Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]
PLoS Pathogens, 2010 The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin +6 more
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Henipaviruses—A constant threat to livestock and humans
PLoS Neglected Tropical Diseases, 2022 In this review, we highlight the risk to livestock and humans from infections with henipaviruses, which belong to the virus family Paramyxoviridae. We provide a comprehensive overview of documented outbreaks of Nipah and Hendra virus infections affecting
Susann Kummer, Denise-Carina Kranz
doaj +2 more sources
Probable Human Infection with a Newly Described Virus in the Family Paramyxoviridae [PDF]
Emerging Infectious Diseases, 1998 After an apparently new virus in the family Paramyxoviridae was isolated from pigs in August 1997, an investigation was carried out to assess its risk for humans. More than 250 persons with potential exposure to infected pigs were tested serologically. Two piggery workers with intense occupational exposure had high convalescent-phase antibody titers to
Kerry Chant +4 more
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mBio, 2021 Multiple enveloped RNA viruses of the family Paramyxoviridae and Pneumoviridae, like measles virus (MeV), Nipah virus (NiV), canine distemper virus (CDV), or respiratory syncytial virus (RSV), are of high clinical relevance.
Neeta Shrestha +14 more
doaj +1 more source
Revealing Berberis aristata potential as an anti-viral agent to combat Paramyxoviridae infection
Journal of Environmental Biology, 2022 Aim: To study the anti-viral activity of extracts of Berberis aristata and to scrutinize the novel lead compound present in it probably to combat Paramoxyviridae infection. Methodology: The phytochemicals present in the barks of Berberis aristata were extracted and screened by GC-MS analysis.
Y.S. Shreenivasan +3 more
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International Journal of Infectious Diseases, 2022 : Background: Following a study of predictors of superinfection in viral respiratory tract infections (VRTIs), this study analyzes the predictors of the outcome.
Benjamin Davido +10 more
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Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses
Immuno, 2023 Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009).
Brent Brown +7 more
doaj +1 more source
Interleukin-12p40 modulates human metapneumovirus-induced pulmonary disease in an acute mouse model of infection. [PDF]
PLoS ONE, 2012 The mechanisms that regulate the host immune response induced by human metapneumovirus (hMPV), a newly-recognized member of the Paramyxoviridae family, are largely unknown.
Krishnendu Chakraborty +3 more
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Meta-Transcriptomic Analysis Reveals Novel RNA Viruses in Hippocampus erectus
Viruses, 2023 Lined seahorse, Hippocampus erectus, is an important aquatic animal due to its medicinal and ornamental purposes. However, our understanding of the viral spectrum in H. erectus is still limited. Here, we studied the viruses in H.
Fan Zhang +7 more
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A Novel P/V/C Gene in a New Member of the Paramyxoviridae Family, Which Causes Lethal Infection in Humans, Horses, and Other Animals [PDF]
Journal of Virology, 1998 ABSTRACT In 1994, a new member of the family Paramyxoviridae isolated from fatal cases of respiratory disease in horses and humans was shown to be distantly related to morbilliviruses and provisionally called equine morbillivirus (K. Murray et al., Science 268:94–97, 1995).
L F, Wang +6 more
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