]

New England Journal of Medicine, 2013
In recent outbreaks including that of novel H7N9 influenza, digital disease surveillance has supplemented laboratory studies and work by public health officials and epidemiologists, by leveraging widespread use of the Internet, mobile phones, and social media.
Marcel, Salathé, Clark C, Freifeld, Sumiko R, Mekaru, Anna F, Tomasulo, John S, Brownstein   +4 more
openaire   +2 more sources

Anti-H7N9 avian influenza A virus activity of interferon in pseudostratified human airway epithelium cell cultures

Virology Journal, 2019
Background Since H7N9 influenza A virus (H7N9) was first reported in 2013, five waves of outbreaks have occurred, posing a huge threat to human health.
Ai-jun Chen, Jie Dong, Xin-hui Yuan, Hong Bo, Shu-zhen Li, Chao Wang, Zhao-jun Duan, Li-shu Zheng   +7 more
doaj   +1 more source

T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response

Human Vaccines & Immunotherapeutics, 2018
The delayed availability of vaccine during the 2009 H1N1 influenza pandemic created a sense of urgency to better prepare for the next influenza pandemic.
Leonard Moise, Bethany M. Biron, Christine M. Boyle, Nese Kurt Yilmaz, Hyesun Jang, Celia Schiffer, Ted M. Ross, William D. Martin, Anne S. De Groot   +8 more
doaj   +1 more source

Transcriptome Differences in Normal Human Bronchial Epithelial Cells in Response to Influenza A pdmH1N1 or H7N9 Virus Infection

Cells, 2022
Avian influenza A (H7N9) virus infections frequently lead to acute respiratory distress syndrome and death in humans. The emergence of H7N9 virus infections is a serious public health threat.
Tzu-Hsuan Hsieh, Ya-Jhu Lin, Mei-Jen Hsioa, Hsin-Ju Wang, Lu-Ting Chen, Shu-Li Yang, Chung-Guei Huang   +6 more
doaj   +1 more source

H7N9 is a virus worth worrying about [PDF]

Nature, 2013
Warnings about the emergence of another influenza virus may elicit scepticism, but we should not be complacent, cautions Peter Horby.
Horby, P., Tatem, A.J., Huang, Z., Gilbert, M., Robinson, Timothy P., Wint, G.R.W., Hayden, F.G., Van Vinh Chau, N., Shindo, N., Carson, G., Gao, Z., Hongjie, Y., Hay, S.I., Farrar, J.   +13 more
openaire   +4 more sources

Prediction of H7N9 epidemic in China

Chinese Medical Journal, 2014
Background In March 2013, human cases of infection with a novel A (H7N9) influenza virus emerged in China. The epidemic spread quickly and as of 6 May 2013, there were 129 confirmed cases. The purpose of this study was to analyze the epidemiology of the confirmed cases, determine the impacts of bird migration and temperature ...
Zhaojie, Zhang, Yao, Xia, Yi, Lu, Jingchao, Yang, Luwen, Zhang, Hui, Su, Lili, Lin, Guoling, Wang, Tongmei, Wang, Shao, Lin, Zhongmin, Guo, Jiahai, Lu   +11 more
openaire   +2 more sources

Virological, Serological, and Antiviral Studies in an Imported Human Case of Avian Influenza A(H7N9) Virus in Taiwan

, 2017
We describe the clinical course and virological characteristics of the first H7N9 influenza case in a Taiwanese patient; this patient had detectable viruses in the airway for 2 weeks, during which time an oseltamivir resistance-associated R292K mutation ...
Lin, Pi-Han;Chao, Tai-Ling;Kuo, Shuenn-Wen;Wang, Jann-Tay;Hung, Chien-Ching;Lin, Huan-Chun;Yang, Zong-Yu;Ho, Shu-Yuan;Chang, Chun-Kai;Huang, Ming-Siang;Chen, Hui-Hou;Chen, Yee-Chun;Lai, Hong-Shiee;Chang, Sui-Yuan;Chang, Shan-Chwen;Yang, Pan-Chyr, 張上淳;楊泮池;陳宜君;洪健清;賴鴻緒;王振泰;郭順文;何淑媛;張淑媛   +1 more
core   +1 more source

Allosteric Neutralization by Human H7N9 Antibodies

, 2023
Abstract The avian influenza A virus H7N9 causes severe human infections with more than 30% fatality despite the use of neuraminidase inhibitors. Currently there is no H7N9-specific prevention or treatment for humans. From a 2013 H7N9 convalescent case occurred in Hong Kong, we isolated four H7 hemagglutinin (HA)-reactive monoclonal antibodies (
Xueling Wu, Manxue Jia, HanJun Zhao, Nicholas Morano, Hong Lu, Yin-Ming Lui, Haijuan Du, Jordan Becker, Kwok-Yung Yuen, David Ho, Peter Kwong, Lawrence Shapiro, Kelvin Kai-Wang To   +12 more
openaire   +2 more sources

Avian-Origin Influenza A(H7N9) Infection in Influenza A(H7N9)–Affected Areas of China: A Serological Study [PDF]

The Journal of Infectious Diseases, 2013
Serological surveillance conducted in areas of an outbreak of influenza A(H7N9) infection in China found no seropositivity for antibodies specific for avian-origin influenza A(H7N9) among 1129 individuals of the general population, whereas >6% of 396 poultry workers were positive (on the basis of a hemagglutination inhibition titer of ≥ 80) for this ...
Chen, Y, Yang, SG, Cui, DW, Yao, HP, Lou, JZ, Huo, ZX, Xie, GL, Yu, F, Zheng, SF, Yang, YD, Zhu, YX, Lu, XQ, Liu, XL, Lau, SY, Chan, JFW, To, KKW, Yuen, KY, Chen, H, Li, LJ   +18 more
openaire   +4 more sources

Entry properties and entry inhibitors of a human H7N9 influenza virus. [PDF]

PLoS ONE, 2014
The recently identified human infections with a novel avian influenza H7N9 virus in China raise important questions regarding possible risk to humans. However, the entry properties and tropism of this H7N9 virus were poorly understood.
Youhui Si, Jianguo Li, Yuqiang Niu, Xiuying Liu, Lili Ren, Li Guo, Min Cheng, Hongli Zhou, Jianwei Wang, Qi Jin, Wei Yang   +10 more
doaj   +1 more source