Results 61 to 70 of about 13,429 (224)
A novel avian-origin H7N9 influenza A virus (IAV) emerged in China in 2013, causing mild to lethal human respiratory infections. H7N9 originated with multiple reassortment events between avian viruses and carries genetic markers of human adaptation ...
Laurence Josset +4 more
doaj +1 more source
Solving the mystery of H7N9 by crystal balls [PDF]
How the novel influenza H7N9 virus crossed species barrier from avian to human is intriguing. Extrapolation from previous studies on H5N1 can be misleading as illustrated by crystallographic studies on the H7 hemagglutinin with G226L substitution; crystal structure of the neuraminidase N9 showed that R294K substitution interferes with binding to sialic
openaire +2 more sources
Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley +1 more source
Surveillance and response systems for elimination of tropical diseases : summary of a thematic series in infectious diseases of poverty [PDF]
The peer-reviewed journal Infectious Diseases of Poverty provides a new platform to engage with, and disseminate in an open-access format, science outside traditional disciplinary boundaries.
Zhou, Xiao-Nong +17 more
core +1 more source
Characterising routes of H5N1 and H7N9 spread in China using Bayesian phylogeographical analysis [PDF]
Avian influenza H5N1 subtype has caused a global public health concern due to its high pathogenicity in poultry and high case fatality rates in humans.
Dillon C. Adam (6535220) +14 more
core +3 more sources
Broad neutralizing activity of a human monoclonal antibody against H7N9 strains from 2013 to 2017
H7N9 influenza virus has been circulating among humans for five epidemic waves since it was first isolated in 2013 in China. The recent increase in H7N9 infections during the fifth outbreak in China has caused concerns of a possible pandemic.
Cong Chen +5 more
doaj +1 more source
ABSTRACT Public health emergencies (PHEs), as highlighted by the COVID‐19 pandemic, pose major challenges for health management and governments. They jeopardize risk management, require rapid responses in complex scenarios, and determine the allocation of resources and access to vital products and services.
Alex Santos Príncipe +3 more
wiley +1 more source
The outcome of infection with influenza A virus is determined by a complex virus-host interaction. A new H7N9 virus of avian origin crossed the species barrier to infect humans, causing high mortality and emerged as a potential pandemic threat.
Cuisong Zhu +12 more
doaj +1 more source
ABSTRACT Aims H10 subtype avian influenza viruses circulate widely among wild and domestic birds worldwide. These viruses have crossed species barriers to infect mammals, including humans, with cases of H10N3, H10N5 and H10N8 reported. During active surveillance in Guangdong Province, China, between 2023 and 2025, we isolated 10 H10Nx influenza A ...
Jie Liu +7 more
wiley +1 more source
Additional file 1: Figure S1. Phylogenetic tree of the HA gene of avian influenza A(H7N9) viruses in the 5th epidemic wave. A total of 735 H7N9 viruses collected from October 1, 2016 through September 30, 2017 were analyzed.
Xuehua Zhou (5844137) +8 more
core +1 more source

