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Computational Modeling of the Human Microbiome
Microorganisms, 2020 The impact of microorganisms on human health has long been acknowledged and studied, but recent advances in research methodologies have enabled a new systems-level perspective on the collections of microorganisms associated with humans, the human ...
Shomeek Chowdhury, Stephen S. Fong
doaj +1 more source
Regulatory effect of gut microbes on blood pressure
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 513-531, December 2022., 2022 The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan +6 more
wiley +1 more source
Gut Microbiota: A Future Clinical Magic Bullet to Manifest Pathogenic Disease in the Current Future
Journal of Pure and Applied Microbiology, 2023 Microbes proved to be the significant biotic factors that influence the health of humans. Gut microbiota remains an emerging field for understanding different aspects of microbiology, immunology, computational biology and food and nutrient ...
Pooja Rani Mina
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HT-MMIOW: A Hypothesis Test approach for Microbiome Mediation using Inverse Odds Weighting [PDF]
arXiv, 2023 The human microbiome has an important role in determining health. Mediation analyses quantify the contribution of the microbiome in the causal path between exposure and disease; however, current mediation models cannot fully capture the high dimensional, correlated, and compositional nature of microbiome data and do not typically accommodate ...
arxiv
Variable selection for sparse Dirichlet-multinomial regression with an application to microbiome data analysis [PDF]
Annals of Applied Statistics 2013, Vol. 7, No. 1, 418-442, 2013 With the development of next generation sequencing technology, researchers have now been able to study the microbiome composition using direct sequencing, whose output are bacterial taxa counts for each microbiome sample. One goal of microbiome study is to associate the microbiome composition with environmental covariates.
arxiv +1 more source
A hundred-year-old insight into the gut microbiome!
Gut Pathogens, 2009 As the National Institutes of Health-funded Human Microbiome Project enters its second phase, and as a major part of this project focuses on the human gut microbiome and its effects on human health, it might help us to travel a century back in time and ...
Aziz Ramy
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Gut microbiota: the next-gen frontier in preventive and therapeutic medicine?
Frontiers in Medicine, 2014 Our gut harbors an extremely diverse collection of trillions of microbes that, besides degrading the complex dietary constituents, execute numerous activities vital for our metabolism and immune health.
Ravinder eNagpal +2 more
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Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics
Frontiers in Pharmacology, 2020 The harmful impact of xenobiotics on the environment and human health is being more widely recognized; yet, inter- and intraindividual genetic variations among humans modulate the extent of harm, mostly through modulating the outcome of xenobiotic ...
Nehal Adel Abdelsalam +5 more
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Dependence Structure Analysis and Its Application in Human Microbiome
Mathematics, 2022 The human microbiome has been recently shown to be associated with disease risks and has important implications in risk stratification and precision medicine. Due to abundant taxa in the human body, microbiome data are high-dimensional and compositional.
Shilan Li +3 more
doaj +1 more source
DCMD: Distance-based Classification Using Mixture Distributions on Microbiome Data [PDF]
, 2020 Current advances in next generation sequencing techniques have allowed researchers to conduct comprehensive research on microbiome and human diseases, with recent studies identifying associations between human microbiome and health outcomes for a number of chronic conditions.
arxiv +1 more source