Results 11 to 20 of about 11,358 (217)

Molecular epidemiology of human metapneumovirus (hMPV) in Cambodia [PDF]

BMC Proceedings, 2011
Background First identified in 2001, human metapneumovirus (hMPV) is a novel pathogen and causative agent of acute respiratory tract infection. Re-infection with hMPV is common, and currently there is no available vaccine against this virus. Two genetic subgroups (A and B) have been identified, both of which can be divided further into at least two ...
Arnott, Alicia, Sek, Mardy, Vong, Sirenda, Buchy, Philippe   +3 more
openaire   +3 more sources

A Narrative Review of Current Updates, Advancements, and Evolving Landscape in Public Health Research of Human Metapneumovirus [PDF]

Indian Journal of Community Medicine
Human metapneumovirus (hMPV) is among the common sources of acute respiratory infection (ARI) that appears especially during the winter and spring season. The virus remains in circulation around the world and has been reported to contribute 5–25% of ARIs,
Sumit Aggarwal, Pragati Agarwal, Ankita Singh Chakotiya   +2 more
doaj   +2 more sources

Deep learning approach for automated hMPV classification

Scientific Reports
Human metapneumovirus (hMPV) is a significant cause of respiratory illness, particularly in children, elderly individuals, and immunocompromised patients. Despite its clinical relevance, hMPV poses diagnostic challenges due to its symptom similarity with
Sivarama Prasad Tera, Ravikumar Chinthaginjala, Irum Shahzadi, Priya Natha, Safia Obaidur Rab   +4 more
doaj   +3 more sources

A chimeric influenza virus vaccine expressing fusion protein epitopes induces protection from human metapneumovirus challenge in mice

Frontiers in Microbiology, 2023
Human metapneumovirus (HMPV) is a common virus associated with acute respiratory distress syndrome in pediatric patients. There are no HMPV vaccines or therapeutics that have been approved for prevention or treatment.
Tian Chongyu, Tian Chongyu, Lei Guanglin, Sun Fang, Deng Zhuoya, Yang Hao, Li Cong, Li Xinyu, He Wei, Tan Lingyun, Niu Yan, Yang Penghui, Yang Penghui, Yang Penghui   +13 more
doaj   +1 more source

hMPV Lineage Nomenclature and Heparin Binding [PDF]

Viruses, 2013
Human metapneumovirus (hMPV), first described in 2001 [1], is responsible for causing serious respiratory illness in young children, the elderly and immunocompromised patients. Four distinct lineages of hMPV have been identified with the original nomenclature for these subgroups (A1, A2, B1 and B2), reported by van den Hoogen et al.
David Gordon, John Williams, Gamaliel Muchondo, Tania Sadlon, Penelope Adamson, Sutthiwan Thammawat   +5 more
openaire   +3 more sources

Respiratory syncytial virus infection induces higher Toll-like receptor-3 expression and TNF-α production than human metapneumovirus infection [PDF]

, 2013
published_or_final_versio
A Guerrero-Plata, A Guerrero-Plata, A Le Bon, AR Falsey, B Olszewska-Pazdrak, BD Rudd, BG Van den Hoogen, BG van den Hoogen, C Marguet, CB Hall, DJ Groskreutz, E Abraham, F Heil, G Boivin, H Hemmi, Hua-wei Mao, JE Gern, JF Valarcher, JM Lund, JS Yoon, JV Williams, KM Spann, L Alexopoulou, L Genestier, L Guillot, LM Haynes, M Karin, MJ Holtzman, ML Von Linstow, MM Monick, MQ Zhao, MR Murawski, N Cimolai, N Sigurs, O Ueba, P Sheeran, Q Sha, Q Sha, R Janssen, Ralph Tripp, RP Garofalo, S Akira, S Akira, S Baron, S Matsukura, S Viazov, SS Diebold, T Kawai, TL Noah, Wen-wei Tu, XH Xie, Xiao-dong Zhao, Yao Zhao, Ying Dou, Zhi-yong Zhang   +54 more
core   +16 more sources

HMPV in Immunocompromised Patients: Frequency and Severity in Pediatric Oncology Patients

Pathogens, 2020
Cancer is the first cause of death by disease in childhood globally. The most frequent types of cancers in children and adolescents are leukemias, followed by brain and central nervous system tumors and lymphomas.
Cesar Martinez-Rodriguez, Ma. del Rocio Banos-Lara   +1 more
doaj   +1 more source

Epidemiology, genetic characteristics, and association with meteorological factors of human metapneumovirus infection in children in southern China: A 10-year retrospective study

International Journal of Infectious Diseases, 2023
Objectives: This study aimed to determine the epidemiological and genetic features of human metapneumovirus (HMPV) infection in children in southern China, and the effect of meteorological factors on infection.
Hengming Ye, Shuqing Zhang, Kexin Zhang, Yizhe Li, Delin Chen, Yongyao Tan, Linyue Liang, Minjie Liu, Jingyao Liang, Shu An, Jueheng Wu, Xun Zhu, Mengfeng Li, Zhenjian He   +13 more
doaj   +1 more source

Animal models for human Metapneumovirus (HMPV) infections [PDF]

Veterinary Research, 2007
Since its detection in 2001 the human Metapneumovirus (HMPV), a member of the Paramyxoviridae family, was observed to be a serious pathogen in human respiratory infections during childhood. Meanwhile, several animal models have been established to study the virus-host interactions and pathogenic effects.
Schildgen, Oliver, Simon, Arne, Williams, John   +2 more
openaire   +3 more sources

Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes. [PDF]

PLoS Pathogens, 2015
Human metapneumovirus (HMPV), a member of the Paramyxoviridae family, is a leading cause of lower respiratory illness. Although receptor binding is thought to initiate fusion at the plasma membrane for paramyxoviruses, the entry mechanism for HMPV is ...
Reagan G Cox, Bernardo A Mainou, Monika Johnson, Andrew K Hastings, Jennifer E Schuster, Terence S Dermody, John V Williams   +6 more
doaj   +1 more source