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A framework for human microbiome research. [PDF]
A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a ...
Human Microbiome Project Consortium
core +10 more sources
Elevated rates of horizontal gene transfer in the industrialized human microbiome
Industrialization has impacted the human gut ecosystem, resulting in altered microbiome composition and diversity. Whether bacterial genomes may also adapt to the industrialization of their host populations remains largely unexplored.
Mathieu Groussin +2 more
exaly +2 more sources
Structure, function and diversity of the healthy human microbiome
Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although diet, environment, host genetics
The Human Microbiome Project Consortium, * +1 more
exaly +1 more source
The Human Microbiome Project: A Community Resource for the Healthy Human Microbiome
This manuscript describes the NIH Human Microbiome Project, including a brief review of human microbiome research, a history of the project, and a comprehensive overview of the consortium's recent collection of publications analyzing the human microbiome.
Dirk Gevers +2 more
exaly +9 more sources
The human microbiome (glossary in Appendix 1, available at [www.cmaj.ca/lookup/suppl/doi:10.1503/cmaj.141072/-/DC1][1]) comprises hundreds of previously known and newly discovered microbial species living in distinct communities adapted to specific anatomic sites.[1][2] In healthy adults ...
Bryan, Coburn, David S, Guttman
openaire +3 more sources
The sequencing of the human genome has driven the study of human biology in a significant way and enabled the genome-wide study to elucidate the molecular basis of complex human diseases. Recently, the role of microbiota on human physiology and health has received much attention.
J, Rajendhran, P, Gunasekaran
openaire +2 more sources
In 2011, at the Society for Integrative Oncology's international meeting in Cleveland, Ohio, Francis Collins, PhD, head of the National Institutes of Health, shocked the audience when he asserted that although his work in the human genome was exciting, he was more impressed by the potential represented by the National Institutes of Health's investment ...
Plotnikoff, Gregory A., Riley, David
openaire +2 more sources
A microbiome is defined as the aggregate of all microbiota that reside in human digestive system and other tissues. This microbiota includes viruses, bacteria, fungi that live in various human organs and tissues like stomach, guts, oesophagus, mouth cavity, urinary tract, vagina, lungs, and skin.
Mohammad Menati Rashno +3 more
openaire +2 more sources
Ancient human microbiomes [PDF]
Very recently, we discovered a vast new microbial self: the human microbiome. Our native microbiota interface with our biology and culture to influence our health, behavior, and quality of life, and yet we know very little about their origin, evolution, or ecology.
Christina Warinner +3 more
openaire +3 more sources
The Human Oral Microbiome [PDF]
ABSTRACT The human oral cavity contains a number of different habitats, including the teeth, gingival sulcus, tongue, cheeks, hard and soft palates, and tonsils, which are colonized by bacteria. The oral microbiome is comprised of over 600 prevalent taxa at the species level, with distinct subsets predominating at
Dewhirst, Floyd E. +7 more
openaire +3 more sources

