Results 51 to 60 of about 13,429 (224)

Treatment of Highly Pathogenic H7N9 Virus-Infected Mice with Baloxavir Marboxil

Viruses, 2019
Viral neuraminidase inhibitors show limited efficacy in mice infected with H7N9 influenza A viruses isolated from humans. Although baloxavir marboxil protected mice from lethal challenge infection with a low pathogenic avian influenza H7N9 virus isolated
Maki Kiso, Seiya Yamayoshi, Yuri Furusawa, Masaki Imai, Yoshihiro Kawaoka   +4 more
doaj   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

The pandemic threat of an Avian Influenza Virus: An overview

Journal of Zoonotic Diseases
The worst pandemic in modern history occurred during the 1918 H1N1 Spanish Influenza epidemic. Two additional instances of influenza A (H5N1) viral infection in humans have been disclosed to WHO in the West Pacific Zone between July 12 and July 18 ...
Amandeep Kaur, Ranjeet Kumar, Hardik Kumar, Sonakshi Garg, Dharmendra Kumar   +4 more
doaj   +1 more source

Platelet count and mortality of H7N9 infected patients in Guangdong, China

Platelets, 2020
Avian influenza A (H7N9) is a serve zoonosis with a high mortality rate. Timely and effective diagnosis and early warning is crucial for the clinical treatment of H7N9 patients. The previous studies indicated that thrombocytopenia was associated with the
Ying Chen, Yang Yang, Jian Cheng, Jiahai Lu, Wenbiao Hu   +4 more
doaj   +1 more source

Spatiotemporal Associations and Molecular Evolution of Highly Pathogenic Avian Influenza A H7N9 Virus in China from 2017 to 2021

Viruses, 2021
Highly pathogenic (HP) H7N9 avian influenza virus (AIV) emerged in China in 2016. HP H7N9 AIV caused at least 33 human infections and has been circulating in poultry farms continuously since wave 5.
Dongchang He, Min Gu, Xiyue Wang, Xiaoquan Wang, Gairu Li, Yayao Yan, Jinyuan Gu, Tiansong Zhan, Huiguang Wu, Xiaoli Hao, Guoqing Wang, Jiao Hu, Shunlin Hu, Xiaowen Liu, Shuo Su, Chan Ding, Xiufan Liu   +16 more
doaj   +1 more source

Management of H7N9 Bird Flu Case [PDF]

Respiratory Care, 2014
To the Editor: The report entitled “Management of the first confirmed case of avian influenza A H7N9” is very interesting. Qiao et al[1][1] reported that “when the viral infection was identified, strict procedures for disinfection and protection were carried out.” Basically, the ...
openaire   +2 more sources

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, Volume 7, Issue 5, October 2026.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

Computational Assay of H7N9 Influenza Neuraminidase Reveals R292K Mutation Reduces Drug Binding Affinity [PDF]

, 2013
The emergence of a novel H7N9 avian influenza that infects humans is a serious cause for concern. Of the genome sequences of H7N9 neuraminidase available, one contains a substitution of arginine to lysine at position 292, suggesting a potential for ...
Long, Benjamin J O, Mulholland, Adrian J., Woods, Christopher J, Malaisree, Maturos, McIntosh-Smith, Simon N   +4 more
core   +1 more source

Preparedness for Human Infections With Emerging Zoonotic Influenza Viruses: History, Continuing Risk, and the Need for Multisectoral Rapid Response Training

Influenza and Other Respiratory Viruses, Volume 20, Issue 10, October 2026.
ABSTRACT Since 1997, avian influenza A(H5) viruses have threatened human health, prompting CDC to develop response tools to detect, treat, and prevent infections. Beginning in 2006, CDC and partners created multidisciplinary training programs to strengthen preparedness, covering clinical management, epidemiology and response, laboratory, and veterinary
Sonja J. Olsen, Ann Moen, Joshua A. Mott
wiley   +1 more source

Intradermal delivery of a fractional dose of influenza H7N9 split vaccine elicits protective immunity in mice and rats

Human Vaccines & Immunotherapeutics, 2018
Vaccination is the most effective method of preventing the spread of the influenza virus. However, the traditional intramuscular (IM) immunization causes fear, pain, and cross infection.
Shanshan Zhou, Tianyu Ren, Hongjing Gu, Cheng Wang, Min Li, Zhongpeng Zhao, Li Xing, Liangyan Zhang, Yi Sun, Penghui Yang, Xiliang Wang   +10 more
doaj   +1 more source