Results 141 to 150 of about 873,793 (309)

Anticipating sea-level rise and human migration: A review of empirical evidence and avenues for future research. [PDF]

Wiley Interdiscip Rev Clim Change, 2022
Duijndam SJ, Botzen WJW, Hagedoorn LC, Aerts JCJH.   +3 more
europepmc   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Climatic windows for human migration out of Africa in the past 300,000 years. [PDF]

Nat Commun, 2021
Beyer RM, Krapp M, Eriksson A, Manica A.
europepmc   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Human antigen R affects the migration and invasion of human lung cancer A549 cells and regulates E-cadherin suppressor Snail

, 2022
Shufang Shan, Qixue Bao, Guochen Ma, Yuqin Yao, Jingyuan Xiong, Jia You   +5 more
openalex   +2 more sources

Global genomic analyses of wheat powdery mildew reveal association of pathogen spread with historical human migration and trade. [PDF]

Nat Commun, 2022
Sotiropoulos AG, Arango-Isaza E, Ban T, Barbieri C, Bourras S, Cowger C, Czembor PC, Ben-David R, Dinoor A, Ellwood SR, Graf J, Hatta K, Helguera M, Sánchez-Martín J, McDonald BA, Morgounov AI, Müller MC, Shamanin V, Shimizu KK, Yoshihira T, Zbinden H, Keller B, Wicker T.   +22 more
europepmc   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

SIPA1 promotes invasion and migration in human oral squamous cell carcinoma by ITGB1 and MMP7

, 2017
Toshikazu Takahara, Atsushi Kasamatsu, Masanobu Yamatoji, Manabu Iyoda, Hiroki Kasama, Tomoaki Saito, Shin Takeuchi, Yosuke Endo‐Sakamoto, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa   +10 more
openalex   +1 more source

Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes. [PDF]

Nat Commun, 2021
Razali RM, Rodriguez-Flores J, Ghorbani M, Naeem H, Aamer W, Aliyev E, Jubran A, Qatar Genome Program Research Consortium, Clark AG, Fakhro KA, Mokrab Y.   +10 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source