Results 111 to 120 of about 535,803 (298)
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Advanced Functional Materials, EarlyView.Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Predictions for Future Human Influenza Pandemics [PDF]
The Journal of Infectious Diseases, 1997 Will there be another human influenza pandemic? The certainty is that there will be, and the probability is that the virus will emerge from Eurasian aquatic bird reservoirs and involve reassortment between a human and avian strain, with accumulation of mutations or true recombinational events (or both) that will permit spread and pathogenicity among ...
openaire +2 more sources
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions
Advanced Functional Materials, EarlyView.An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park +10 more
wiley +1 more source
Chicken Supreme: How the Indonesian Poultry Sector Can Survive Avian Influenza [PDF]
Avian influenza is a deadly disease that can spread rapidly through poultry. There are many documented cases of transmission from birds to people, but as yet only rare instances of human to human transmission.
Vanzetti, David
core +1 more source
An influenza pandemic : what it could mean for Scottish tourism [PDF]
, 2006 There is a growing unease among World Health Organisation (WHO) officials and other global disease surveillance organisations that Avian Flu will mutate into a human influenza pandemic.
Connell, Joanne +4 more
core
Advanced Functional Materials, EarlyView.A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu +8 more
wiley +1 more source
Hospital capacity and management preparedness for pandemic influenza in Victoria
Australian and New Zealand Journal of Public Health, 2014 Objective: This study was designed to investigate acute hospital pandemic influenza preparedness in Victoria, Australia, particularly focussing on planning and management efforts.
Ben Dewar, Ian Barr, Priscilla Robinson
doaj +1 more source
Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction
Advanced Functional Materials, EarlyView.This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko +10 more
wiley +1 more source