Results 31 to 40 of about 9,427,853 (200)

Safety and Immunogenicity of an mRNA-Based Human Metapneumovirus and Parainfluenza Virus Type 3 Combined Vaccine in Healthy Adults

Open Forum Infectious Diseases, 2022
Background Human metapneumovirus (hMPV) and parainfluenza virus type 3 (PIV3) cause respiratory tract illness in children and the elderly. No licensed vaccines are available.
A. August, C. Shaw, Heather Lee, C. Knightly, Shiva Kalidindia, L. Chu, B. Essink, W. Seger, T. Zaks, I. Smolenov, Lori Panther   +10 more
semanticscholar   +1 more source

Human Metapneumovirus and Status Epilepticus

Pediatric Neurology Briefs, 2014
Investigators at Cincinnati Children's Hospital, OH, report 2 toddlers, ages 15 and 18 months, with human metapneumovirus (hMPV) infection who presented in status epilepticus and later developed respiratory failure.
J Gordon Millichap, John J Millichap
doaj   +1 more source

An Unusual Resurgence of Human Metapneumovirus in Western Australia Following the Reduction of Non-Pharmaceutical Interventions to Prevent SARS-CoV-2 Transmission

Viruses, 2022
Non-pharmaceutical interventions (NPIs) to reduce SARS-CoV-2 transmission disrupted respiratory virus seasonality. We examined the unusual return of human metapneumovirus (hMPV) in Western Australia following a period of absence in 2020. We analysed hMPV
D. Foley, C. Sikazwe, C. Minney-Smith, Timo Ernst, H. Moore, M. Nicol, David W Smith, A. Levy, Christopher C Blyth   +8 more
semanticscholar   +1 more source

Emergence and Potential Extinction of Genetic Lineages of Human Metapneumovirus between 2005 and 2021

mBio, 2022
Human metapneumovirus (HMPV) is one of the major causative agents of human respiratory tract infections. Monitoring of virus evolution could aid toward the development of new antiviral treatments or vaccine designs.
K. Groen, S. van Nieuwkoop, A. Meijer, B. van der Veer, J. V. van Kampen, P. Fraaij, R. Fouchier, B. G. van den Hoogen   +7 more
semanticscholar   +1 more source

The global burden of human metapneumovirus-associated acute respiratory infections in older adults: a systematic review and meta-analysis.

The Lancet Healthy Longevity
BACKGROUND The human metapneumovirus (hMPV)-associated disease burden in older adults remains under-researched. We aimed to systematically estimate the global burden of hMPV-associated disease in older adults.
D. Kulkarni, B. Cong, Mamata Jyothish Kumar Ranjini, Geetika Balchandani, Shuting Chen, Jingyi Liang, Lina González Gordon, Ajoke Sobanjo-ter Meulen, Xin Wang, You Li, R. Osei-Yeboah, K. Templeton, H. Nair   +12 more
semanticscholar   +1 more source

Risk Factors and Medical Resource Utilization of Respiratory Syncytial Virus, Human Metapneumovirus, and Influenza-Related Hospitalizations in Adults—A Global Study During the 2017–2019 Epidemic Seasons (Hospitalized Acute Respiratory Tract Infection [HARTI] Study)

Open Forum Infectious Diseases, 2021
Background Respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and influenza are respiratory pathogens leading to hospitalization in adults. Our understanding of the disease burden is limited to data from single-center or 1-season studies in
A. Falsey, E. Walsh, Stacey L. House, Yannick Vandenijck, Xiaohui Ren, S. Keim, Diye Kang, Pascal Peeters, J. Witek, G. Ispas   +9 more
semanticscholar   +1 more source

Molecular diagnosis of human metapneumovirus

The Egyptian Journal of Internal Medicine, 2012
Background The recent discovery of human metapneumovirus (hMPV) as a major respiratory pathogen has been made possible by means of reverse transcriptase-PCR (RT-PCR).
Essam S. Badawy, Sayed Mohamed Abdel Rahman, Mervat Shafik Yousef, Sayed Z. Bukhary   +3 more
doaj   +1 more source

Human Metapneumovirus Seasonality and Co-Circulation with Respiratory Syncytial Virus — United States, 2014–2024

MMWR. Morbidity and mortality weekly report
Human metapneumovirus (hMPV) infections cause acute respiratory illness and lower respiratory tract disease. Respiratory syncytial virus (RSV) is a closely related virus within the Pneumoviridae family, and hMPV and RSV infections are associated with ...
Ndey Bassin Jobe, E. Rose, A. Winn, Leah A. Goldstein, Zachary D. Schneider, Benjamin J. Silk   +5 more
semanticscholar   +1 more source

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies

mBio, 2022
Human metapneumovirus (HMPV) is a leading cause of respiratory disease among children, immunocompromised individuals, and the elderly. Currently, no vaccines or antivirals are available for the treatment of HMPV infections. ABSTRACT Human metapneumovirus
K. Boggs, Kearstin Edmonds, N. Cifuentes-Muñoz, Farah El Najjar, Conny Ossandón, McKenna Roe, Chao Wu, C. Moncman, T. Creamer, G. Amarasinghe, D. Leung, R. Dutch   +11 more
semanticscholar   +1 more source

Human Metapneumovirus, Australia, 2001–2004

Emerging Infectious Diseases, 2006
We examined 10,025 respiratory samples collected for 4 years (2001–2004) and found a 7.1% average annual incidence of human metapneumovirus. The epidemic peak of infection was late winter to spring, and genotyping showed a change in predominant viral ...
Theo P. Sloots, Ian M. Mackay, Seweryn Bialasiewicz, Kevin C. Jacob, Emily McQueen, Gerald B. Harnett, David J. Siebert, I. Brent Masters, Paul R. Young, Michael D. Nissen   +9 more
doaj   +1 more source