Results 31 to 40 of about 564,378 (281)

The Human Microbiome Project: Getting to the Guts of the Matter in Cancer Epidemiology [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2008
With the completion of the Human Genome Project, we have a new array of tools to carry out genetic epidemiologic studies. Thanks to the Human Microbiome Project ([1][1]), launched recently by the NIH Roadmap for Medical Research, we will be in a position
Johanna W. Lampe
semanticscholar   +4 more sources

Human Papillomavirus Community in Healthy Persons, Defined by Metagenomics Analysis of Human Microbiome Project Shotgun Sequencing Data Sets

Journal of Virology, 2014
Human papillomavirus (HPV) causes a number of neoplastic diseases in humans. Here, we show a complex normal HPV community in a cohort of 103 healthy human subjects, by metagenomics analysis of the shotgun sequencing data generated from the NIH Human ...
Yingfei Ma, Ramana Madupu, Ulaş Karaöz, Carlos W. Nossa, Liying Yang, Shibu Yooseph, Patrick Yachimski, Eoin Brodie, William Nelson, Zhiheng Pei   +9 more
openalex   +2 more sources

Misclassification of a whole genome sequence reference defined by the Human Microbiome Project: a detrimental carryover effect to microbiome studies [PDF]

, 2019
Taxonomic classification is an essential step in the analysis of microbiome data that depends on a reference database of whole genome sequences. Taxonomic classifiers are built on established reference species, such as the Human Microbiome Project ...
DJ Darwin R. Bandoy, Bihua C. Huang, Bart C. Weimer   +2 more
openalex   +2 more sources

The Human Microbiome Project: An Opportunity to Engage Undergraduates in Research

Procedia Computer Science, 2012
AbstractThe Human Microbiome Project (HMP) aims to characterize the diversity of microbial species found at several different sites on the human body. The HMP has sequenced hundreds of microbial reference genomes from multiple body sites and provides a wealth of primary genomic sequence data for analysis.
Anne Rosenwald, Gaurav Arora, Ramana Madupu, Jennifer Roecklein‐Canfield, Janet Russell   +4 more
semanticscholar   +4 more sources

