Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
wiley +1 more source
The role of human leukocyte antigen in HTLV-1 infection and progression to ATLL and HAM/TSP: a systematic review and meta-analysis. [PDF]
Mardi S+4 more
europepmc +1 more source
X‐ray controlled release strategy in cancer therapy
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan+5 more
wiley +1 more source
Genetic testing and human leukocyte antigen in patients with hypertrophic cardiomyopathy and connective tissue diseases. [PDF]
Hiraya D+4 more
europepmc +1 more source
Combating cancer immunotherapy resistance: a nano‐medicine perspective
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong+10 more
wiley +1 more source
Association of Human Leukocyte Antigen Alleles with COVID-19 Severity and Mortality in a Spanish Population. [PDF]
Lobato-Martinez E+8 more
europepmc +1 more source
Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai+6 more
wiley +1 more source
Human leukocyte antigen compatibility and incidence of donor-specific antibodies in pediatric liver transplant recipients. [PDF]
Melere MU+10 more
europepmc +1 more source
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
wiley +1 more source