Results 21 to 30 of about 2,894 (131)

Consensus and variations in cell line specificity among human metapneumovirus strains.

PLoS ONE, 2019
Human metapneumovirus (HMPV) has been a notable etiological agent of acute respiratory infection in humans, but it was not discovered until 2001, because HMPV replicates only in a limited number of cell lines and the cytopathic effect (CPE) is often mild.
Naganori Nao, Ko Sato, Junya Yamagishi, Maino Tahara, Yuichiro Nakatsu, Fumio Seki, Hiroshi Katoh, Aiko Ohnuma, Yuta Shirogane, Masahiro Hayashi, Tamio Suzuki, Hideaki Kikuta, Hidekazu Nishimura, Makoto Takeda   +13 more
doaj   +1 more source

HMPV Virus Outbreak: First Review in Literature

Journal of Pharmacy and Bioallied Sciences
Human metapneumovirus (HMPV), a pathogen within the Pneumoviridae family, is a notable contributor to respiratory tract infections worldwide. Identified in 2001, HMPV predominantly affects young children, the elderly, and individuals with compromised ...
Sonia Dubey, Purushottam Lal, Nitin Kumar, Rahul Tiwari, Vinej Somaraj, Sailaja Sanda, Nirvi Sharma, Heena D. Tiwari   +7 more
doaj   +1 more source

A decade of human metapneumovirus in hospitalized children with acute respiratory infection: molecular epidemiology in central Vietnam, 2007–2017

Scientific Reports, 2023
Human metapneumovirus (hMPV) can cause severe acute respiratory infection (ARI). We aimed to clarify the clinical and molecular epidemiological features of hMPV. We conducted an ARI surveillance targeting hospitalized children aged 1 month to 14 years in
Hirono Otomaru, Hien Anh Thi Nguyen, Hien Minh Vo, Michiko Toizumi, Minh Nhat Le, Katsumi Mizuta, Hiroyuki Moriuchi, Minh Xuan Bui, Duc Anh Dang, Lay-Myint Yoshida   +9 more
doaj   +1 more source

Intranasal bovine/human parainfluenza virus 3 vaccine candidates expressing human metapneumovirus wild-type or pre-fusion F protein elicit protective immunity against human metapneumovirus in hamsters

Journal of Virology
Human metapneumovirus (HMPV) and human parainfluenza virus 3 (HPIV3) are among the leading causes of severe pediatric respiratory illness worldwide, and there are no licensed vaccines.
Sirle Saul, Bibha Dahal, Cindy Luongo, Xueqiao Liu, Lijuan Yang, Celia Santos, Jin Dai, Linong Zhang, Ursula J. Buchholz, Shirin Munir   +9 more
doaj   +1 more source

Human Metapneumovirus (HMPV) Binding and Infection Are Mediated by Interactions between the HMPV Fusion Protein and Heparan Sulfate

, 2012
Human metapneumovirus (HMPV) is a major worldwide respiratory pathogen that causes acute upper and lower respiratory tract disease. The mechanism by which this virus recognizes and gains access to its target cell is still largely unknown.
Andres Chang, Ursula J. Buchholz, Rebecca Ellis Dutch, Cyril Masante   +3 more
core   +1 more source

Small Animal Models for Human Metapneumovirus: Cotton Rat is More Permissive than Hamster and Mouse

Pathogens, 2014
Human metapneumovirus (hMPV) is the second most prevalent causative agent of pediatric respiratory infections worldwide. Currently, there are no vaccines or antiviral drugs against this virus.
Yu Zhang, Stefan Niewiesk, Jianrong Li
doaj   +1 more source

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies

mBio, 2022
Human metapneumovirus (HMPV) inclusion bodies (IBs) are dynamic structures required for efficient viral replication and transcription. The minimum components needed to form IB-like structures in cells are the nucleoprotein (N) and the tetrameric ...
Kerri Beth Boggs, Kearstin Edmonds, Nicolas Cifuentes-Munoz, Farah El Najjar, Conny Ossandón, McKenna Roe, Chao Wu, Carole L. Moncman, Trevor P. Creamer, Gaya K. Amarasinghe, Daisy W. Leung, Rebecca Ellis Dutch   +11 more
doaj   +1 more source

Frequency, Burden and Pathogens of Acute Respiratory Illness in Very Preterm Infants During Infancy

Acta Paediatrica, EarlyView.
ABSTRACT Aim To describe the frequency, burden, and pathogen profile of acute respiratory illnesses (ARIs) in very preterm infants during the first year after neonatal intensive care unit (NICU) discharge. Methods Very preterm infants were followed prospectively (August 2015–January 2017) with monthly assessments of symptoms, medication use, and ...
Patricia De Gouveia Belinelo, Nada Townsi, Naomi R. Hemy, Chisha T. Sikazwe, David W. Smith, Benjamin Stoecklin, J. Jane Pillow, Graham L. Hall, Ingrid A. Laing, Shannon J. Simpson   +9 more
wiley   +1 more source

香港の冬季におけるヒトメタニューモウイルス(hMPV)の流行 [PDF]

, 2005
背景　human metapneumovirus(hMPV)は、2001年にvan den Hoogenらによってオランダで発見された新たなパラミクソウイルス科のウイルスである。性状は、Respiratory syntytial virus(RSV)に似て、冬季の呼吸器感染をおこすとされている。その後、hMPVは、世界の各地で検出、分離されているが、詳細はまだ完全には明らかになっていない。目的　RT ...
Lam, Lap-Yee, 山田, 明, Tam, John S.
core  

Phylogenetic tree of HMPV G gene sequence.

, 2019
A phylogenetic tree was constructed using the G gene sequences of 41 A2b HMPV strains detected in Sendai and 97 strains obtained from the NCBI nucleotide sequence database.
Yuichiro Nakatsu (498528), Hideaki Kikuta (3833320), Maino Tahara (6623390), Fumio Seki (498529), Yuta Shirogane (6623393), Tamio Suzuki (6623396), Makoto Takeda (296833), Junya Yamagishi (762593), Aiko Ohnuma (608392), Naganori Nao (510248), Masahiro Hayashi (608583), Hiroshi Katoh (55484), Ko Sato (697604), Hidekazu Nishimura (490362)   +13 more
core   +1 more source