Results 71 to 80 of about 29,027 (201)

The synthetic bacterial lipopeptide Pam3CSK4 modulates respiratory syncytial virus infection independent of TLR activation [PDF]

, 2010
Respiratory syncytial virus (RSV) is an important cause of acute respiratory disease in infants, immunocompromised subjects and the elderly. However, it is unclear why most primary RSV infections are associated with relatively mild symptoms, whereas some
A Trkola, AGSC Jansen, Albert D. M. E. Osterhaus, B Ten Berge, B Wolf, CR Rossi, D Droemann, D. Tien Nguyen, DR Murdoch, EAF Simoes, G McGillivary, G Meng, H Kumar, HE Davis, I Lazar, J Münch, J Zhang, James E. Crowe, JM Hament, JM Hament, JM Hament, K Ampofo, K Hashimoto, K Konopka, KA Neilson, Karl-Heinz Wiesmüller, KL O'Brien, KW Boehme, L Duttweiler, LK Hallak, LK Hallak, LK Hallak, Lot de Witte, M de Graaf, M Parcina, Martin Ludlow, MAWP De Jong, MB Elliott, MG Semple, MS Jin, NR Roan, OD Timmons, P Ebbesen, PL Collins, PL Collins, RA Lamb, RD De Vries, Rik L. de Swart, RM Chanock, RM Chanock, RS Van Binnendijk, S Akira, S Khan, S Khan, S Phipps, S Thibault, S Thibault, SA Madhi, SD Allard, Selma Yüksel, T Heikkinen, T Hussell, Teunis B. H. Geijtenbeek, U Buwitt-Beckmann, V Avadhanula, V Lombardi, V Regueiro, Y Ogawa   +67 more
core   +13 more sources

Torque Teno Virus Levels During Viral Respiratory Infections: The Interplay With Immune Dysregulation and Coagulopathy Biomarkers

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Torque teno virus (TTV) is a ubiquitous, nonenveloped DNA virus of the Anelloviridae family and a proposed surrogate marker of immune competence. Although nonpathogenic, its replication reflects host immune status and is associated with immune dysregulation during respiratory viral infections (RVIs).
Roberto Ferrarese, Pietro Giorgio Spezia, Sara Boutahar, Angelo Paolo Genoni, Gabriele Arcari, Gaia Zambon, Maria Dolci, Sara D'alessandro, Giuseppe Sberna, Serena Delbue, Nicasio Mancini, Fabrizio Maggi, Lucia Signorini, Federica Novazzi   +13 more
wiley   +1 more source

Human Metapneumovirus Genetic Variability, South Africa

Emerging Infectious Diseases, 2005
The molecular epidemiology and genetic diversity of the human metapneumovirus (hMPV) were characterized for a 3-year period (2000–2002) from viruses that were identified in South Africa.
Herbert P. Ludewick, Yacine Abed, Nadia van Niekerk, Guy Boivin, Keith P. Klugman, Shabir A. Madhi   +5 more
doaj   +1 more source

Clinical significance of human metapneumovirus detection in critically ill adults with lower respiratory tract infections

Annals of Intensive Care, 2023
Background Unlike other viruses, the pathogenicity of human metapneumovirus (hMPV) in adults remains uncertain. To address this question, a retrospective monocentric cohort including all patients admitted to ICU with hMPV infection between January 1 ...
Natacha Kapandji, Michael Darmon, Sandrine Valade, Maud Salmona, Jérôme Legoff, Lara Zafrani, Elie Azoulay, Virginie Lemiale   +7 more
doaj   +1 more source

The impact of co-infection of influenza A virus on the severity of Middle East Respiratory Syndrome Coronavirus [PDF]

, 2017
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Alfaraj, Sarah H., Altwaijri, Talal A., Alzahrani, Nojoom A., Memish, Ziad A.   +4 more
core   +1 more source

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

MedComm, Volume 7, Issue 2, February 2026.
This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu, Duanmiao Si, Dingwei Lei, Xiaoxue Xie, Yongge Li, Han Wen   +5 more
wiley   +1 more source

Human metapneumovirus in Southern Brazil

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Infections caused by respiratory viruses are important problems worldwide, especially in children. Human metapneumovirus (hMPV) is a respiratory pathogen and causes severe infections with nonspecific symptoms.
Tatiana Schäffer Gregianini, Claudete Farina Seadi, Ivone Menegolla, Letícia Garay Martins, Nilo Ikuta, Jonas Michel Wolf, Vagner Ricardo Lunge   +6 more
doaj   +1 more source

Interferon-Mediated Response to Human Metapneumovirus Infection

Viruses, 2018
Human metapneumovirus (HMPV) is one of the leading causes of respiratory diseases in infants and children worldwide. Although this pathogen infects mainly young children, elderly and immunocompromised people can be also seriously affected. To date, there
Ifeanyi K. Uche, Antonieta Guerrero-Plata   +1 more
doaj   +1 more source

Performance of diagnostic tests to detect respiratory viruses in older adults. [PDF]

, 2010
The performance of 4 laboratory methods for diagnosis of viral respiratory tract infections (RTI) in older adults was evaluated. Seventy-four nasopharyngeal (NP) swab specimens were obtained from 60 patients with RTI at a long-term care facility over 2 ...
Caram, Lauren B, Hymas, Weston C, Petti, Cathy A, Polage, Christopher R, Schmader, Kenneth, She, Rosemary C, Taggart, Edward W, Woods, Christopher W   +7 more
core  

Interaction analysis of non‐bacterial respiratory pathogens during and after the coronavirus disease 2019 pandemic in two cities along the eastern coast of China

Pediatric Investigation, Volume 10, Issue 1, Page 47-59, February 2026.
What is Known • Co‐infections can influence pathogen replication, disease severity, and the duration of illness. • Co‐infection patterns and temporal correlations have been characterized among various respiratory viruses and atypical pathogens. What is New • A consistent negative correlation between influenza B and Mycoplasma pneumoniae suggests ...
Wanxian Ye, Jishan Zheng, Yungang Yang, Xinyue Song, Xiang Yuan, Lan Yang, Jian Yu, Hailin Zhang, Shunhang Wen   +8 more
wiley   +1 more source