Results 61 to 70 of about 18,339,805 (273)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Building capacities in human language technology for African languages [PDF]

Proceedings of the First Workshop on Language Technologies for African Languages - AfLaT '09, 2009
The development of Human Language Technology (HLT) is one of the important by-products of the information revolution. However, the level of knowledge and skills in HLT for African languages remain unfortunately low as most scholars continue to work within the frameworks of knowledge production for an industrial society while the information age dawns ...
openaire   +1 more source

Human Language Technology Audit 2017/18

, 2018
This document reports on all work conducted in the 2017/18 Audit of human language technology (HLT) resources available in South Africa project. The purpose of conducting the HLT Audit 2017/18 is to update the previous HLT Audit conducted by Sharma ...
Moors, Carmen, Gumede, Tebogo, Wilken, Ilana, Calteaux, Karen   +3 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Integrating language model embeddings into the ACT-R cognitive modeling framework

Frontiers in Language Sciences
In 2025, psycholinguistic research has the benefit of large, high-quality datasets of human behavior, and massively-scalable metrics for variables of interest like frequency and association.
Maryam Meghdadi, Maryam Meghdadi, John Duff, Vera Demberg, Vera Demberg   +4 more
doaj   +1 more source

Query Rewriting in Retrieval-Augmented Generation as an Application of NLP Technology for Understanding and Transforming Human Language [PDF]

ITM Web of Conferences
In the context of the rapid development of large-scale model technology, natural language technology has become a bridge connecting humans and computers, which determines the naturalness and accuracy of human-computer interaction.
Qi Haozhe
doaj   +1 more source

Overview of the ARPA human language technology workshop [PDF]

Proceedings of the workshop on Human Language Technology - HLT '93, 1993
For five years, 1988-1992, the Defense Advanced Projects Agency sponsored a series of meetings called the DARPA Speech and Natural Language Workshops. These workshops provided a forum where researchers in speech and natural language, particularly as relating to the DARPA programs in spoken and written language understanding, could exchange information ...
openaire   +2 more sources

Human Language Technology and Communicative Disabilities: Requirements and Possibilities for the Future

Proceedings of the Language Resources and Evaluation Conference, 2010
7th International Conference on Language Resources and Evaluation (LREC), 17 mei ...
Ruiter, M.B., Rietveld, T., Cucchiarini, C., Krahmer, E.J., Strik, H.   +4 more
openaire   +4 more sources

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source