Why the Human Microbiome Project Should Motivate Epidemiologists to Learn Ecology [PDF]
If you are not an astronomer (amateur or otherwise), looking at the stars can be an exercise in frustration. Where are the constellations? The planets? A telescope doesn’t necessarily help: you can see things more clearly, but without knowing where to look and what to look for, you can’t tell what you are seeing.
Betsy Foxman, Deborah E. Goldberg
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Towards large-cohort comparative studies to define the factors influencing the gut microbial community structure of ASD patients. [PDF]
Differences in the gut microbiota have been reported between individuals with autism spectrum disorders (ASD) and neurotypical controls, although direct evidence that changes in the microbiome contribute to causing ASD has been scarce to date.
Debelius, Justine+5 more
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Human oral microbiome characterization and its association with environmental microbiome revealed by the Earth Microbiome Project [PDF]
AbstractThe oral cavity is an important window for the microbial communication between environment and the human body. The oral microbiome plays an important role in human health. Here, we analyzed 447 datasets from human oral samples published by the Earth Microbiome Project (EMP).
Wang, Jinlan+3 more
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Preservation Methods Differ in Fecal Microbiome Stability, Affecting Suitability for Field Studies. [PDF]
Immediate freezing at -20°C or below has been considered the gold standard for microbiome preservation, yet this approach is not feasible for many field studies, ranging from anthropology to wildlife conservation.
Amnon Amir+7 more
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Foregut microbiome in development of esophageal adenocarcinoma [PDF]
Esophageal adenocarcinoma (EA), the type of cancer linked to heartburn due to gastroesophageal reflux diseases (GERD), has increased six fold in the past 30 years. This cannot currently be explained by the usual environmental or by host genetic factors.
Aaron Tenney+27 more
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The Vaginal Microbiome: Disease, Genetics and the Environment [PDF]
The vagina is an interactive interface between the host and the environment. Its surface is covered by a protective epithelium colonized by bacteria and other microorganisms.
Bin Xie+28 more
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Steps in Metagenomics: Let’s Avoid Garbage in and Garbage Out [PDF]
Is metagenomics a revolution or a new fad? Metagenomics is tightly associated with the availability of next-generation sequencing in all its implementations.
Izard, Jacques
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Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stage [PDF]
Dental calculus, calcified oral plaque biofilm, contains microbial and host biomolecules that can be used to study historic microbiome communities and host responses.
CJ Adler+69 more
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Individual and collective identification in contemporary forensics [PDF]
It has long been understood that individual and collective identification are inexorably intertwined. This convergence is not limited to genetics. This paper discusses the convergence of individual and collective identification in a comparative analysis ...
Cole, SA
core
Species-level functional profiling of metagenomes and metatranscriptomes. [PDF]
Functional profiles of microbial communities are typically generated using comprehensive metagenomic or metatranscriptomic sequence read searches, which are time-consuming, prone to spurious mapping, and often limited to community-level quantification ...
A Sczyrba+58 more
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