Results 121 to 130 of about 8,048,182 (359)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Hobbesian Conception of Human Nature: Moral Implications for Nigeria Society [PDF]

open access: yes, 2019
This work is on Hobbesian Conception of Human Nature: Moral Implications for Nigeria Society. It will be absurd indeed to discuss about Ethics and Society without talking about the concept of human nature.
Big-Alabo, Sotonye
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Can we get human nature right? [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Berent I.
europepmc   +1 more source

Moral Teachings in the Holy Books, the Bible and the Quran, About the Relationship of the Human to Nature: A Macedonian Research Project

open access: yes, 2019
The subject matter of this manuscript is the separation and actualization of the thematic areas of the holy books, the Bible and the Quran, in which the human-nature relationship is elaborated, indicated or specified.
Cacanoska, Ruzhica   +6 more
core  

Tocqueville, Pascal, and the Transcendent Horizon [PDF]

open access: yes, 2007
Most students of Tocqueville know of his remark, “There are three men with whom I live a little every day; they are Pascal, Montesquieu, and Rousseau.” In this paper I trace out the contours of Pascal’s influence upon Tocqueville’s understanding of the ...
Jech, Alexander
core  

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