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Recent Molecular Evolution of Human Metapneumovirus (HMPV): Subdivision of HMPV A2b Strains [PDF]
Microorganisms, 2020 Human metapneumovirus (HMPV) is a major etiological agent of acute respiratory infections in humans. HMPV has been circulating worldwide for more than six decades and is currently divided into five agreed-upon subtypes: A1, A2a, A2b, B1, and B2. Recently,
Tsuyoshi Sekizuka +2 more
exaly +5 more sources
Viruses, 2020 Recent high-throughput sequencing revealed that only 2% of the transcribed human genome codes for proteins, while the majority of transcriptional products are non-coding RNAs (ncRNAs).
Yong Sun Lee, Xiaoyong Bao, Inhan Lee
exaly +3 more sources
Probenecid Inhibits Human Metapneumovirus (HMPV) Replication In Vitro and in BALB/c Mice
VirusesHuman metapneumovirus (HMPV) is an important cause of acute respiratory tract infection and causes significant morbidity and mortality. There is no specific antiviral drug to treat HMPV or vaccine to prevent HMPV.
Harrison C Bergeron +2 more
exaly +3 more sources
Clinical Respiratory JournalIntroduction Human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) are significant contributors to the burden of acute respiratory infections in children, but data on hMPV from Southeast Asia are limited despite its potential for serious ...
David Ce Ng, Erwin J Khoo, Kah Kee Tan
exaly +2 more sources
A Narrative Review of Current Updates, Advancements, and Evolving Landscape in Public Health Research of Human Metapneumovirus [PDF]
Indian Journal of Community MedicineHuman metapneumovirus (hMPV) is among the common sources of acute respiratory infection (ARI) that appears especially during the winter and spring season. The virus remains in circulation around the world and has been reported to contribute 5–25% of ARIs,
Sumit Aggarwal +2 more
doaj +2 more sources
Frontiers in Microbiology, 2023 Human metapneumovirus (HMPV) is a common virus associated with acute respiratory distress syndrome in pediatric patients. There are no HMPV vaccines or therapeutics that have been approved for prevention or treatment.
Tian Chongyu +13 more
doaj +1 more source
HMPV in Immunocompromised Patients: Frequency and Severity in Pediatric Oncology Patients
Pathogens, 2020 Cancer is the first cause of death by disease in childhood globally. The most frequent types of cancers in children and adolescents are leukemias, followed by brain and central nervous system tumors and lymphomas.
Cesar Martinez-Rodriguez +1 more
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International Journal of Infectious Diseases, 2023 Objectives: This study aimed to determine the epidemiological and genetic features of human metapneumovirus (HMPV) infection in children in southern China, and the effect of meteorological factors on infection.
Hengming Ye +13 more
doaj +1 more source
Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes. [PDF]
PLoS Pathogens, 2015 Human metapneumovirus (HMPV), a member of the Paramyxoviridae family, is a leading cause of lower respiratory illness. Although receptor binding is thought to initiate fusion at the plasma membrane for paramyxoviruses, the entry mechanism for HMPV is ...
Reagan G Cox +6 more
doaj +1 more source
The human metapneumovirus matrix protein stimulates the inflammatory immune response in vitro. [PDF]
PLoS ONE, 2011 Each year, during winter months, human Metapneumovirus (hMPV) is associated with epidemics of bronchiolitis resulting in the hospitalization of many infants.
Audrey Bagnaud-Baule +8 more
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