Results 201 to 210 of about 213,516 (305)

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

Annals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh, Xochitl C. Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A. Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios   +7 more
wiley   +1 more source

MicroMap: a network visualisation resource for human microbiome metabolism. [PDF]

NPJ Biofilms Microbiomes
Thinnes CC, Waschkowitz R, Courtney E, Culligan E, Fahy K, Ferrazza RAM, Ferris C, Lagali A, Lane R, Maye C, Murphy O, Noone D, Ryan S, Bet M, Corr MC, Cummins H, Hackett D, Healy E, Kulczycka N, Lang N, Madden L, McHugh L, Pyne I, Varley C, Harkin N, Meade R, O'Donnell G, Nap B, Martinelli F, Heinken A, Thiele I.   +30 more
europepmc   +1 more source

A framework for human microbiome research.

, 2020
Human Microbiome Project Consortium,,
core  

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source

STROBE-causal machine learning for the human microbiome: systematic review on methodological innovations and validation frameworks. [PDF]

Front Microbiol
Khelfaoui I, Wang W, Shehata AI, Meskher H, El Basuini MF, Mohamed AMA, Abouelenein MF, Degha HE, Alhoshy M, Teiba II, Mahmoud O, Mahmoud SS.   +11 more
europepmc   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Editorial: Microbial therapeutics: harnessing the human microbiome for disease treatment and prevention. [PDF]

Front Med Technol
Bhojiya AA, Saurabh A, Jain D.
europepmc   +1 more source

Beyond microbial abundance: metadata integration enhances disease prediction in human microbiome studies. [PDF]

Front Microbiol
Goncalves AR, Ranganathan H, Valdes C, Zhu H, Zhang B, Kok CR, Martí JM, Mulakken NJ, Thissen JB, Jaing C, Be NA.   +10 more
europepmc   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

How is the human microbiome linked to kidney stones? [PDF]

Front Cell Infect Microbiol
Pei X, Liu M, Yu S.
europepmc   +1 more source