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The Human Microbiome Project: Beginning and Future Status [PDF]

open access: goldAnnals of Clinical Microbiology, 2013
In 1884 Robert Koch and Friedrich Loeffler published Koch’s Postulates defining our historical understanding of the relationship between an organism and infection: one organism: one disease. In the last decade with research on the microbial community living on and in humans, a new concept of microbial diseases has emerged; that is, alterations of the ...
Patrick R. Murray
openalex   +3 more sources

The Menopausal Transition: Is the Hair Follicle “Going through Menopause”?

open access: yesBiomedicines, 2023
This article explores the link between menopause and changes in the hair follicle (HF) lifecycle, focusing on hormonal and metabolic dynamics. During menopause, hormonal fluctuations and aging can impact the HF, leading to phenomena such as thinning ...
Fabio Rinaldi   +4 more
doaj   +1 more source

Clinical Translation of Microbiome Research in Alopecia Areata: A New Perspective?

open access: yesCosmetics, 2022
The continuous research advances in the microbiome field is changing clinicians’ points of view about the involvement of the microbiome in human health and disease, including autoimmune diseases such as alopecia areata (AA).
Fabio Rinaldi   +4 more
doaj   +1 more source

IMG/M-HMP: A Metagenome Comparative Analysis System for the Human Microbiome Project

open access: goldPLoS ONE, 2012
The Integrated Microbial Genomes and Metagenomes (IMG/M) resource is a data management system that supports the analysis of sequence data from microbial communities in the integrated context of all publicly available draft and complete genomes from the three domains of life as well as a large number of plasmids and viruses.
Victor Markowitz   +12 more
openalex   +6 more sources

Effect of commonly used cosmetic preservatives on skin resident microflora dynamics

open access: yesScientific Reports, 2021
Human skin is populated by various microorganisms, the so-called microbiota, such as bacteria, viruses, yeasts, fungi, and archaea. The skin microbiota is in constant contact with the surrounding environment which can alter its eubiotic state.
Daniela Pinto   +5 more
doaj   +1 more source

The Integrative Human Microbiome Project: Dynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease [PDF]

open access: hybridCell Host & Microbe, 2014
Much has been learned about the diversity and distribution of human-associated microbial communities, but we still know little about the biology of the microbiome, how it interacts with the host, and how the host responds to its resident microbiota.
Butte, Atul, NULL, NULL
  +6 more sources

Evaluation of 16S rDNA-based community profiling for human microbiome research. [PDF]

open access: yesPLoS ONE, 2012
The Human Microbiome Project will establish a reference data set for analysis of the microbiome of healthy adults by surveying multiple body sites from 300 people and generating data from over 12,000 samples.
Jumpstart Consortium Human Microbiome Project Data Generation Working Group
doaj   +1 more source

Evaluation of Tolerance and Trichological Efficacy of a Food Supplement in Men and Women with Telogen Effluvium-like Disorder

open access: yesCosmetics, 2022
Hair thinning is a very common problem in dermatology, affecting both men and women, and can strongly impact the quality of life of subjects. In this view, therapies that aim to reduce the appearance of thinning by delaying, arresting, or reversing the ...
Fabio Rinaldi   +2 more
doaj   +1 more source

The Human Microbiome Project strategy for comprehensive sampling of the human microbiome and why it matters

open access: greenThe FASEB Journal, 2012
The Human Microbiome Project used rigorous good clinical practice standards to complete comprehensive body site sampling in healthy 18- to 40-yr-old adults, creating an unparalleled reference set of microbiome specimens. To ensure that specimens represented minimally perturbed microbiomes, we first screened potential participants using exclusion ...
Kjersti M. Aagaard   +14 more
openalex   +6 more sources

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