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Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth

open access: yes
Chapman JA   +20 more
europepmc   +1 more source

Challenges and Pitfalls in Human Milk Oligosaccharide Analysis [PDF]

open access: yesNutrients, 2019
Human milk oligosaccharides have been recognized as an important, functional biomolecule in mothers' milk. Moreover, these oligosaccharides have been recognized as the third most abundant component of human milk, ranging from 10-15 g/L in mature milk and
Sander S van Leeuwen
exaly   +2 more sources
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Oligosaccharides of Human Milk

Nature, 1957
THE presence of fucose as a constituent sugar in oligosaccharides obtained from human milk was reported by Kuhn1 in 1952. Since that time Kuhn and his associates have characterized four oligosaccharides from this source, in all of which fucose is found: a trisaccharide, fucosido-lactose; two pentasaccharides referred to as lacto-N-fucopentaoses I and ...
F H, MALPRESS, F E, HYTTEN
openaire   +2 more sources

Human milk oligosaccharides

Journal of Pediatric Gastroenterology and Nutrition, 2016
Human milk oligosaccharides are very complex molecules and hence are difficult to synthesize. These specialty carbohydrates are consequently very expensive and not available in sufficient quantities. Enzymatic synthesis is efficient for relatively simple carbohydrates but cannot be used for more complex carbohydrates.
openaire   +2 more sources

Biotechnological Production of Human Milk Oligosaccharides

Biotechnology Advances, 2012
Human milk contains a large variety of oligosaccharides (HMOs) that have the potential to modulate the gut flora, affect different gastrointestinal functions, and influence inflammatory processes. This review introduces the recent advances in the microbial and coupled enzymatic methods to produce HMOs with grouping them into trisaccharides ...
Jaehan Kim, Jin-Ho Seo, Nam Soo Han
exaly   +3 more sources

Human Milk Oligosaccharides

2001
Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
R. Erney   +4 more
openaire   +1 more source

Human milk and related oligosaccharides as prebiotics

Current Opinion in Biotechnology, 2013
Human milk oligosaccharides (HMO) are believed to have a range of biological activities beyond providing nutrition to the infant. Principal among these is that they may act as prebiotics. Prebiotics are dietary ingredients, usually oligosaccharides that provide a health benefit to the host mediated by the modulation of the human gut microbiota.
Daniela, Barile, Robert A, Rastall
openaire   +2 more sources

Bifidobacterial utilization of human milk oligosaccharides

International Journal of Food Microbiology, 2011
A promising strategy to improve health is the rational manipulation of one's beneficial microbiota via dietary interventions. This is observed in nature where specific bifidobacteria utilize human milk oligosaccharides (HMOs) that are encountered within the breast-fed infant colon. Bifidobacterium longum subsp.
openaire   +2 more sources

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