Results 1 to 10 of about 9,427,853 (200)

Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study

open access: yesThe Lancet Global Health, 2021
Summary: Background: Human metapneumovirus is a common virus associated with acute lower respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs associated with human metapneumovirus in children, and no licensed ...
Xin Wang, PhD   +87 more
doaj   +2 more sources

The emergence, impact, and evolution of human metapneumovirus variants from 2014 to 2021 in Spain

open access: yesJournal of Infection, 2023
BACKGROUND Human metapneumovirus (HMPV) is an important aetiologic agent of respiratory tract infection (RTI). This study aimed to describe the prevalence, genetic diversity, and evolutionary dynamics of HMPV.
Cristina Andres Verges
exaly   +2 more sources

Avian Metapneumovirus: Virology, Epidemiology, and Insights from a Comparative Analysis with Human Metapneumovirus—A Review [PDF]

open access: yesBiomolecules
Metapneumoviruses comprise a genus of negative-sense RNA viruses that cause significant respiratory disease across human and avian hosts. Human metapneumovirus (hMPV) is a globally prevalent pathogen associated with acute lower respiratory tract ...
Jason S. Hatfield   +2 more
doaj   +2 more sources

Pediatric burden and seasonality of human metapneumovirus over 5 years in Managua, Nicaragua

open access: yesInfluenza and Other Respiratory Viruses, 2022
Human metapneumovirus (hMPV) is an important cause of pediatric respiratory infection. We leveraged the Nicaraguan Pediatric Influenza Cohort Study (NPICS) to assess the burden and seasonality of symptomatic hMPV infection in children.
Kathryn Hacker
exaly   +2 more sources

A Cross-Country Evaluation of Respiratory Syncytial Virus and Human Metapneumovirus Surveillance Systems: Identifying Gaps and Best Practices for Improved Disease Monitoring. [PDF]

open access: yesRev Med Virol
ABSTRACT Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are seasonal respiratory viruses that can cause severe outcomes, particularly in older adults; however, their burden remains under‐captured. The World Health Organisation (WHO) recommends expanding surveillance over pathogens, such as RSV and hMPV, through the Mosaic ...
Martyn O   +5 more
europepmc   +2 more sources

Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance Human metapneumovirus (hMPV) is a major cause of acute lower respiratory traction infection among children, the elderly, and the immunocompromised.
Jackelyn Murray   +2 more
exaly   +2 more sources

Human metapneumovirus infection is associated with a substantial morbidity and mortality burden in adult inpatients

open access: yesHeliyon
Background Human metapneumovirus (hMPV) is one of the leading respiratory viruses. This prospective observational study aimed to describe the clinical features and the outcomes of hMPV-associated lower respiratory tract infections in adult inpatients ...
Quentin Philippot
exaly   +2 more sources

Human metapneumovirus infection of organoid-derived human bronchial epithelium represents cell tropism and cytopathology as observed in in vivo models

open access: yesMSphere
Human metapneumovirus (HMPV), a member of the Pneumoviridae family, causes upper and lower respiratory tract infections in humans. In vitro studies with HMPV have mostly been performed in monolayers of undifferentiated epithelial cells.
Bart L Haagmans   +2 more
exaly   +2 more sources

Human Metapneumovirus Infection [PDF]

open access: yesRGUHS Journal of Medical Sciences
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P S Shankar
doaj   +2 more sources

More than a Tripledemic: Influenza A Virus, Respiratory Syncytial Virus, SARS-CoV-2, and Human Metapneumovirus in Wastewater during Winter 2022–2023

open access: yesEnvironmental Science and Technology Letters, 2023
Wastewater monitoring can provide insights into respiratory disease occurrence in communities that contribute to the wastewater system. Using daily measurements of RNA of influenza A (IAV), respiratory syncytial virus (RSV), and human metapneumovirus ...
A. Boehm   +5 more
semanticscholar   +1 more source

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