Results 111 to 120 of about 9,306,580 (247)

Diversity of Rhinovirus and Enterovirus Infections Among Pediatric Patients Hospitalized in Wisconsin, 2022–2023

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Severe rhinovirus (RV)/enterovirus (EV) respiratory infections in pediatric patients increased in the US during 2022–2023. This study aimed to characterize RV/EV genetic diversity among hospitalized children in Wisconsin and describe demographic and clinical factors of patients by RV/EV type.
Hannah L. Litwak, Carlos M. Perez, Allen Bateman, Kyley Anhalt, Xiaoyan Lu, Shannon Rogers, Brian Emery, Terry Fei Fan Ng, Caelin Cubenas, Cria O. Gregory, Clinton Paden, Thomas Haupt, Hannah L. Kirking, Hannah E. Segaloff   +13 more
wiley   +1 more source

Interferon-Mediated Response to Human Metapneumovirus Infection

Viruses, 2018
Human metapneumovirus (HMPV) is one of the leading causes of respiratory diseases in infants and children worldwide. Although this pathogen infects mainly young children, elderly and immunocompromised people can be also seriously affected. To date, there
Ifeanyi K. Uche, Antonieta Guerrero-Plata   +1 more
doaj   +1 more source

Diagnostic and Clinical Value of Targeted Next‐Generation Sequencing for Pediatric Respiratory Infections in Northern China

The Clinical Respiratory Journal, Volume 20, Issue 4, April 2026.
A total of 1209 patients with suspected respiratory tract infections (RTIs) who underwent targeted next‐generation sequencing (tNGS) were screened at Qingdao Huangdao District People's Hospital, Qingdao, China, from April 1, 2023, to December 31, 2023. Of these, 940 patients were enrolled in the study.
Lixiang Wang, Xue Yang, Lexia Yang, Ke Yin, Hui Zhong   +4 more
wiley   +1 more source

Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management. [PDF]

, 2019
Community-acquired pneumonia (CAP) is a common cause of pediatric hospital admission. Empiric antibiotic therapy for hospitalized children with serious CAP now targets the most likely pathogen(s), including those that may demonstrate significant ...
Bradley, John S, Cannavino, Christopher R, Coufal, Nicole G, Farnaes, Lauge, Foley, Jennifer, Hong, David K, Pong, Alice, Ryan Loker, Kathleen, Wilke, Julianne   +8 more
core  

Respiratory Viral Infections and the Tonsillar Transcriptome: An Exploratory Study

Clinical &Experimental Allergy, EarlyView.
Tanzeela Hanif, Lotta E. Ivaska, Antti Silvoniemi, Emilia Mikola, Tuomo Puhakka, Oscar Palomares, Sanna Toppila‐Salmi, Mubeccel Akdis, Cezmi A. Akdis, Tuomas Jartti   +9 more
wiley   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, Volume 13, Issue 17, 23 March 2026.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Human Metapneumovirus: Etiological Agent of Severe Acute Respiratory Infections in Hospitalized and Deceased Patients with a Negative Diagnosis of Influenza

Pathogens, 2020
Human metapneumovirus (HMPV) is one of the four major viral pathogens associated with acute respiratory tract infections (ARI) and creates a substantial burden of disease, particularly in young children (<5 years) and older individuals (≥65 ...
Gisela Barrera-Badillo, Beatriz Olivares-Flores, Adriana Ruiz-López, Miguel Ángel Fierro-Valdez, Rosaura Idania Gutiérrez-Vargas, Irma López-Martínez   +5 more
doaj   +1 more source

Molecular assays for detection of human metapneumovirus [PDF]

, 2003
The recent description of the respiratory pathogen human metapneumovirus (hMPV) has highlighted a deficiency in current diagnostic techniques for viral agents associated with acute lower respiratory tract infections.
Mackay, Ian M., Jacob, Kevin C., Woolhouse, Daniel, Waller, Katharine, Syrmis, Melanie W., Whiley, David M., Siebert, David J., Nissen, Michael, Sloots, Theo P.   +8 more
core   +2 more sources

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

Dendritic Cells in Human Pneumovirus and Metapneumovirus Infections

Viruses, 2013
Lung dendritic cells (DC) play a fundamental role in sensing invading pathogens, as well as in the control of tolerogenic responses in the respiratory tract.
Antonieta Guerrero-Plata
doaj   +1 more source