Results 81 to 90 of about 32,920 (145)

Human Mastadenovirus A Infection in a Child During the Course of Hematopoietic Stem Cell Transplant.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
Following primary infection, human mastadenoviruses can persist in various tissues. We report a case of a pediatric patient with Fanconi anemia who had a complicated posttransplant course after allogeneic hematopoietic stem cell transplant that was associated with human mastadenovirus infection.
Siddika Songul, Yalcin, B Baris, Kuskonmaz, Vicente, Perez-Brocal, Duygu, Uckan Cetinkaya, Andres, Moya, Ener Cagri, Dinleyici   +5 more
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Bioinformatics-based screening tool identifies a wide variety of human and zoonotic viruses in Trujillo-Peru wastewater

One Health
Peru was one of the most affected countries during the COVID-19 pandemic. Moreover, multiple other viral diseases (enteric, respiratory, bloodborne, and vector-borne) are endemic and rising.
Brijen Miyani, Yabing Li, Heidy Peidro Guzman, Ruben Kenny Briceno, Sabrina Vieyra, Rene Hinojosa, Irene Xagoraraki   +6 more
doaj   +1 more source

Meta-transcriptomics characterization of individual Marmota sibirica reveals a wide spectrum of viral and bacterial pathogens in Inner Mongolia of China

Microbiology Spectrum
Mongolian marmot is a reservoir for various zoonotic pathogens, including Yersinia pestis, Bartonella, and hantaviruses. However, our understanding of the marmot’s pathogen profile remains incomplete. Here, we used an unbiased metatranscriptomic approach
Min-Wu Peng, Yu-Hui Wu, Zi-Rui Ren, Narigen, Rui-Sen Hou, Gen-Yang Xin, Yu-Qi Liao, Jing Wang, Shi-Jia Le, Pei-Bo Shi, Hai-Long Zhao, Zi-Qing Deng, Da-Xi Wang, Chaolemen, Mang Shi   +14 more
doaj   +1 more source

Investigating an agnostic metagenomic virus discovery tool and evaluating the performance of Ion Torrent versus Oxford Nanopore Technology sequencing

International Journal of Infectious Diseases
Introduction and motivation: Emerging and re-emerging viruses are a global health concern. Historically, such viruses have been identified through targeted approaches, which has been the gold standard in diagnosis.
Ms Tshegofatso Mahlangu, Dr Tongai Maponga, Mr Martin Deijs, Prof Lia van der Hoek, Prof Gert van Zyl, Prof Davey Smith   +5 more
doaj   +1 more source

Clinical application value of simultaneous plasma and bronchoalveolar lavage fluid metagenomic next generation sequencing in patients with pneumonia-derived sepsis

BMC Infectious Diseases
Background Despite the increasing use of metagenomic next-generation sequencing (mNGS) in sepsis, identifying clinically relevant pathogens remains challenging.
Jiayan Li, Dongxu Pan, Yuxin Guo, Bo Zhang, Xinglin Lu, Chen Deng, Feifei Xu, Zongnan Lv, Qinhe Chen, Yafeng Zheng, Shuhao Nong, Lihua Su, Rongfa Qin, Fufu Jiang, Wei Gai, Gang Qin   +15 more
doaj   +1 more source

Enhancing infectious intestinal disease diagnosis through metagenomic and metatranscriptomic sequencing of 1000 human diarrhoeal samples

Genome Medicine
Background Current surveillance of diarrhoeal disease is hindered by limitations of traditional diagnostic approaches, which often fail to identify the causative organism, particularly for novel or hard-to-culture bacterial pathogens.
Edward Cunningham-Oakes, Blanca M. Perez-Sepulveda, Yan Li, Jay C. D. Hinton, Charlotte A. Nelson, K. Marie McIntyre, Maya Wardeh, Sam Haldenby, Richard Gregory, Miren Iturriza-Gómara, Christiane Hertz-Fowler, Sarah J. O’Brien, Nigel A. Cunliffe, Alistair C. Darby, on behalf of the INTEGRATE consortium   +14 more
doaj   +1 more source

A study of the genetic divergence of Human mastadenovirus D via comparative genomic analyses

A study of the genetic divergence of Human mastadenovirus D via comparative genomic analyses
Human mastadenovirus D (HAdV-D) is an exceptionally type-rich human adenovirus species and causative agent of different diseases and neonatal fatalities, as well as an opportunistic pathogen in immune-compromised patients. A research group, including the author of this thesis, revealed that intertypic homologous recombination events between distant ...
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Interregional Coevolution Analysis Revealing Functional and Structural Interrelatedness between Different Genomic Regions in Human Mastadenovirus D

Interregional Coevolution Analysis Revealing Functional and Structural Interrelatedness between Different Genomic Regions in Human Mastadenovirus D
Human mastadenovirus D (HAdV-D) is exceptionally rich in type among the seven human adenovirus species. This feature is attributed to frequent intertypic recombination events that have reshuffled orthologous genomic regions between different HAdV-D types. However, this trend appears to be paradoxical, as it has been demonstrated that the replacement of
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A Case of Type 54 Human Mastadenovirus Keratoconjunctivitis Causing Severe Broad Epithelial Defect Ten Years after LASIK Surgery

Japanese Journal of Infectious Diseases, 2017
Shuji, Suzuki, Tomoko, Kawamura, Yusuke, Saeki, Mika, Okubo, Masami, Konagaya, Nozomu, Hanaoka, Takeshi, Arashiro, Tsuguto, Fujimoto, Eiichi, Uchio   +8 more
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First isolation of a new type of human adenovirus (genotype 79), species Human mastadenovirus B (B2) from sewage water in Japan

First isolation of a new type of human adenovirus (genotype 79), species Human mastadenovirus B (B2) from sewage water in Japan
Human mastadenoviruses (HAdVs) are highly infectious viral pathogens that survive for prolonged periods in environmental waters. We monitored the presence of HAdVs in sewage waters between April 2014 and March 2015. A total of 27 adenoviral strains were detected in 75% (18/24 in occasion-base) of 24 wastewater collected samples. We identified the types
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