Results 251 to 260 of about 535,803 (298)

Avian–human influenza epidemic model

Mathematical Biosciences, 2007
A mathematical model is proposed to interpret the spread of avian influenza from the bird world to the human world. Our mathematical model warns that two types of the outbreak of avian influenza may occur if the humans do not prevent the spread of avian influenza. Moreover, it suggests that we cannot feel relieved although the total infected humans are
Iwami, Shingo, Takeuchi, Yasuhiro, Liu, Xianning   +2 more
openaire   +3 more sources

Haemophilus influenzae - human specific bacteria

Frontiers in Bioscience, 2001
Haemophilus influenzae is both a commensal and a pathogen specific to humans. Here we review this bacterium with special emphasis on characteristics that may be involved in virulence.
C F, Marrs, G P, Krasan, K W, McCrea, D L, Clemans, J R, Gilsdorf   +4 more
openaire   +2 more sources

Avian influenza and human health

Acta Tropica, 2002
Natural infections with influenza A viruses have been reported in a variety of animal species including humans, pigs, horses, sea mammals, mustelids and birds. Occasionally devastating pandemics occur in humans. Although viruses of relatively few HA and NA subtype combinations have been isolated from mammalian species, all 15 HA subtypes and all 9 NA ...
Ilaria, Capua, Dennis J, Alexander
openaire   +2 more sources

Avian influenza viruses infecting humans

Cellular and Molecular Life Sciences CMLS, 2000
Avian species, particularly waterfowl, are the natural hosts of influenza A viruses. Influenza viruses bearing each of the 15 hemagglutinin and nine neuraminidase subtypes infect birds and serve as a reservoir from which influenza viruses or genes are introduced into the human population.
K, Subbarao, J, Katz
openaire   +2 more sources

Avian Flu to Human Influenza

Annual Review of Medicine, 2006
Influenza A viral infection causes substantial annual morbidity and mortality worldwide, particularly for infants, the elderly, and the immunocompromised. The virus mainly replicates in the respiratory tract and is spread by respiratory secretions. A growing concern is the recent identification of H5N1 strains of avian influenza A in Asia that were ...
openaire   +2 more sources

Experimental human influenza: observations from studies of influenza antivirals

Antiviral Therapy, 2012
Randomized, placebo-controlled trials have been conducted for nearly five decades in experimentally induced human influenza infections to assess the effectiveness, tolerability and pharmacological properties of influenza antivirals. The results of such studies have not only provided key proof-of-concept data to facilitate drug development but also ...
openaire   +2 more sources

Recent changes among human influenza viruses

Virus Research, 2004
Recurrent epidemics of influenza are due to the frequent emergence of antigenic variants. With co-circulation of two influenza A subtypes and two antigenically distinct lineages of B viruses, genetic reassortment also has an important role in antigenic drift, as illustrated by recent changes in both A and B viruses.
Y P, Lin, V, Gregory, M, Bennett, A, Hay
openaire   +2 more sources

A “universal” human influenza A vaccine

Virus Research, 2004
We have previously reported on a universal human influenza A vaccine, based on the external domain of the transmembrane viral M2-protein (M2e) [Nature Medicine 5 (1999) 1119]. M2-protein is scarcely present on the virus but is abundantly expressed on virus-infected cells.
W, Fiers, M, De Filette, A, Birkett, S, Neirynck, W, Min Jou   +4 more
openaire   +2 more sources

Human Influenza Virus Infections

2014
Influenza virus is a member of the family Orthomyxoviridae. There are five genera within this family of viruses, including Influenzavirus A, Influenzavirus B, Influenzavirus C, Thogotovirus, and Isavirus. Influenza is an enveloped, negative sense ribonucleic acid virus with a segmented genome that replicates in the nucleus of infected cells.
Judith M. Fontana, Daniel P. Eiras, Mirella Salvatore   +2 more
openaire   +1 more source