Results 21 to 30 of about 9,427,853 (200)

Human Metapneumovirus Infection Induces Significant Changes in Small Noncoding RNA Expression in Airway Epithelial Cells

open access: yesMolecular Therapy: Nucleic Acids, 2014
Small noncoding RNAs (sncRNAs), such as microRNAs (miRNA), virus-derived sncRNAs, and more recently identified tRNA-derived RNA fragments, are critical to posttranscriptional control of genes.
Junfang Deng   +7 more
doaj   +1 more source

Structural basis for respiratory syncytial virus and human metapneumovirus neutralization

open access: yesCurrent Opinion in Virology, 2023
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) continue to be a global burden to infants, the elderly, and immunocompromised individuals.
Rose J. Miller, J. Mousa
semanticscholar   +1 more source

Encephalitis-Associated Human Metapneumovirus Pneumonia in Adult, Australia

open access: yesEmerging Infectious Diseases, 2015
Human metapneumovirus pneumonia, most commonly found in children, was diagnosed in an adult with encephalitis. This case suggests that testing for human metapneumovirus RNA in nasopharyngeal aspirate and cerebrospinal fluid samples should be considered ...
Anthony Fok   +4 more
doaj   +1 more source

Novel Human Metapneumovirus Sublineage

open access: yesEmerging Infectious Diseases, 2006
In a pediatric surveillance network, 287 (5.1%) of 5,580 specimens from patients with acute respiratory infections tested positive for human metapneumovirus (HMPV).
Barbara Huck   +5 more
doaj   +1 more source

Human Metapneumovirus Infections during COVID-19 Pandemic, Spain

open access: yesEmerging Infectious Diseases, 2023
We describe an unusual outbreak of respiratory infections caused by human metapneumovirus in children during the sixth wave of COVID-19 in Spain, associated with the Omicron variant. Patients in this outbreak were older than usual and showed more hypoxia
M. L. García-García   +7 more
semanticscholar   +1 more source

Human Metapneumovirus Reinfection in Aged Mice Recapitulates Increased Disease Severity in Elderly Humans Infected with Human Metapneumovirus

open access: yesImmunoHorizons, 2023
Human metapneumovirus (HMPV) is a leading cause of respiratory infection in adults >65 y. Nearly all children worldwide are seropositive for HMPV by age 5 y, but reinfections occur throughout life, and there is no licensed vaccine.
Olivia B. Parks   +5 more
semanticscholar   +1 more source

Human Metapneumovirus in Severe Respiratory Syncytial Virus Bronchiolitis

open access: yesEmerging Infectious Diseases, 2003
Reverse transcription-polymerase chain reaction was used to detect segments of the M (matrix), N (nucleoprotein), and F (fusion) genes of human metapneumovirus in bronchoalveolar fluid from 30 infants with severe respiratory syncytial virus bronchiolitis.
Julie Greensill   +5 more
doaj   +1 more source

Whole genome sequencing and evolution analyses of Human metapneumovirus

open access: yesVirus genes, 2023
Human metapneumovirus (HMPV) is a major pathogen of acute respiratory tract infections (ARTIs) in children. Whole genome sequence analyses could help understand the evolution and transmission events of this virus.
Tian-li Wei   +7 more
semanticscholar   +1 more source

Epidemiology of Human Metapneumovirus [PDF]

open access: yesClinical Microbiology Reviews, 2006
SUMMARY Since the discovery of human metapneumovirus (hMPV) in 2001, the virus has been identified worldwide. hMPV is a common respiratory pathogen, particularly in infants and young children. The virus is associated with both upper and lower respiratory tract infections and may be a trigger for asthma.
openaire   +2 more sources

Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins

open access: yesNature Communications, 2022
The human metapneumovirus (hMPV) fusion (F) protein is essential for viral entry and is a key target of neutralizing antibodies and vaccine development.
C. Hsieh   +6 more
semanticscholar   +1 more source

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