Results 171 to 180 of about 407,045 (310)

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Immune-Related Adverse Events of Checkpoint Inhibitors and Human Leukocyte Antigen System: A Review. [PDF]

Immunotargets Ther
Kośmider K, Kozakiewicz A, Krawczyk P, Kieszko R, Szklener K, Skórzewska M, Wojas-Krawczyk K, Kalinka E, Milanowski J.   +8 more
europepmc   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease. [PDF]

Ann Neurol
Gavrielatos M, Heckman MG, Soto-Beasley AI, Blumenfeld SG, Hou X, Koga S, Murray ME, Kasanuki K, Ono D, Fiesel FC, Uitti RJ, Fields JA, Botha H, Ramanan VK, Kantarci K, Lowe VJ, Jack CR, Ertekin-Taner N, Gibbs JR, Traynor BJ, Dalgard CL, Savica R, Graff-Radford J, Petersen RC, Reichard RR, Graff-Radford NR, Ferman TJ, Boeve BF, Wszolek ZK, Springer W, Gan-Or Z, Mignot E, Scholz SW, Dickson DW, Ross OA.   +34 more
europepmc   +1 more source

Immature dendritic cells induce hyporesponsiveness to alloantigens in vitro and prolong mouse cardiac allograft survival [PDF]

, 1995
Fu, F, Fung, JJ, Lu, L, Qian, S, Starzl, TE, Thomson, AW   +5 more
core  

Studies on transplantation [PDF]

, 1967
Iwasaki, Y, Kashiwagi, N, Marchioro, TL, Starzl, TE   +3 more
core   +1 more source

Human Leukocyte Antigen Sensitization [PDF]

, 2020
openaire   +1 more source

Prediction of KIR3DL1 and human leukocyte antigen binding. [PDF]

J Biol Chem
Maiers M, Louzoun Y, Pymm P, Vivian JP, Rossjohn J, Brooks AG, Saunders PM.   +6 more
europepmc   +1 more source

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

In Silico-Identified Peptides of Five <i>Borrelia burgdorferi</i> Proteins Binding with High Affinity to Human Leukocyte Antigen (HLA) Class II Alleles. [PDF]

Biology (Basel)
Georgopoulos AP, James LM, Sanders M.
europepmc   +1 more source