Results 231 to 240 of about 133,927 (289)

Application of image guided analyses to monitor fecal microbial composition and diversity in a human cohort. [PDF]

open access: yesSci Rep
Zafeiropoulou K   +11 more
europepmc   +1 more source

SynCom‐mediated herbicide degradation activates microbial carbon metabolism in soils

open access: yesiMeta, EarlyView.
Extensive herbicide residues in the black soil of northeastern China are considered a significant agricultural pollution threat, yet effective bioremediation of this complex and persistent mixture remains a challenge. We provided an herbicide degradation and ecosystem regulation model of SynCom in soil. We also demonstrated the effectiveness of SynCom “
Yuxiao Zhang   +12 more
wiley   +1 more source

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

open access: yesiMeta, EarlyView.
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang   +12 more
wiley   +1 more source

In vivo systematic analysis of microbiota-prebiotic crosstalk reveals a synbiotic that effectively ameliorates DSS-induced colitis in mice. [PDF]

open access: yesGut Microbes
Peng Q   +15 more
europepmc   +1 more source

Gut microbial‐derived 3,4‐dihydroxyphenylacetic acid ameliorates reproductive phenotype of polycystic ovary syndrome

open access: yesiMeta, EarlyView.
By integrating multi‐level and multi‐omics analyses, we identify 3,4‐dihydroxyphenylacetic acid (DHPAA), a gut microbiota‐derived degradation product of dietary flavonoids, as a key bioactive end‐product responsible for the beneficial effects against polycystic ovary syndrome (PCOS).
Pan Li   +22 more
wiley   +1 more source

Ecologically expanding the One Health framework to unify the microbiome sciences. [PDF]

open access: yesmBio
Ginnan N   +7 more
europepmc   +1 more source

Akkermansia muciniphila‐derived hypoacylated rough‐type lipopolysaccharides alleviate diet‐induced obesity via activation of TLR4−IL‐23−IL‐22 immune axis

open access: yesiMeta, EarlyView.
This study demonstrates that hypoacylated, rough‐type lipopolysaccharides (LPS) derived from Akkermansia muciniphila strain HW07 (ALPS) alleviates diet‐induced obesity. ALPS acts as a weak TLR4 agonist and significantly reduces weight gain, improves metabolic parameters, and restores gut barrier integrity in obese mice.
Li Sun   +14 more
wiley   +1 more source

Functional metagenomics reveals novel antibiotic resistomes in polar soils

open access: yesiMeta, EarlyView.
Using a robust functional metagenomics approach, we demonstrated that polar environments are important reservoirs of novel antibiotic resistance genes (ARGs). DNA was initially extracted from cultured bacterial consortia in the polar soils and recombined into plasmid vectors and then transformed into Escherichia coli (E.
Xiuqin Xie   +10 more
wiley   +1 more source

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