Results 141 to 150 of about 296,797 (348)
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
A Catalog of Reference Genomes from the Human Microbiome [PDF]
, 2010 William Nelson +82 more
openalex +1 more source
Advanced Science, EarlyView.The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi +15 more
wiley +1 more source
Human microbiome science: vision for the future, Bethesda, MD, July 24 to 26, 2013 [PDF]
, 2014 A conference entitled ‘Human microbiome science: Vision for the future’ was organized in Bethesda, MD from July 24 to 26, 2013. The event brought together experts in the field of human microbiome research and aimed at providing a comprehensive overview ...
Mazmanian, Sarkis K., Ravel, Jacques
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Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism
Advanced Science, EarlyView.Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang +4 more
wiley +1 more source
Benchmarking urine storage and collection conditions for evaluating the female urinary microbiome. [PDF]
, 2019 Standardized conditions for collection, preservation and storage of urine for microbiome research have not been established. We aimed to identify the effects of the use of preservative AssayAssure® (AA), and the effects of storage time and temperatures ...
Brubaker, Linda +8 more
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Advanced Science, EarlyView.Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang +16 more
wiley +1 more source
Advanced Science, EarlyView.In this work, “inorganic‐free” nanosheets, named PNSE are developed using template‐based synthesis technology. The functionalized organic nanosheets exhibit low cytotoxicity, mild protein adsorption, and potent binding efficacy to epithelial sEVs.
Zhaoxu Tu +11 more
wiley +1 more source
npj Biofilms and MicrobiomesImbalanced microbiota may contribute to the pathophysiology of irritable bowel syndrome (IBS), thus fecal microbiota transplantation (FMT) has been suggested as a potential treatment.
Anna K. Hartikainen +9 more
doaj +1 more source