Results 11 to 20 of about 2,894 (131)

Human Metapneumovirus (hMPV) Infection and MPV467 Treatment in Immunocompromised Cotton Rats Sigmodon hispidus

Viruses, 2023
Human metapneumovirus (hMPV) is an important cause of respiratory disease in immunocompromised individuals, yet hMPV infection has not been modeled before in immunocompromised animals. In this work, cotton rats S.
Kevin C. Yim, Jarrod J. Mousa, Jorge C. G. Blanco, Sonnie Kim, Marina S. Boukhvalova   +4 more
doaj   +2 more sources

Serological analysis of HMPV F immunized animals.

, 2023
(A) Anti-HMPV prefusion and postfusion IgG responses of NHP sera were measured by ELISA against HMPV F prefusion or postfusion immunogens. Ratios of prefusion vs postfusion were in right panel. (B) Anti-HMPV prefusion and postfusion responses of NHP sera
Ruth A. Woodward (17027779), Peter D. Kwong, Erik-Stephane D. Stancofski (17027773), Erik-Stephane D. Stancofski, Andrea Biju (17027770), Tongqing Zhou, Tongqing Zhou (263499), Cheng-Yan Zheng (17027776), Ruth A. Woodward, Baoshan Zhang (758831), John R. Mascola, Ursula J. Buchholz (7252559), I-Ting Teng, Baoshan Zhang, Ursula J. Buchholz, Steven J. Chen (17027767), Steven J. Chen, John-Paul Todd, Peter D. Kwong (161423), Cheng Cheng, Wing-Pui Kong (3147984), Lijuan Yang (1538233), Yaroslav Tsybovsky (2176332), Andrea Biju, Nicholas C. Morano (9905516), Nicholas C. Morano, Cheng-Yan Zheng, Cheng Cheng (68821), Shuishu Wang, Li Ou (2090878), Lawrence Shapiro (2794138), Lijuan Yang, Lawrence Shapiro, Shuishu Wang (1348446), Li Ou, I-Ting Teng (734342), John R. Mascola (229761), Wing-Pui Kong, Yaroslav Tsybovsky, John-Paul Todd (6054251)   +39 more
core   +1 more source

Antibody recognition of the Pneumovirus fusion protein trimer interface.

PLoS Pathogens, 2020
Human metapneumovirus (hMPV) is a leading cause of viral respiratory infection in children, and can cause severe lower respiratory tract infection in infants, the elderly, and immunocompromised patients.
Jiachen Huang, Darren Diaz, Jarrod J Mousa   +2 more
doaj   +1 more source

Epidemiology and genotypic diversity of human metapneumovirus in paediatric patients with acute respiratory infection in Beijing, China

Virology Journal, 2021
Background Acute respiratory tract infections (ARTIs) causes high amounts of morbidity and mortality worldwide every year. Human metapneumovirus (HMPV) is a major pathogen of ARTIs in children.
Chao Wang, Tianli Wei, Fenlian Ma, Hao Wang, Jianqiang Guo, Aijun Chen, Yiman Huang, Zhiping Xie, Lishu Zheng   +8 more
doaj   +1 more source

Phylogenetic variability of Human Metapneumovirus in patients with acute respiratory infections in Cameroon, 2011–2014

Journal of Infection and Public Health, 2020
Background: Identified in 2001, Human Metapneumovirus (HMPV) is a Pneumovirus associated with acute lower and upper respiratory infections in all age groups and especially in newborns, elderly and immunocompromised subjects. Data are still limited in sub-
Sebastien Kenmoe, Marie-Astrid Vernet, Véronique Penlap Beng, Astrid Vabret, Richard Njouom   +4 more
doaj   +1 more source

Global Extension and Predominance of Human Metapneumovirus A2 Genotype with Partial G Gene Duplication

Viruses, 2022
Human metapneumovirus (HMPV) is an important respiratory pathogen and is divided in two main groups (A and B). HMPV strains with partial duplications (111-nt and 180-nt duplication) of the G gene have been reported in recent years.
Juan Carlos Muñoz-Escalante, Gabriel Mata-Moreno, Gerardo Rivera-Alfaro, Daniel E. Noyola   +3 more
doaj   +1 more source

Engineered HMPV F glycoprotein variants.

, 2023
The Pneumoviridae family of viruses includes human metapneumovirus (HMPV) and respiratory syncytial virus (RSV). The closely related Paramyxoviridae family includes parainfluenza viruses (PIVs).
Ruth A. Woodward (17027779), Nicholas C. Morano (9905516), Erik-Stephane D. Stancofski (17027773), Cheng Cheng (68821), Li Ou (2090878), Andrea Biju (17027770), Tongqing Zhou (263499), Lawrence Shapiro (2794138), Cheng-Yan Zheng (17027776), Baoshan Zhang (758831), Ursula J. Buchholz (7252559), Shuishu Wang (1348446), Steven J. Chen (17027767), I-Ting Teng (734342), John R. Mascola (229761), Peter D. Kwong (161423), Wing-Pui Kong (3147984), Lijuan Yang (1538233), John-Paul Todd (6054251), Yaroslav Tsybovsky (2176332)   +19 more
core   +1 more source

Comparing Human Metapneumovirus and Respiratory Syncytial Virus: Viral Co-Detections, Genotypes and Risk Factors for Severe Disease.

PLoS ONE, 2017
BackgroundIt is unclarified as to whether viral co-detection and human metapneumovirus (HMPV) genotypes relate to clinical manifestations in children with HMPV and lower respiratory tract infection (LRTI), and if the clinical course and risk factors for ...
Nina Moe, Sidsel Krokstad, Inger Heimdal Stenseng, Andreas Christensen, Lars Høsøien Skanke, Kari Ravndal Risnes, Svein Arne Nordbø, Henrik Døllner   +7 more
doaj   +1 more source

Human Metapneumovirus in Turkey Poults

Emerging Infectious Diseases, 2006
This study was conducted to reexamine the hypothesis that human metapneumovirus (hMPV) will not infect turkeys. Six groups of 2-week-old turkeys (20 per group) were inoculated oculonasally with 1 of the following: noninfected cell suspension; hMPV ...
Binu T. Velayudhan, Kakambi V. Nagaraja, Anil J. Thachil, Daniel P. Shaw, Gregory C. Gray, David A. Halvorson   +5 more
doaj   +1 more source

Host Components That Modulate the Disease Caused by hMPV

, 2021
Human metapneumovirus (hMPV) is one of the main pathogens responsible for acute respiratory infections in children up to 5 years of age, contributing substantially to health burden.
Kalergis, Alexis M., Alexis M. Kalergis, Pacheco, Gaspar A., Gaspar A. Pacheco, Abel E. Vásquez, Gálvez, Nicolás M.S., Rivera, Thomas, Nicolás M. S. Gálvez, Stranger, Vicente, Thomas Rivera, Catalina A. Andrade, Vicente Stranger, Soto, Jorge A., Andrade, Catalina A., Vásquez, Abel E., Jorge A. Soto   +15 more
core   +2 more sources