Results 231 to 240 of about 149,474 (293)

Composition and Function of Gut Microbiome: From Basic Omics to Precision Medicine. [PDF]

open access: yesGenes (Basel)
Ma Y   +10 more
europepmc   +1 more source

BIOME cohort: Multi‐system microbiome dynamics and clinical outcomes in massive burn injury patients

open access: yesiMeta, EarlyView.
Massive burn injuries (MBIs) are associated with high mortality and disability rates, primarily due to microbial‐driven sepsis from extensive skin barrier loss and subsequent scar formation. This makes MBI a compelling model for studying multi‐system microbial dysbiosis following skin barrier destruction.
Runzhi Huang   +72 more
wiley   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

open access: yesInterdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu   +6 more
wiley   +1 more source

Gut microbiome-mediated transformation of dietary phytonutrients is associated with health outcomes. [PDF]

open access: yesNat Microbiol
Zhang L   +10 more
europepmc   +1 more source

Decoding temporal miRNA signatures of semen under in vitro exposure for forensic time since deposition estimation using machine learning‐driven modeling

open access: yesInterdisciplinary Medicine, EarlyView.
This study develops a novel miRNA‐based framework for estimating the time since deposition of semen stains, combining small RNA sequencing with machine learning. Time‐dependent miRNA modules were identified using Mfuzz clustering and WGCNA, followed by a multi‐stage feature selection pipeline that reduced 261 candidate miRNAs to a minimal 7‐miRNA panel.
Meiming Cai   +11 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

Fecal butyrate and deoxycholic acid quantitation for rapid assessment of the gut microbiome. [PDF]

open access: yesPLoS One
Mullowney MW   +13 more
europepmc   +1 more source

Association between the gut microbiome and neurodevelopmental outcomes in infants with congenital heart disease: A prospective cohort study

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with congenital heart disease are at risk for poor neurodevelopment. The gut microbiome may influence neurodevelopmental outcomes through the gut‐brain axis. This study investigated the association of early‐life gut microbiome with neurodevelopmental outcomes.
Michael P. Fundora   +11 more
wiley   +1 more source

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