Results 191 to 200 of about 239,936 (333)

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

The human microbiome and cancer: a diagnostic and therapeutic perspective. [PDF]

Cancer Biol Ther, 2023
Kandalai S, Li H, Zhang N, Peng H, Zheng Q.   +4 more
europepmc   +1 more source

Structural Insights Into Galectin‐3 Recognition of a Selenoglycomimetic

ChemMedChem, EarlyView.
Galectin‐3, a β‐galactoside‐binding protein, plays a pivotal role in fibrosis and carcinogenesis. We explore the molecular recognition of a seleno‐digalactoside, modified with a benzyl group (SeDG‐Bn), as a potent Gal‐3 inhibitor. Using nuclear magnetic resonance and molecular dynamics simulations, we present a 3D model of the SeDG‐Bn/Gal‐3 complex ...
Maria Pia Lenza, Cristina Di Carluccio, Ferran Nieto‐Fabregat, Luciano Pirone, Rita Russo, Sonia Di Gaetano, Domenica Capasso, Alessia Stornaiuolo, Alfonso Iadonisi, Michele Saviano, Roberta Marchetti, Emilia Pedone, Alba Silipo   +12 more
wiley   +1 more source

Similarity of drug targets to human microbiome metaproteome promotes pharmacological promiscuity. [PDF]

Pharmacogenomics J
Beaudoin CA, Norget S, Omran Z, Hala S, Daqeeq AH, Burnet PWJ, Blundell TL, van Tonder AJ.   +7 more
europepmc   +1 more source

Combined metagenomic and phenomic approaches identify a novel salt tolerance gene from the human gut microbiome [PDF]

, 2014
Eamonn P. Culligan, Julian R. Marchesi, Colin Hill, Roy D. Sleator   +3 more
openalex   +1 more source

Distinct Patterns of Dynamical Regulation in Passive Sensor Data Following Binge and Purge Behaviors

International Journal of Eating Disorders, EarlyView.
ABSTRACT Background Binge eating is a cardinal symptom of binge‐eating disorder (BED) and bulimia nervosa (BN), while recurrent purging is specific to BN (American Psychiatric Association, 2022). These behaviors are associated with health consequences (e.g., gastrointestinal, cardiovascular, and metabolic problems; Sheehan & Herman, 2015). The distress‐
Jonathan E. Butner, Laura M. Thornton, Robyn E. Kilshaw, Rachael E. Flatt, Qinxin Shi, Pascal R. Deboeck, Jenna Tregarthen, Stuart Argue, Brian R. W. Baucom, Cynthia M. Bulik   +9 more
wiley   +1 more source

Expanding the β-Lactamase Family in the Human Microbiome. [PDF]

Adv Sci (Weinh)
Jia B, Baek JH, Lee JK, Sun Y, Kim KH, Jung JY, Jeon CO.   +6 more
europepmc   +1 more source

The Human Microbiome and Its Role in Musculoskeletal Disorders. [PDF]

Genes (Basel), 2023
Aboushaala K, Wong AYL, Barajas JN, Lim P, Al-Harthi L, Chee A, Forsyth CB, Oh CD, Toro SJ, Williams FMK, An HS, Samartzis D.   +11 more
europepmc   +1 more source

Insights from Characterizing Extinct Human Gut Microbiomes

, 2012
Raúl Y. Tito, Dan Knights, Jessica L. Metcalf, Alexandra J. Obregón-Tito, Lauren M. Cleeland, Fares Z. Najar, Bruce A. Roe, Karl J. Reinhard, Kristin D. Sobolik, Samuel Belknap, Morris W. Foster, Paul Spicer, Rob Knight, Cecil M. Lewis   +13 more
openalex   +2 more sources

Unlocking the healthy human microbiome: Redefining core microbial signatures. [PDF]

Acta Pharm Sin B
Xia S, Jiang D, Zhou Q, Lyu H, Voigt AY, Zhou X, Zhou Z, Huang Y.   +7 more
europepmc   +1 more source