Results 131 to 140 of about 239,936 (333)
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Dysbiosis of the bacterial and fungal microbiome has been increasingly implicated in the pathogenesis of chronic rhinosinusitis (CRS). This study explores the relationship between microbiome and mycobiome biodiversity and type 2 (T2) versus non‐type 2 (NT2) inflammation.
Hong‐Ho Yang +13 more
wiley +1 more source
Hosts, microbiomes, and the evolution of critical windows
Evolution Letters, Volume 6, Issue 6, Page 412-425, December 2022., 2022 Abstract The absence of microbial exposure early in life leaves individuals vulnerable to immune overreaction later in life, manifesting as immunopathology, autoimmunity, or allergies. A key factor is thought to be a “critical window” during which the host's immune system can “learn” tolerance, and beyond which learning is no longer possible.
C. Jessica E. Metcalf +3 more
wiley +1 more source
A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation
Angewandte Chemie, EarlyView.The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu +9 more
wiley +2 more sources
Describing the Persistence Landscape for Introducing Microbes into Complex Communities [PDF]
arXivThe introduction of non-native organisms into complex microbiome communities holds enormous potential to benefit society. However, microbiome engineering faces several challenges including successful establishment of the organism into the community, its persistence in the microbiome to serve a specified purpose, and constraint of the organism and its ...
arxiv
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Particulate matter ⩽2.5 µm in diameter (PM2.5) and its role in chronic rhinosinusitis (CRS) pathogenesis have gained heightened attention. We previously demonstrated that PM2.5 exposure may bias the nasal mucosa in CRS toward a Type 2 inflammatory pathway.
Rory J. Lubner +5 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Angewandte Chemie, EarlyView.Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog +8 more
wiley +2 more sources
A Catalog of Reference Genomes from the Human Microbiome [PDF]
, 2010 William Nelson +82 more
openalex +1 more source
Food Bioengineering, Volume 1, Issue 3-4, Page 252-263, December 2022., 2022 Lactiplantibacillus plantarum X7022 is a novel strain isolated from the traditional fermented stinky tofu brine. L. plantarum X7022 could alleviate constipation by improving defection indices. L. plantarum X7022 regulated gut microbiota dysbiosis in the two different constipation models.
Xingye Chen +5 more
wiley +1 more source
Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances
Animal Models and Experimental Medicine, EarlyView.In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong +7 more
wiley +1 more source