Results 51 to 60 of about 32,920 (145)
Shotgun metagenomics to investigate unknown viral etiologies of pediatric meningoencephalitis.
IntroductionMeningoencephalitis in children poses a diagnostic challenge, as etiology remains unknown for most of patients. Viral metagenomics by shotgun sequencing represents a powerful tool for investigating unknown viral infections related to these ...
Andrea Castellot +3 more
doaj +1 more source
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun +10 more
wiley +1 more source
ABSTRACT Background Human adenoviruses (HAdV) circulate globally, but their seasonal patterns remain poorly defined. We aimed to characterize the timing, amplitude, and duration of HAdV epidemics worldwide and to compare patterns before and after the COVID‐19 pandemic.
Emma Papini +13 more
wiley +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut +1 more
wiley +1 more source
ABSTRACT Background Nucleic acid amplification tests (NAATs) for human adenoviruses (HAdVs) causing respiratory infections usually target the hexon gene. However, new HAdV types with substantial variations in the hexon gene may not be detected. Thus, we focus on NAATs based on a conserved region in the penton gene to detect all HAdV types causing ...
Benedikt Beilstein +4 more
wiley +1 more source
ABSTRACT Background Adenovirus (AdV) is a non‐enveloped virus with a double‐stranded DNA genome that can infect the respiratory and gastrointestinal tracts, as well as cause conjunctivitis. The infection is influenced by the patient's age, environment, temperature, and immunocompromised individuals.
Taslima Jamal Urmi +2 more
wiley +1 more source
Respiratory Co-Infections: Modulators of SARS-CoV-2 Patients’ Clinical Sub-Phenotype
Co-infection with ancillary pathogens is a significant modulator of morbidity and mortality in infectious diseases. There have been limited reports of co-infections accompanying SARS-CoV-2 infections, albeit lacking India specific study.
Priyanka Mehta +34 more
doaj +1 more source
ABSTRACT Human adenoviruses of species B (HAdV‐B) can cause upper respiratory tract infections and conjunctivitis, but also severe lower respiratory tract infections (LRTI). Although HAdV‐associated LRTI are non‐notifiable in Germany, typing data of our Adenovirus Reference Laboratory indicated an HAdV‐B3 epidemic in 2023, with 67 samples initially ...
Tina Ganzenmueller +5 more
wiley +1 more source
Wild felids are vital to maintaining the ecological balance in natural environments as they regulate prey populations at different levels of the food chain.
Ygor Machado +5 more
doaj +1 more source

