Results 121 to 130 of about 301,836 (334)

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

The global status of human milk banking

Maternal and Child Nutrition
Human milk provides essential nutrition for infants and holds many health benefits for infants and mothers. When a mother's own milk is not available for her infant, the World Health Organization recommends feeding donor human milk (DHM) from a human ...
Kiersten Israel‐Ballard, Emily LaRose, Kimberly Mansen   +2 more
doaj   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Donation barriers, enablers, patterns and predictors of milk bank donors in the United States and United Kingdom

Maternal and Child Nutrition
Pasteurised donor human milk is recommended for very low birthweight infants who do not have access to their mother's milk. Although the use of donor milk continues to increase, little is known about the donation experiences of milk bank donors. We aimed
Bruna Gutierrez dosSantos, Natalie Shenker, Gillian Weaver, Maryanne T. Perrin   +3 more
doaj   +1 more source

Setting up the first human milk bank in Uganda: a success story from Nsambya hospital

Frontiers in Nutrition
BackgroundThe World Health Organization (WHO) strongly recommends the use of donor human milk (DHM) for low birth weight infants when mother’s own milk is unavailable or insufficient. However, the use of DHM requires the availability of human milk banks (
Victoria Nakibuuka, Janat Kainza, Ritah Nasiima, Sanyu Nalunga, Ritah Nazziwa, Hamim Mponye, Christinah Nuwahereza, Ronald Kyambadde, Racheal Nantenza, Caroline Nassonko, Barbara Nalubwama, Immaculate Nabwami, Madrine Nabaliira, Cleophas Kabategweta, Olivia Nalule, Joannita Nampijja, Barbara Namugga, Peter Kirabira, Gillian Weaver   +18 more
doaj   +1 more source

THE IMPACT OF GLOBALIZATION ON INVESTMENT AND AGRICULTURAL RESTRUCTURING: EVIDENCE FROM POLISH AGRICULTURE [PDF]

We analyze the impact of assistance programs offered by food processors to supplying farms based on an original survey of dairy farms and companies in Poland.
Dries, Liesbeth, Swinnen, Johan F.M.
core   +1 more source

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation

Advanced Science, EarlyView.
A hyaluronic acid methacrylate (HAMA) hydrogel incorporating DNA tetrahedrons loaded with Asiatic acid (TDN@AA) was developed. HM‐TDN@AA promotes angiogenesis of endothelial cells (ECs), inhibits osteoclastogenesis from bone marrow–derived macrophages (BMDMs), and enhances osteogenesis of mesenchymal stem cells (MSCs) via STAT3‐mediated mitochondrial ...
Yiwen Huang, Yiming Zhang, Yisheng Feng, Qixiang Yang, Beiyuan Gao, Haiyang Xu, Cheng Huang, Kaili Lin, Yuanzhi Xu, Peiqi Zhu   +9 more
wiley   +1 more source

The inter-linkages between rapid growth in livestock production, climate change, and the impacts on water resources, land use, and deforestation [PDF]

Livestock systems globally are changing rapidly in response to human population growth, urbanization, and growing incomes. This paper discusses the linkages between burgeoning demand for livestock products, growth in livestock production, and the impacts
Herrero, Mario, Thornton, Philip K.
core  

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source

Sequential Changes in the Antimicrobial Protein Concentrations in Human Milk during Lactation and Its Relevance to Banked Human Milk [PDF]

, 1985
D. I. Lewis‐Jones, M.S. Lewis‐Jones, R. C. Connolly, D. C. Lloyd, C West   +4 more
openalex   +1 more source