Results 21 to 30 of about 9,306,580 (247)

Laboratory-confirmed respiratory infections as triggers for acute myocardial infarction and stroke: a self-controlled case series analysis of national linked datasets from Scotland [PDF]

open access: yes, 2018
While acute respiratory tract infections can trigger cardiovascular events, the differential effect of specific organisms is unknown. This is important to guide vaccine policy.Using national infection surveillance data linked to the Scottish Morbidity ...
Andrew C. Hayward   +9 more
core   +3 more sources

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

open access: yesCommunications Biology, 2023
A conserved allosteric site identified on the L polymerase proteins of RSV and HMPV can be targeted by a dual-specificity, non-nucleoside inhibitor that acts by inhibiting conformational changes necessary for RNA synthesis initiation and elongation ...
Victoria A Kleiner   +14 more
semanticscholar   +1 more source

Small Hydrophobic Protein of Human Metapneumovirus Does Not Affect Virus Replication and Host Gene Expression In Vitro [PDF]

open access: yes, 2013
Human metapneumovirus (HMPV) encodes a small hydrophobic (SH) protein of unknown function. HMPV from which the SH open reading frame was deleted (HMPVΔSH) was viable and displayed similar replication kinetics, cytopathic effect and plaque size compared ...
Aarbiou, J. (Jamil)   +12 more
core   +12 more sources

Human Metapneumovirus Infections during COVID-19 Pandemic, Spain

open access: yesEmerging Infectious Diseases, 2023
We describe an unusual outbreak of respiratory infections caused by human metapneumovirus in children during the sixth wave of COVID-19 in Spain, associated with the Omicron variant. Patients in this outbreak were older than usual and showed more hypoxia
M. García-García   +7 more
semanticscholar   +1 more source

Human Metapneumovirus

open access: yesSeminars in Respiratory and Critical Care Medicine, 2007
Human metapneumovirus (hMPV) is a newly discovered paramyxovirus associated with upper and lower respiratory tract infections most commonly in young children, elderly subjects, and immunocompromised patients. hMPV can cause severe infections such as bronchiolitis and pneumonia and is responsible for 5 to 10% of hospitalizations of children suffering ...
Céline, Deffrasnes   +2 more
openaire   +4 more sources

Human Metapneumovirus Infection Induces Significant Changes in Small Noncoding RNA Expression in Airway Epithelial Cells

open access: yesMolecular Therapy: Nucleic Acids, 2014
Small noncoding RNAs (sncRNAs), such as microRNAs (miRNA), virus-derived sncRNAs, and more recently identified tRNA-derived RNA fragments, are critical to posttranscriptional control of genes.
Junfang Deng   +7 more
doaj   +1 more source

Encephalitis-Associated Human Metapneumovirus Pneumonia in Adult, Australia

open access: yesEmerging Infectious Diseases, 2015
Human metapneumovirus pneumonia, most commonly found in children, was diagnosed in an adult with encephalitis. This case suggests that testing for human metapneumovirus RNA in nasopharyngeal aspirate and cerebrospinal fluid samples should be considered ...
Anthony Fok   +4 more
doaj   +1 more source

An optimized methodology for whole genome sequencing of RNA respiratory viruses from nasopharyngeal aspirates [PDF]

open access: yes, 2018
Over the last decade, the number of viral genome sequences deposited in available databases has grown exponentially. However, sequencing methodology vary widely and many published works have relied on viral enrichment by viral culture or nucleic acid ...
Goya, Stephanie   +9 more
core   +2 more sources

Whole genome sequencing and evolution analyses of Human metapneumovirus

open access: yesVirus genes, 2023
Human metapneumovirus (HMPV) is a major pathogen of acute respiratory tract infections (ARTIs) in children. Whole genome sequence analyses could help understand the evolution and transmission events of this virus.
Tian-li Wei   +7 more
semanticscholar   +1 more source

Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system [PDF]

open access: yes, 2018
Indexación: Scopus.This work was supported by Comisión Nacional de Investigación Científica y Tecnolígica (CONICYT) N◦21151028 and FONDECYT (N◦1070352 and N◦1170964) and the Millennium Institute on Immunology and Immunotherapy (P09/016-F).Human ...
Benavente, F.M.   +8 more
core   +1 more source

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