A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution. [PDF]
Liang W +8 more
europepmc +1 more source
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
Phylogeography and reassortment patterns of human influenza A viruses in sub-Saharan Africa. [PDF]
Owuor DC +8 more
europepmc +2 more sources
Chronology of H3N2 human influenza virus surface glycoprotein adaptation from 1968 to 2019 reveals a surge of adaptation between 1997 and 2002. [PDF]
Lei H +9 more
europepmc +1 more source
Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx. [PDF]
Vangeti S +12 more
europepmc +1 more source
A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan +3 more
wiley +1 more source
Mapping the Global Antigenic Evolution of Human Influenza A/H3N2 Neuraminidase Based on a Machine Learning Model - 1968-2024. [PDF]
Feng J +7 more
europepmc +1 more source
Assessing the fitness of a dual-antiviral drug resistant human influenza virus in the ferret model. [PDF]
Stannard HL +11 more
europepmc +1 more source
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi +7 more
wiley +1 more source

