Results 41 to 50 of about 23,384 (208)
Evaluation of 16S rDNA-Based Community Profiling for Human Microbiome Research
, 2012 The Human Microbiome Project will establish a reference data set for analysis of the microbiome of healthy adults by surveying multiple body sites from 300 people and generating data from over 12,000 samples.
Jumpstart Consortium Human Microbiome Project Data Generation Working Group (614229)
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Changes in the microbiome of a human and in the simulator of human intestinal microbial ecosystem (SHIME®) in response to a diet and probiotic supplementation [PDF]
, 2023 Background. The Simulator of Human Intestinal Microbial Ecosystem (SHIME®) is used to study the behavior of a human microbiome in response to various factors.
Zielińska, Dorota +7 more
core
Aging, Frailty, and the Microbiome - How Dysbiosis Influences Human Aging and Disease
, 2021 The human gut microbiome is a collection of bacteria, protozoa, fungi, and viruses that coexist in our bodies and are essential in protective, metabolic, and physiologic functions of human health.
McCormick, Beth A., Haran, John P
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell +7 more
wiley +1 more source
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative
, 2021 Background: In recent years, human microbiota, especially gut microbiota, have emerged as an important yet complex trait influencing human metabolism, immunology, and diseases.
김한나, 김형래
core +2 more sources
The Human Microbiome Project [PDF]
Indian Journal of Microbiology, 2012 The Human Microbiome project (National Institute of Health, USA) has just been completed and information generated from this project was published on June 14, 2012 in Nature and PLoS journals. This project, which consists of a consortium of scientists from nearly 80 universities and scientific institutions, aims to reveal the myriad of microbial ...
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova +4 more
wiley +1 more source