Results 51 to 60 of about 16,463 (206)

Human Metapneumovirus: A Largely Unrecognized Threat to Human Health

Pathogens, 2020
Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening.
Charles J. Russell, Rhiannon R. Penkert, Sonnie Kim, Julia L. Hurwitz   +3 more
doaj   +1 more source

Point‐of‐Care Testing by Multiplex‐PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation—Results of a Prospective Study

Transplant Infectious Disease, EarlyView.
Use of POCtmPCR with noninvasive samples (NPS and sputum) in LTx recipients with viral LRTI are a viable alternative to invasive BAL sampling, ABSTRACT Background Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality following lung transplantation (LTx).
Susanne Simon, Merle Sophie Kaiser, Marcus Bachmann, Gérard Krause, Jens Gottlieb   +4 more
wiley   +1 more source

Respiratory Viruses at Time of Lung Transplant and the Relationship to Primary Graft Dysfunction

Transplant Infectious Disease, EarlyView.
Primary graft dysfunction (PGD) is a form of severe and immediate post‐transplant lung injury that can lead to death. In our cohort of 229 patients undergoing lung transplantation with protocolized day 1 bronchoscopy specimens sent for respiratory viruses (RVs), RV+ status was not associated with an adjusted difference in the risk of PGD.
Laura van den Bosch, Karina Kaur, Rhea Varughese, Alim Hirji, Jason Weatherald, Justin Weinkauf, Dale Lien, Oscar Fernandez Garcia, Carlos Cervera Alvarez, Karen Doucette, Dima Kabbani, Kieran Halloran   +11 more
wiley   +1 more source

Development of a Rapid Isothermal Assay for Detection of Adenovirus Types Important in Respiratory Infections

Influenza and Other Respiratory Viruses, Volume 19, Issue 8, August 2025.
ABSTRACT Background Nucleic acid amplification tests (NAATs) for human adenoviruses (HAdVs) causing respiratory infections usually target the hexon gene. However, new HAdV types with substantial variations in the hexon gene may not be detected. Thus, we focus on NAATs based on a conserved region in the penton gene to detect all HAdV types causing ...
Benedikt Beilstein, Iris Bachmann, Martin Spiegel, Frank T. Hufert, Gregory Dame   +4 more
wiley   +1 more source

Acute Myopericarditis caused by Human Metapneumovirus [PDF]

Infection & Chemotherapy, 2016
Human metapneumovirus is known to be similar to respiratory syncytial virus. Because of an incomplete protective immune response to new genotypes, re-infection occurs frequently, especially in the elderly. However, the clinical manifestations of human metapneumovirus need to be further characterized in adults.
Min Joo Choi, Joon Young Song, Tae Un Yang, Ji Ho Jeon, Ji Yun Noh, Kyung Wook Hong, Hee Jin Cheong, Woo Joo Kim   +7 more
openaire   +2 more sources

Interferon-Mediated Response to Human Metapneumovirus Infection

Viruses, 2018
Human metapneumovirus (HMPV) is one of the leading causes of respiratory diseases in infants and children worldwide. Although this pathogen infects mainly young children, elderly and immunocompromised people can be also seriously affected. To date, there
Ifeanyi K. Uche, Antonieta Guerrero-Plata   +1 more
doaj   +1 more source

Case Report: Hematopoietic Stem Cell Transplantation to Treat Severe Acquired Aplastic Anemia in a Pediatric Kidney Transplant Recipient

Pediatric Transplantation, Volume 29, Issue 5, August 2025.
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė, Goda Elizabeta Vaitkevičienė, Karolis Ažukaitis, Augustina Jankauskienė, Jelena Rascon   +4 more
wiley   +1 more source

Recent Vaccine Development for Human Metapneumovirus [PDF]

Journal of Antivirals & Antiretrovirals, 2014
Human metapneumovirus (hMPV) and respiratory syncytial virus, its close family member, are two major causes of lower respiratory tract infection in the paediatric population. hMPV is also a common cause of worldwide morbidity and mortality in immunocompromised patients and older adults.
Thien Phan, Xiaoyong Bao, Junping Ren
openaire   +2 more sources

Clinical Evaluation of the Healgen Rapid COVID‐19 Antigen Test as a Point‐of‐Care Diagnostic Tool

Immunity, Inflammation and Disease, Volume 13, Issue 7, July 2025.
ABSTRACT Background Development of readily available Rapid COVID‐19 Antigen tests essential for promptly identifying SARS‐CoV2 infection and preventing its spread. Methods This study evaluated the clinical performance of the Healgen Rapid COVID‐19 antigen test as a point‐of‐care diagnostic tool with 806 evaluable subjects who were within 6 days post ...
Stephen A. Young, Hua Zhang, Jose Rodriguez, David Mishkin, Ward Paine, Li Seyfried, LaTisha Hargrove, Dennis L. Broyles, Chermaen Lindberg, Anurag Purushothaman, Stacey House   +10 more
wiley   +1 more source

Human metapneumovirus infection

, 2007
Initially, human metapneumovirus (hMPV) was isolated from children with clinical symptoms of respiratory syncytial virus (RSV) infection in whom RSV could not be detected. Since then, numerous reports have described the detection of hMPV in clinical specimens from children, adults and the elderly (both immunocompetent and immunocompromised patients ...
Adilia Warris, Ronald de Groot
openaire   +2 more sources