Results 51 to 60 of about 289,601 (262)

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Handedness and the control of human technology and language

open access: yesHumanities & Social Sciences Communications
The impact of handedness on neural substrates of common tool processing and tool use skills as proxies to the mechanisms underlying modern reciprocal relationships among humans and their brains, the tools they create and use, and technologies they ...
Gregory Kroliczak, Lukasz Przybylski
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Building capacities in human language technology for African languages [PDF]

open access: yesProceedings of the First Workshop on Language Technologies for African Languages - AfLaT '09, 2009
The development of Human Language Technology (HLT) is one of the important by-products of the information revolution. However, the level of knowledge and skills in HLT for African languages remain unfortunately low as most scholars continue to work within the frameworks of knowledge production for an industrial society while the information age dawns ...
openaire   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Human Language Technology and Communicative Disabilities: Requirements and Possibilities for the Future

open access: yesProceedings of the Language Resources and Evaluation Conference, 2010
7th International Conference on Language Resources and Evaluation (LREC), 17 mei ...
Ruiter, M.B.   +4 more
openaire   +4 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Integrating language model embeddings into the ACT-R cognitive modeling framework

open access: yesFrontiers in Language Sciences
In 2025, psycholinguistic research has the benefit of large, high-quality datasets of human behavior, and massively-scalable metrics for variables of interest like frequency and association.
Maryam Meghdadi   +4 more
doaj   +1 more source

Overview of the ARPA human language technology workshop [PDF]

open access: yesProceedings of the workshop on Human Language Technology - HLT '93, 1993
For five years, 1988-1992, the Defense Advanced Projects Agency sponsored a series of meetings called the DARPA Speech and Natural Language Workshops. These workshops provided a forum where researchers in speech and natural language, particularly as relating to the DARPA programs in spoken and written language understanding, could exchange information ...
openaire   +2 more sources

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