Results 61 to 70 of about 359,068 (363)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

A Fully Unsupervised Instance Segmentation Technique for White Blood Cell Images [PDF]

open access: yesarXiv, 2023
White blood cells, also known as leukocytes are group of heterogeneously nucleated cells which act as salient immune system cells. These are originated in the bone marrow and are found in blood, plasma, and lymph tissues. Leukocytes kill the bacteria, virus and other kind of pathogens which invade human body through phagocytosis that in turn results ...
arxiv  

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors

open access: yesEinstein (São Paulo)
Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Valeria de Freitas Dutra   +6 more
doaj   +1 more source

Determination of an unrelated donor pool size for human leukocyte antigen-matched platelets in Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2016
Background: Successful transfusion of platelet refractory patients is a challenge. Many potential donors are needed to sustain human leukocyte antigen matched-platelet transfusion programs because of the different types of antigens and the constant needs
Carolina Bonet Bub   +4 more
doaj   +1 more source

Association between human leukocyte antigen and COVID-19 severity

open access: yesActa Medica Iranica, 2021
In the last days of 2019, a new coronavirus emerged in Wuhan, China, and less than 3 months its disease now called COVID-19 was announced a global pandemic by WHO.
Reza Hajebi   +7 more
doaj   +1 more source

Towards Interpretable Classification of Leukocytes based on Deep Learning [PDF]

open access: yesarXiv, 2023
Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify cells with high accuracy where the human observer has little chance to discriminate cells.
arxiv  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

HLA polymorphism in Malay sub-ethnic groups in peninsular Malaysia[R5-130.5]. [PDF]

open access: yes, 2009
Di dalam kajian ini, Human Leukocyte Antigen (HLA) kelas I dan II telah dianalisa dengan menggunakan kaedah pencetus penjujukan khusus (Sequence Specific Primer) di kalangan 176 individu yang tiada pertalian kekeluargaan dari 6 kumpulan sub-etnik Melayu ...
Atan, Edinur Hisham
core  

Human leukocyte antigen - HLA B*27: Unraveling the link to pathogenesis

open access: yesIndian Journal of Rheumatology, 2020
The association of spondyloarthritis (SpA) with human leukocyte antigen-B*27 (HLA-B*27) is one of the strongest known for a non-monogenic disease.
Sakir Ahmed, Ramnath Misra
doaj   +1 more source

Enhancing kidney transplantation through multi-agent kidney exchange programs: A comprehensive review and optimization models [PDF]

open access: yesInternational Journal of Industrial Engineering Computations, 16(2). Growing Science (2024)
This paper presents a comprehensive review of the last two decades of research on Kidney Exchange Programs (KEPs), systematically categorizing and classifying key contributions to provide readers with a structured understanding of advancements in the field.
arxiv   +1 more source

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