Results 131 to 140 of about 8,462,270 (351)

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

Randomised clinical trial: effect of low-FODMAP rye bread versus regular rye bread on the intestinal microbiota of irritable bowel syndrome patients: association with individual symptom variation

open access: yesBMC Nutrition, 2019
Background A low intake of Fermentable, Oligo-, Di-, Mono-saccharides and Polyols (FODMAPs) is effective in the symptom control of irritable bowel syndrome (IBS) patients but may exert negative effects on the intestinal microbiota.
Reijo Laatikainen   +7 more
doaj   +1 more source

Geography, Ethnicity or Subsistence-Specific Variations in Human Microbiome Composition and Diversity

open access: yesFrontiers in Microbiology, 2017
One of the fundamental issues in the microbiome research is characterization of the healthy human microbiota. Recent studies have elucidated substantial divergences in the microbiome structure between healthy individuals from different race and ethnicity.
V. Gupta, Sandip Paul, C. Dutta
semanticscholar   +1 more source

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

open access: yesAdvanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song   +16 more
wiley   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

Reporting guidelines for human microbiome research: the STORMS checklist

open access: yesNature Network Boston, 2021
C. Mirzayi   +102 more
semanticscholar   +1 more source

Exploring the Human Microbiome: The Potential Future Role of Next-Generation Sequencing in Disease Diagnosis and Treatment

open access: yesFrontiers in Immunology, 2019
The interaction between the human microbiome and immune system has an effect on several human metabolic functions and impacts our well-being. Additionally, the interaction between humans and microbes can also play a key role in determining the wellness ...
M. A. Malla   +5 more
semanticscholar   +1 more source

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