Results 101 to 110 of about 22,575,443 (355)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
SÓCRATES, ENTRE MITO Y RAZÓN SOCRATES, BETWEEN MYTH AND REASON
Byzantion Nea Hellás, 2012 En la discusión socrática siempre han de quedar abismos históricos que aluden al personaje mismo y a la figura concreta de un ateniense. Sin embargo, la enseñanza o la práxis derivada de esa disciplina conforman un legado que la filosofía no puede dejar ...
R0BERTO QUIROZ PlZARRO
doaj
Cultural and educational background of formation of sustainable lifestyle [PDF]
, 2013 In the XXI century mankind has approached the global transformation of society, which resulted in creation of a qualitatively new socioeconomic system, which is the knowledge society and the informational society, the foundation of which is the "economy ...
Jubran, J., Syukhina, A.G.
core
A Theological Challenge: Coordinating Biological, Social, and Religious Visions of Humanity [PDF]
, 1998 This paper attempts two tasks. First, it sketches how the natural sciences (including especially the biological sciences), the social sciences, and the scientific study of religion can be understood to furnish complementary, consonant perspectives on ...
Wildman, Wesley J.
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
From Biosemiotics to Semiotics [PDF]
, 2002 Biosemiotics and Semiotics have similarities and differences. Both deal with signal and meaning. One difference is that Biosemiotics covers a domain (life) that is less complex that the one addressed by Semiotics (human).
Menant, Christophe
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Meaning, moral realism, and the importance of morality [PDF]
, 2020 Many philosophers have suspected that the normative importance of morality depends on moral realism. In this paper, I defend a version of this suspicion: I argue that if teleological forms of moral realism, those that posit an objective purpose to human ...
Zhao, Michael
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