Results 161 to 170 of about 564,378 (281)

Coral Restoration in the Omics Era: Development of Point‐of‐Care Tools for Monitoring Disease, Reproduction, and Thermal Stress

BioEssays, EarlyView.
Shown are different multi‐omics approaches that are used to identify potential biomarkers of coral health and disease. The integration of these data streams, using cutting‐edge molecular diagnostic technologies, including colorimetric dipsticks, lateral flow assays, and colorimetric LAMP (loop‐mediated isothermal amplification), holds the promise to ...
Erin E. Chille, Timothy G. Stephens, Shrinivas Nandi, Haoyu Jiang, Michael J. Gerdes, Olivia M. Williamson, Alexander Neufeld, Phanor Montoya‐Maya, Debashish Bhattacharya   +8 more
wiley   +1 more source

Assessing Engraftment Following Fecal Microbiota Transplant [PDF]

arXiv
Fecal Microbiota Transplant (FMT) is an FDA approved treatment for recurrent Clostridium difficile infections, and is being explored for other clinical applications, from alleviating digestive and neurological disorders, to priming the microbiome for cancer treatment, and restoring microbiomes impacted by cancer treatment.
arxiv  

Pan‐cancer analysis shapes the understanding of cancer biology and medicine

Cancer Communications, EarlyView.
Abstract Advances in multi‐omics datasets and analytical methods have revolutionized cancer research, offering a comprehensive, pan‐cancer perspective. Pan‐cancer studies identify shared mechanisms and unique traits across different cancer types, which are reshaping diagnostic and treatment strategies.
Xiaoping Cen, Yuanyuan Lan, Jiansheng Zou, Ruilin Chen, Can Hu, Yahan Tong, Chen Zhang, Jingyue Chen, Yuanmei Wang, Run Zhou, Weiwei He, Tianyu Lu, Fred Dubee, Dragomirka Jovic, Wei Dong, Qingqing Gao, Man Ma, Youyong Lu, Yu Xue, Xiangdong Cheng, Yixue Li, Huanming Yang   +21 more
wiley   +1 more source

Pretrained-Guided Conditional Diffusion Models for Microbiome Data Analysis [PDF]

arXiv
Emerging evidence indicates that human cancers are intricately linked to human microbiomes, forming an inseparable connection. However, due to limited sample sizes and significant data loss during collection for various reasons, some machine learning methods have been proposed to address the issue of missing data.
arxiv  

Ethnomedicinal uses, phytochemistry, pharmacological activities, and toxicology of the subfamily Gomphrenoideae (Amaranthaceae): A comprehensive review

Chemistry &Biodiversity, Accepted Article.
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves, Giulia Cristina Andreoli de Souza, Alvaro Jose Hernandez Tasco, Marcos Jose Salvador   +3 more
wiley   +1 more source

The Exercise Microbiome Project: An 8 week Cardiovascular Intervention on the Human Gut Microbiome

, 2019
Arron Shiffer, Anthony Santos, Kyle N. Winfree, Shari Kyman, Emily K. Cope, J. Gregory Caporaso, Dierdra Bycura   +6 more
openalex   +1 more source

Cold‐Adapted Lipid A from Polaribacter sp. SM1127: A Study of Structural Heterogeneity and Immunostimulatory Properties

ChemBioChem, EarlyView.
This analysis reveals structural heterogeneity in the lipopolysaccharide lipid A from the cold‐adapted Gram‐negative bacterium Polaribacter sp. SM1127, with variations in fatty acid chain number, length, branching, saturation, and hydroxylation degree, likely aiding bacterial adaptation to cold environmental stressors. Lipopolysaccharide is shown to be
Roberta Cirella, Emanuela Andretta, Luca De Simone Carone, Francesca Olmeo, Mei‐Ling Sun, Yu‐Zhong Zhang, Marcello Mercogliano, Antonio Molinaro, Alba Silipo, Flaviana Di Lorenzo   +9 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Structural Insights Into Galectin‐3 Recognition of a Selenoglycomimetic

ChemMedChem, EarlyView.
Galectin‐3, a β‐galactoside‐binding protein, plays a pivotal role in fibrosis and carcinogenesis. We explore the molecular recognition of a seleno‐digalactoside, modified with a benzyl group (SeDG‐Bn), as a potent Gal‐3 inhibitor. Using nuclear magnetic resonance and molecular dynamics simulations, we present a 3D model of the SeDG‐Bn/Gal‐3 complex ...
Maria Pia Lenza, Cristina Di Carluccio, Ferran Nieto‐Fabregat, Luciano Pirone, Rita Russo, Sonia Di Gaetano, Domenica Capasso, Alessia Stornaiuolo, Alfonso Iadonisi, Michele Saviano, Roberta Marchetti, Emilia Pedone, Alba Silipo   +12 more
wiley   +1 more source

MetaTrass: A high‐quality metagenome assembler of the human gut microbiome by cobarcoding sequencing reads

iMeta, Volume 1, Issue 4, December 2022., 2022
We developed a tool to get high‐quality genomes with high taxonomic resolution by combining the cobarcoding information with public references. Compared with the conventional combination strategies, our pipeline generated a large number of high‐quality genomes for the human microbial cobarcoding data sets. Abstract Metagenomic evidence of great genetic
Yanwei Qi, Shengqiang Gu, Yue Zhang, Lidong Guo, Mengyang Xu, Xiaofang Cheng, Ou Wang, Ying Sun, Jianwei Chen, Xiaodong Fang, Xin Liu, Li Deng, Guangyi Fan   +12 more
wiley   +1 more source