Results 251 to 260 of about 2,261,504 (355)

Intestinal microbial metabolites in human metabolism and type 2 diabetes. [PDF]

Diabetologia, 2020
Herrema H, Niess JH, Niess JH.
europepmc   +1 more source

Study of anabolic agents metabolism using in vitro system of human hepatocyte cell line

, 2016
I. Huliuta, A. Shynhel
openalex   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

How Wastewater Reflects Human Metabolism─Suspect Screening of Pharmaceutical Metabolites in Wastewater Influent. [PDF]

Environ Sci Technol
Meyer C, Stravs MA, Hollender J.
europepmc   +1 more source

The Design and Validation of a Discrete-Event Simulator for Carbohydrate Metabolism in Humans

, 2020
Husam Ghazaleh
openalex   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

In Vitro and In Vivo Human Metabolism of Ostarine, a Selective Androgen Receptor Modulator and Doping Agent. [PDF]

Int J Mol Sci
Taoussi O, Bambagiotti G, Gameli PS, Daziani G, Tavoletta F, Tini A, Basile G, Lo Faro AF, Carlier J.   +8 more
europepmc   +1 more source

Effects of calcium antagonists on low density lipoprotein metabolism in human arterial smooth muscle cells.

, 1988
Seijiro Mori, Hideki Ito, Kazuhiro Yamamoto   +2 more
openalex   +2 more sources

HUMAN COMPLEMENT METABOLISM

Medicine, 1975
S. RUDDY, C. B. CARPENTER, K. W. CHIN, J. N. KNOSTMAN, N. A. SOTER, O. GOTZE, H. J. MULLER-EBERHARD, K. F. AUSTEN   +7 more
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source