Results 121 to 130 of about 14,023,849 (296)

Does socioeconomic position and gender affect human-nature interactions? [PDF]

J Public Health (Berl), 2022
Tiscareno-Osorno X, Hossaini J, Chabursky S, Sayed N, Temizarabaci I, Hähl W, Beckmann J.   +6 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

A network perspective of human-nature interactions in dynamic and fast-changing landscapes. [PDF]

Natl Sci Rev, 2023
Bodin Ö, Chen H.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Covid-related surge in global wild bird feeding: Implications for biodiversity and human-nature interaction. [PDF]

PLoS One, 2023
Doremus J, Li L, Jones D.
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Can we get human nature right? [PDF]

Proc Natl Acad Sci U S A, 2021
Berent I.
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Pandemics, conservation, and human-nature relations. [PDF]

Clim Chang Ecol, 2021
Gebara MF, May PH, Platais G.
europepmc   +1 more source

Current and future impacts on the marine environment : the challenges to achieve good environmental status : Malta report [PDF]

, 2015
The Mediterranean Sea is increasingly exploited by a range of maritime activities, all of which are predicted to expand substantially over the next 20 years: wind farms, oil extraction, cables, shipping routes, fisheries and other human activities ...
Galdies, Charles, Refalo, Marvic, Nature Trust (Malta)   +2 more
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