Results 131 to 140 of about 180,411 (308)

The Role of Bacterial Proteases From the Microbiome in Human Disease [PDF]

Ying‐Chiang J. Lee
openalex   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Prevalence of oxalotrophy in the human microbiome. [PDF]

BMC Genomics
Junier T, Palmieri F, Ubags ND, Trompette A, Koutsokera A, Junier P, Pagni M, Neuenschwander S.   +7 more
europepmc   +2 more sources

mSphere of Influence: Frameshift—a Vision for Human Microbiome Research

, 2020
Ariangela J. Kozik
openalex   +1 more source

Candidate probiotic Lactiplantibacillus plantarum HNU082 rapidly and convergently evolves within human, mice, and zebrafish gut but differentially influences the resident microbiome [PDF]

, 2021
Shi Huang, Shuaiming Jiang, Dongxue Huo, Celeste Allaband, Mehrbod Estaki, Victor Cantu, Pedro Belda‐Ferre, Yoshiki Vázquez‐Baeza, Qiyun Zhu, Chenchen Ma, Congfa Li, Amir Zarrinpar, Yang‐Yu Liu, Rob Knight, Jiachao Zhang   +14 more
openalex   +1 more source

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

Advanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang, Xinyun Li, Yong Wang, Chuhe Yang, Xiaopei Gao, Ke Zhu, Yihang Ren, Jingxin Li, Chuanyong Liu, Bing Xue   +9 more
wiley   +1 more source

Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters

, 2012
J. Graessler, Youwen Qin, Huanzi Zhong, Jialun Zhang, Julio Licínio, Ma‐Li Wong, Aimin Xu, Triantafyllos Chavakis, Alexander Benjamin Bornstein, Monika Ehrhart‐Bornstein, Valéria Lamounier‐Zepter, Tobias Lohmann, Tiffany M. Wolf, Stefan R. Bornstein   +13 more
openalex   +2 more sources

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

CACLENS: A Multitask Deep Learning System for Enzyme Discovery

Advanced Science, EarlyView.
CACLENS, a multimodal and multi‐task deep learning framework integrating cross‐attention, contrastive learning, and customized gate control, enables reaction type classification, EC number prediction, and reaction feasibility assessment. CACLENS accelerates functional enzyme discovery and identifies efficient Zearalenone (ZEN)‐degrading enzymes.
Xilong Yi, Yingzhu Tan, Huikang Lin, Guoqing Zhang, Ye Tian, Aibo Wu   +5 more
wiley   +1 more source

The Influence of the Use of Face Masks During the COVID-19 Pandemic on the Human Microbiome – A Mini-Review [PDF]

, 2021
Izabela Chudzicka-Strugała, Iwona Cybulska, Grzegorz Brudecki, Barbara Zwoździak   +3 more
openalex   +1 more source