Results 1 to 10 of about 691 (84)

Recent Molecular Evolution of Human Metapneumovirus (HMPV): Subdivision of HMPV A2b Strains

Microorganisms, 2020
Human metapneumovirus (HMPV) is a major etiological agent of acute respiratory infections in humans. HMPV has been circulating worldwide for more than six decades and is currently divided into five agreed-upon subtypes: A1, A2a, A2b, B1, and B2. Recently,
Tsuyoshi Sekizuka, Ko Sato, Hidekazu Nishimura   +2 more
exaly   +3 more sources

HMPV in Immunocompromised Patients: Frequency and Severity in Pediatric Oncology Patients

Pathogens, 2020
Cancer is the first cause of death by disease in childhood globally. The most frequent types of cancers in children and adolescents are leukemias, followed by brain and central nervous system tumors and lymphomas.
Cesar Martinez-Rodriguez, Ma. del Rocio Banos-Lara   +1 more
exaly   +3 more sources

Non-Coding RNAs and Their Role in Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV) Infections

Viruses, 2020
Recent high-throughput sequencing revealed that only 2% of the transcribed human genome codes for proteins, while the majority of transcriptional products are non-coding RNAs (ncRNAs).
Yong Sun Lee, Xiaoyong Bao, Inhan Lee
exaly   +3 more sources

Clinical comparison of HMPV and RSV infections in hospitalised Malaysian children: A propensity score matched study

Clinical Respiratory Journal
Introduction Human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) are significant contributors to the burden of acute respiratory infections in children, but data on hMPV from Southeast Asia are limited despite its potential for serious ...
David Ce Ng, Erwin J Khoo, Kah Kee Tan
exaly   +2 more sources

Probenecid Inhibits Human Metapneumovirus (HMPV) Replication In Vitro and in BALB/c Mice

Viruses
Human metapneumovirus (HMPV) is an important cause of acute respiratory tract infection and causes significant morbidity and mortality. There is no specific antiviral drug to treat HMPV or vaccine to prevent HMPV.
Harrison C Bergeron, Ralph A Tripp, Tamás Nagy   +2 more
exaly   +3 more sources

A chimeric influenza virus vaccine expressing fusion protein epitopes induces protection from human metapneumovirus challenge in mice

Frontiers in Microbiology, 2023
Human metapneumovirus (HMPV) is a common virus associated with acute respiratory distress syndrome in pediatric patients. There are no HMPV vaccines or therapeutics that have been approved for prevention or treatment.
Tian Chongyu, Tian Chongyu, Lei Guanglin, Sun Fang, Deng Zhuoya, Yang Hao, Li Cong, Li Xinyu, He Wei, Tan Lingyun, Niu Yan, Yang Penghui, Yang Penghui, Yang Penghui   +13 more
doaj   +1 more source

Epidemiology, genetic characteristics, and association with meteorological factors of human metapneumovirus infection in children in southern China: A 10-year retrospective study

International Journal of Infectious Diseases, 2023
Objectives: This study aimed to determine the epidemiological and genetic features of human metapneumovirus (HMPV) infection in children in southern China, and the effect of meteorological factors on infection.
Hengming Ye, Shuqing Zhang, Kexin Zhang, Yizhe Li, Delin Chen, Yongyao Tan, Linyue Liang, Minjie Liu, Jingyao Liang, Shu An, Jueheng Wu, Xun Zhu, Mengfeng Li, Zhenjian He   +13 more
doaj   +1 more source

Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes. [PDF]

PLoS Pathogens, 2015
Human metapneumovirus (HMPV), a member of the Paramyxoviridae family, is a leading cause of lower respiratory illness. Although receptor binding is thought to initiate fusion at the plasma membrane for paramyxoviruses, the entry mechanism for HMPV is ...
Reagan G Cox, Bernardo A Mainou, Monika Johnson, Andrew K Hastings, Jennifer E Schuster, Terence S Dermody, John V Williams   +6 more
doaj   +1 more source

Epidemiology and genotypic diversity of human metapneumovirus in paediatric patients with acute respiratory infection in Beijing, China

Virology Journal, 2021
Background Acute respiratory tract infections (ARTIs) causes high amounts of morbidity and mortality worldwide every year. Human metapneumovirus (HMPV) is a major pathogen of ARTIs in children.
Chao Wang, Tianli Wei, Fenlian Ma, Hao Wang, Jianqiang Guo, Aijun Chen, Yiman Huang, Zhiping Xie, Lishu Zheng   +8 more
doaj   +1 more source

Human metapneumovirus (hMPV): a re-emerging respiratory threat – transmission, clinical features, complications and management [PDF]

Infectious Diseases and Tropical Medicine
Human metapneumovirus (hMPV) is a globally prevalent yet underrecognized respiratory pathogen that disproportionately affects high-risk populations. Between 2024 and January 2025, numerous hMPV clinical cases were recorded in China, India, and other ...
S. Aishath, S. Kannan, F. Razana, A. Sheeza   +3 more
doaj   +1 more source