Structure, function and diversity of the healthy human microbiome

Nature, 2012
Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although diet, environment, host genetics and
C. Huttenhower, D. Gevers, R. Knight, Sahar Abubucker, J. Badger, A. Chinwalla, H. Creasy, A. Earl, Michael G. Fitzgerald, R. Fulton, M. Giglio, Kymberlie Hallsworth-Pepin, E. Lobos, R. Madupu, V. Magrini, John Martin, M. Mitreva, D. Muzny, E. Sodergren, J. Versalovic, A. Wollam, K. Worley, J. Wortman, Sarah K. Young, Qiandong Zeng, K. Aagaard, Olukemi O. Abolude, E. Allen-Vercoe, E. Alm, Lucia Alvarado, G. Andersen, S. Anderson, Elizabeth L. Appelbaum, H. Arachchi, G. Armitage, Cesar Arze, T. Ayvaz, Carl C. Baker, L. Begg, Tsegahiwot Belachew, Veena Bhonagiri, Monika Bihan, M. Blaser, Toby Bloom, Vivien R. Bonazzi, J. Brooks, G. Buck, C. Buhay, D. Busam, Joseph L. Campbell, S. Canon, B. Cantarel, P. Chain, I. Chen, Lei Chen, Shaila Chhibba, Ken Chu, Dawn M. Ciulla, J. Clemente, S. Clifton, S. Conlan, J. Crabtree, M. Cutting, Noam J. Davidovics, Catherine C. Davis, T. DeSantis, C. Deal, Kimberley D. Delehaunty, F. Dewhirst, E. Deych, Yan Ding, D. Dooling, Shannon P. Dugan, W. Dunne, A. S. Durkin, Robert C. Edgar, R. Erlich, Candace N. Farmer, R. Farrell, Karoline Faust, M. Feldgarden, Victor Felix, Sheila A Fisher, A. Fodor, L. Forney, Les Foster, V. D. Francesco, Jonathan Friedman, Dennis C. Friedrich, C. Fronick, L. Fulton, Hongyu Gao, Nathalia Garcia, G. Giannoukos, C. Giblin, Maria Y. Giovanni, J. Goldberg, Johannes Goll, Antonio Gonzalez, Allison D. Griggs, Sharvari Gujja, S. Haake, B. Haas, Holli A. Hamilton, Emily L. Harris, Theresa A. Hepburn, Brandi N. Herter, D. Hoffmann, M. Holder, Clinton Howarth, Katherine H. Huang, Susan M. Huse, J. Izard, J. Jansson, Huaiyang Jiang, Catherine Jordan, Vandita Joshi, J. Katancik, W. Keitel, S. Kelley, C. Kells, N. King, D. Knights, H. Kong, O. Koren, S. Koren, Karthik Kota, C. Kovar, N. Kyrpides, P. S. Rosa, Sandy Lee, K. P. Lemon, N. Lennon, Cecil M. Lewis, L. Lewis, R. Ley, Kelvin Li, K. Liolios, Bo Liu, Yue Liu, C. Lo, C. Lozupone, R. Lunsford, T. Madden, A. Mahurkar, P. Mannon, E. Mardis, V. Markowitz, K. Mavromatis, J. McCorrison, Daniel McDonald, J. Mcewen, A. McGuire, P. Mcinnes, Teena Mehta, K. Mihindukulasuriya, J. Miller, P. Minx, I. Newsham, C. Nusbaum, M. O'Laughlin, Joshua Orvis, I. Pagani, Krishna Palaniappan, Shital M. Patel, Matthew D. Pearson, Jane L. Peterson, M. Podar, C. Pohl, K. Pollard, Mihai Pop, M. Priest, L. Proctor, X. Qin, J. Raes, J. Ravel, J. Reid, Mina Rho, R. Rhodes, Kevin P. Riehle, M. Rivera, B. Rodriguez-Mueller, Y. Rogers, M. C. Ross, C. Russ, Ravi K. Sanka, P. Sankar, J. Sathirapongsasuti, J. Schloss, P. Schloss, T. Schmidt, M. Scholz, L. Schriml, Alyxandria M. Schubert, N. Segata, J. Segre, W. Shannon, R. Sharp, T. Sharpton, N. Shenoy, N. Sheth, Gina A. Simone, Indresh Singh, C. Smillie, J. Sobel, Daniel D. Sommer, P. Spicer, G. Sutton, S. Sykes, D. Tabbaa, M. Thiagarajan, Chad Tomlinson, M. Torralba, Todd J. Treangen, R. Truty, T. Vishnivetskaya, Jason R. Walker, Lu Wang, Zhengyuan O. Wang, D. Ward, W. Warren, M. Watson, Christopher Wellington, K. Wetterstrand, J. White, Katarzyna Wilczek-Boney, Yuanqing Wu, K. Wylie, T. Wylie, C. Yandava, Liang Ye, Yuzhen Ye, Shibu Yooseph, Bonnie P. Youmans, Lan Zhang, Yanjiao Zhou, Yiming Zhu, L. Zoloth, Jeremy D. Zucker, B. Birren, R. Gibbs, S. Highlander, B. Methé, K. Nelson, J. Petrosino, G. Weinstock, R. Wilson, O. White   +247 more
exaly   +2 more sources

Species-Level Analysis of DNA Sequence Data from the NIH Human Microbiome Project

PLoS ONE, 2012
Background Outbreaks of antibiotic-resistant bacterial infections emphasize the importance of surveillance of potentially pathogenic bacteria. Genomic sequencing of clinical microbiological specimens expands our capacity to study cultivable, fastidious ...
Sean Conlan, Heidi H. Kong, Julia A. Segre   +2 more
openalex   +3 more sources

HMP16SData: Efficient Access to the Human Microbiome Project Through Bioconductor. [PDF]

Am J Epidemiol, 2019
Schiffer L, Azhar R, Shepherd L, Ramos M, Geistlinger L, Huttenhower C, Dowd JB, Segata N, Waldron L.   +8 more
europepmc   +3 more sources

NIH Builds Substantial Human Microbiome Project [PDF]

Microbe Magazine, 2009
The human genome proved surprisingly skimpy, encoding somewhere in the range of a mere 20,000 proteins, on the same order as the fruit fly genome—a psychologically humbling number. However, humans provide a scaffold upon which microbes build elaborate ecosystems and, by young adulthood, each of us carries many more microbial genes than our own.
Marcia Stone
openalex   +3 more sources

Microbial community profiling for human microbiome projects: Tools, techniques, and challenges [PDF]

Genome Research, 2009
High-throughput sequencing studies and new software tools are revolutionizing microbial community analyses, yet the variety of experimental and computational methods can be daunting. In this review, we discuss some of the different approaches to community profiling, highlighting strengths and weaknesses of various experimental approaches, sequencing ...
Micah Hamady, Rob Knight
openalex   +5 more sources

Human oral microbiome characterization and its association with environmental microbiome revealed by the Earth Microbiome Project [PDF]

, 2019
AbstractThe oral cavity is an important window for the microbial communication between environment and the human body. The oral microbiome plays an important role in human health. Here, we analyzed 447 datasets from human oral samples published by the Earth Microbiome Project (EMP).
Jinlan Wang, Dandan Li, Jianing Wang, Zheng Zhang   +3 more
openalex   +3 more sources