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The Human Microbiome Project: Beginning and Future Status [PDF]
In 1884 Robert Koch and Friedrich Loeffler published Koch’s Postulates defining our historical understanding of the relationship between an organism and infection: one organism: one disease. In the last decade with research on the microbial community living on and in humans, a new concept of microbial diseases has emerged; that is, alterations of the ...
Patrick R. Murray
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The Menopausal Transition: Is the Hair Follicle “Going through Menopause”?
This article explores the link between menopause and changes in the hair follicle (HF) lifecycle, focusing on hormonal and metabolic dynamics. During menopause, hormonal fluctuations and aging can impact the HF, leading to phenomena such as thinning ...
Fabio Rinaldi+4 more
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Clinical Translation of Microbiome Research in Alopecia Areata: A New Perspective?
The continuous research advances in the microbiome field is changing clinicians’ points of view about the involvement of the microbiome in human health and disease, including autoimmune diseases such as alopecia areata (AA).
Fabio Rinaldi+4 more
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IMG/M-HMP: A Metagenome Comparative Analysis System for the Human Microbiome Project
The Integrated Microbial Genomes and Metagenomes (IMG/M) resource is a data management system that supports the analysis of sequence data from microbial communities in the integrated context of all publicly available draft and complete genomes from the three domains of life as well as a large number of plasmids and viruses.
Victor Markowitz+12 more
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Effect of commonly used cosmetic preservatives on skin resident microflora dynamics
Human skin is populated by various microorganisms, the so-called microbiota, such as bacteria, viruses, yeasts, fungi, and archaea. The skin microbiota is in constant contact with the surrounding environment which can alter its eubiotic state.
Daniela Pinto+5 more
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The Integrative Human Microbiome Project: Dynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease [PDF]
Much has been learned about the diversity and distribution of human-associated microbial communities, but we still know little about the biology of the microbiome, how it interacts with the host, and how the host responds to its resident microbiota.
Butte, Atul, NULL, NULL
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Evaluation of 16S rDNA-based community profiling for human microbiome research. [PDF]
The Human Microbiome Project will establish a reference data set for analysis of the microbiome of healthy adults by surveying multiple body sites from 300 people and generating data from over 12,000 samples.
Jumpstart Consortium Human Microbiome Project Data Generation Working Group
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After the Integrative Human Microbiome Project, what’s next for the microbiome community? [PDF]
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Hair thinning is a very common problem in dermatology, affecting both men and women, and can strongly impact the quality of life of subjects. In this view, therapies that aim to reduce the appearance of thinning by delaying, arresting, or reversing the ...
Fabio Rinaldi+2 more
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The Human Microbiome Project used rigorous good clinical practice standards to complete comprehensive body site sampling in healthy 18- to 40-yr-old adults, creating an unparalleled reference set of microbiome specimens. To ensure that specimens represented minimally perturbed microbiomes, we first screened potential participants using exclusion ...
Kjersti M. Aagaard+14 more
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