Results 41 to 50 of about 154,657 (284)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Regulation of Donor Human Milk at European level: a new bridge for successful breastfeeding of sick preterm infants

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2021
At present, in the EU, there is a specific Legislation on Blood, Tissue and Cells (BTC), but there is a lack of regulation on Donor Human Milk and Human Milk Banks.
Enrico Bertino
doaj   +1 more source

Temporal and spatial differences in microbial composition during the manufacture of a Continental-type cheese [PDF]

open access: yes, 2015
peer-reviewedWe sought to determine if the time, within a production day, that a cheese is manufactured has an influence on the microbial community present within that cheese.
Cotter, Paul D.   +5 more
core   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Nutritional adequacy of a novel human milk fortifier from donkey milk in feeding preterm infants: study protocol of a randomized controlled clinical trial

open access: yesNutrition Journal, 2018
Background Fortification of human milk is a standard practice for feeding very low birth weight infants. However, preterm infants often still experience suboptimal growth and feeding intolerance.
Alessandra Coscia   +12 more
doaj   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Milk Kinship and Implications for Human Milk Banking: A Review [PDF]

open access: yesWomen’s Health Bulletin, 2016
Context: Articles discussing human milk banking and the sharing of milk among women have increasingly been appearing in the medical and nursing literature in the early-21st century.
Virginia Thorley
doaj   +1 more source

Growth of Very Preterm Infants in a Low-Resourced Rural Setting after Affiliation with a Human Milk Bank

open access: yesChildren, 2022
The extrauterine growth restriction (EUGR) of very preterm infants has been associated with long-term complications and neurodevelopmental problems. EUGR has been reported at higher rates in low resource settings.
Chia-Huei Chen   +8 more
doaj   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

open access: yesAdvanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang   +15 more
wiley   +1 more source

Human milk banks: lights and shadows

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2014
Breastfeeding is the most appropriate source of nutrition also for preterm infants. When mother’s own milk is not available, donor human milk (DHM), provided from a human milk bank (HMB), or formula can be used. Infants fed DHM grow at a slower rate than
Arianna Aceti   +2 more
doaj   +1 more source

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